AD criteria, according to Hanifin and Rajka [27]
| Major criteria | Minor criteria |
|---|---|
| - pruritus | - dryness of the skin |
| - chronic, recurrent dermatitis | - fish-scale skin |
| - typical morphology and localization of the lesions | - immediate skin reactivity |
| - personal or family history of atopy | - elevated IgE levels |
| - early age of onset | |
| - susceptibility to recurrent | |
| skin infections | |
| - nonspecific hand/foot dermatitis | |
| - nipple eczema | |
| - cheilitis | |
| - recurrent conjunctivitis | |
| - Dennie-Morgan infraorbital fold | |
| - keratoconus | |
| - cataracts | |
| - darkening around the eyes | |
| - pityriasis alba | |
| - anterior neck folds | |
| - itch when sweating | |
| - food intolerance | |
| - intolerance to wool | |
| - exacerbations after stress | |
| - white dermographism | |
| - facial erythema | |
| - perifollicular accentuation | |