Figure 1

Figure 2

Figure 3

Figure 4

Results of quantitative determination of parthenolide in batches of feverfew herb_
| Batch No. | The region of collection of raw materials | Requirements, % | Xavr±ΔX, % | Criterion satisfaction |
|---|---|---|---|---|
| Rs 864 | Zhytomyr region | ≥ 0.2 | 0.22 ± 0.01 | Satisfied |
| Rs 865 | Cherkasy region | 0.16 ± 0.06 | No satisfied | |
| Rs 866 | Sumy region | 0.27 ± 0.11 | Satisfied | |
| Rs 867 | Dnipropetrovsk region | 0.26 ± 0.09 | Satisfied | |
| Rs 868 | Kharkiv region | 0.22 ± 0.02 | Satisfied | |
| Rs 869 | Poltava region | 0.24 ± 0.04 | Satisfied | |
| Rs 870 | Kyiv region | 0.39 ± 0.10 | Satisfied |
The linearity parameters of the quantitative determination method_
| Parameter | Requirements | Received value | Criterion satisfaction |
|---|---|---|---|
| |a| | ≤ 4.096 | 0.32 | Satisfied |
| S0 | ≤ 2.72 | 2.57 | Satisfied |
| r | > 0.9821 | 0.9998 | Satisfied |
Climatic and edaphic conditions of the regions during the growing season of feverfew herb
| The region of collection of raw materials | Soil | Solar insolation, kWh/m2/day | Air temperature, °C | Precipitation, mm |
|---|---|---|---|---|
| Zhytomyr region | black | 3.10–5.21 | +21–+26 | 55–85 |
| Cherkasy region | sod-gley / sod-podzolic | 3.99–5.54 | +20–+25 | 52–73 |
| Sumy region | black | 3.12–5.24 | +22–+33 | 50–75 |
| Dnipropetrovsk region | black | 3.11–5.22 | +22–+30 | 51–74 |
| Kharkiv region | black | 3.12–5.25 | +19–+24 | 55–85 |
| Poltava region | black | 3.13–5.23 | +21–+26 | 50–69 |
| Kyiv region | black | 3.12–5.25 | +20–+25 | 50–70 |
The results of the evaluation of the accuracy and precision of the HPLC method_
| Parameter | Index | Criterion | Criterion satisfaction | |
|---|---|---|---|---|
| Requirements for statistical insignificance | Requirements for practical insignificance | |||
| 0.79 | ≤ 1.26% | ≤ 2.048% | Satisfied | |
| ΔZ | 2.83 | ≤ 6.4% | Satisfied | |