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Spheroids as 3D Cell Models for Testing of Drugs Cover

Spheroids as 3D Cell Models for Testing of Drugs

Open Access
|Aug 2023

References

  1. AGGARWAL BB, DANDA D, GUPTA S, GEHLOT P. Models for prevention and treatment of cancer: Problems vs promises. Biochemical Pharmacology, 2009;78(9):1083–1094.
  2. AMELIAN A, WASILEWSKA K, MEGIAS D, WINNICKA K. Application of standard cell cultures and 3D in vitro tissue models as an effective tool in drug design and development. Pharmacological Reports, 2017; 69(5):861–870.
  3. BAKER BM, CHEN CS. Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues. Journal of Cell Science, 2012;125(13):3015–3024.
  4. BRESLIN S, O’DRISCOLL L. Three-dimensional cell culture: the missing link in drug discovery. Drug Discovery Today, 2013;18(5–6):240–249.
  5. COSTA EC, DE MELO-DIOGO D, MOREIRA AF, CARVALHO MP, CORREIA IJ. Spheroids Formation on Non-Adhesive Surfaces by Liquid Overlay Technique: Considerations and Practical Approaches. Biotechnology Journal, 2017;13(1).
  6. COSTA EC, GASPAR VM, COUTINHO P, CORREIA IJ. Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models. Biotechnology and Bioengineering, 2014;111(8):1672–1685.
  7. COSTA EC, MOREIRA AF, DE MELO-DIOGO D, GASPAR VM, CARVALH MP, CORREIA IJ. 3D tumor spheroids: an overview on the tools and techniques used for their analysis. Biotechnology Advances. 2016;1427–1441.
  8. DUVAL K, GROVER H, HAN LH, MOU Y, PEGORARO AF, FREDBERG J, CHEN Z. Modeling Physiological Events in 2D vs. 3D Cell Culture. Physiology, 2017;32(4):266–277.
  9. EDMONDSON R, BROGLIE JJ, ADCOCK AF, YANG L. Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors. Assay Drug Dev Technol. 2014;12(4):207–218.
  10. HARRISON RH, GREENMAN MJ, FRANKLIN PM, JACKSON JM. Observations of the living developing nerve fibes. The Anatomical Record. 1907; 1 (5):116–128.
  11. HOARAU-VÉCHOT J, RAFII A, TOUBOUL C, PASQUIER J. Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions? International Journal of Molecular Sciences. 2018;(1):181.
  12. JENSEN C, TENG Y. Isittime to start transitioning from 2D to 3D cell culture? Frontiers in Molecular Biosciences. 2020;7:33.
  13. JOSEPH JS, MALINDISA ST, NTWASA M. Two-Dimensional (2D) and Three-Dimensional (3D) Cell Culturing in Drug Discovery. Intechopen. 2018.
  14. KAPAŁCZYŃSKA M, KOLENDA T, PRZYBYŁA W, et al. 2D and 3D cell cultures – a comparison of different types of cancer cell cultures. Archives of Medical Science. 2018;14(4):910–919.
  15. KHAITAN D, CHANDNA S, ARYA M, DWARAKANATH B. Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy. J Transl Med. 2006;4:12.
  16. LANDECKER, H. Culturing Life: How Cells Became Technologies. Harvard University Press. 2010. ISBN 9780-6740-3990-2.
  17. LANDRY J, BERNIER D, OUELLET C, GOYETTE R, MARCEAU N. Spheroidal Aggregate Culture of Rat Liver Cells: Histotypic Reorganization, Biomatrix Deposition, and Maintenance of Functional Activities. J Cell Bio. 1985;101(3):914–23.
  18. LAZZARI G, COUVVREUR P, MURA S. Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines. Polymer Chemistry. 2017;8:4947–4969.
  19. LEE J, CUDDIHY MJ, KOTOV NA. Three-dimensional cell culture matrices: state of the art. Tissue Eng part B Rev. 2008;14 (1): 61–86.
  20. LI H, FAN X, HOUGHTON JM. Tumor microenvironment: The role of the tumor stroma in cancer. Journal of Cellular Biochemistry. 2007;805–815.
  21. MEHTA G, HSIAO AY, INGRAM M, LUKER GD, TAKAYAMA S. Opportunities and Challenges for use of Tumor Spheroids as Models to Test Drug Delivery and Efficacy. J Control Release. 2012;164(2):192–204.
  22. PAMPALONI F, REYNAUD EG, STELZER EH. K. The third dimension bridges the gap between cell culture and live tissue. Nature Reviews Molecular Cell Biology, 2007;8(10):839–845.
  23. WANG L, GUO H, LIN C, YANG L, WANG X. Enrichment and characterization of cancer stem-like cells from a cervical cancer cell line. Molecular Medicine Reports. 2014;7:2117–2123.
Language: English
Page range: 37 - 43
Submitted on: Jun 22, 2023
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Accepted on: Jun 23, 2023
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Published on: Aug 24, 2023
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Related subjects:

© 2023 E. Nováková, V. Mikušová, M. Šupolíková, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.