Have a personal or library account? Click to login
Microemulsions as the Potential Delivery System for Nimodipine Cover

Microemulsions as the Potential Delivery System for Nimodipine

European Pharmaceutical Journal
Volume 70 (2023): Issue s1 (December 2023)
By: M. Čuchorová,  M. Špaglová and  M. Papadakos  
Open Access
|Aug 2023

Figures & Tables

Figure 1.

The released amount of NIM from microemulsions and microemulsion gel systems compared to a water solution of NIM.
The released amount of NIM from microemulsions and microemulsion gel systems compared to a water solution of NIM.

Physicochemical properties of microemulsions_

PropertiesME1ME2
Particle size (nm) ± SD42.47 ± 11.2561.4 ± 6.043
Viscosity (mPa s) ± SD33.036 ± 0.06131.281 ± 0.686
Transmittance ± SD99.009 ± 0.43497.882 ± 0.168
pH ± SD5.08 ± 0.105.21 ± 0.10
Conductivity (µs cm−1) ± SD33.9 ± 0.140.6 ± 0.1
Solubility of NIM (µg mL−1) ± SD73.65 ± 12.03247.55 ± 26.31

Drug release from microemulsion gel systems and their viscosity_

SampleViscositya (mPa s)The cumulative amount of NIM after 6 h (µg cm−2) ± SDb
ME1 XG gel145.10556.20 ± 0.630
ME1 HEC gel835.332483.83 ± 0.795
ME2 XG gel184.301511.40 ± 0.436
ME2 HEC gel194.603226.28 ± 0.486
DOI: https://doi.org/10.2478/afpuc-2023-0004 | Journal eISSN: 2453-6725
Journal RSS Feed
Language: English
Page range: 34 - 36
Submitted on: Jun 20, 2023
|
Accepted on: Jun 22, 2023
|
Published on: Aug 24, 2023
Published by: Comenius University in Bratislava, Faculty of Pharmacy
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
microemulsion,
nimodipine,
hydroxyethyl cellulose,
xanthan gum
Related subjects:
Pharmacy,
Pharmacy, other

© 2023 M. Čuchorová, M. Špaglová, M. Papadakos, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Previous articleVolume 70 (2023): Issue s1 (December 2023)Next article