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Study of the Qualitative Composition and Quantitative Content of Parthenolide in the Feverfew (Tanacetum Parthenium) Herb Cultivated in Ukraine Cover

Study of the Qualitative Composition and Quantitative Content of Parthenolide in the Feverfew (Tanacetum Parthenium) Herb Cultivated in Ukraine

Open Access
|Jan 2021

Figures & Tables

Figure 1

TLC of feverfew herb batches and parthenolide reference sample (RS).
TLC of feverfew herb batches and parthenolide reference sample (RS).

Figure 2

Chromatogram of parthenolide reference solution.
Chromatogram of parthenolide reference solution.

Figure 3

Chromatogram of the test solution.
Chromatogram of the test solution.

Figure 4

Graph of linear dependence Yi = b * Xi + a for parthenolide reference solution.
Graph of linear dependence Yi = b * Xi + a for parthenolide reference solution.

Results of quantitative determination of parthenolide in batches of feverfew herb_

Batch No.The region of collection of raw materialsRequirements, %Xavr±ΔX, %Criterion satisfaction
Rs 864Zhytomyr region≥ 0.20.22 ± 0.01Satisfied
Rs 865Cherkasy region0.16 ± 0.06No satisfied
Rs 866Sumy region0.27 ± 0.11Satisfied
Rs 867Dnipropetrovsk region0.26 ± 0.09Satisfied
Rs 868Kharkiv region0.22 ± 0.02Satisfied
Rs 869Poltava region0.24 ± 0.04Satisfied
Rs 870Kyiv region0.39 ± 0.10Satisfied

The linearity parameters of the quantitative determination method_

ParameterRequirementsReceived valueCriterion satisfaction

|a|≤ 4.0960.32Satisfied
S0≤ 2.722.57Satisfied
r> 0.98210.9998Satisfied

Climatic and edaphic conditions of the regions during the growing season of feverfew herb

The region of collection of raw materialsSoilSolar insolation, kWh/m2/dayAir temperature, °CPrecipitation, mm
Zhytomyr regionblack3.10–5.21+21–+2655–85
Cherkasy regionsod-gley / sod-podzolic3.99–5.54+20–+2552–73
Sumy regionblack3.12–5.24+22–+3350–75
Dnipropetrovsk regionblack3.11–5.22+22–+3051–74
Kharkiv regionblack3.12–5.25+19–+2455–85
Poltava regionblack3.13–5.23+21–+2650–69
Kyiv regionblack3.12–5.25+20–+2550–70

The results of the evaluation of the accuracy and precision of the HPLC method_

ParameterIndexCriterionCriterion satisfaction
Requirements for statistical insignificanceRequirements for practical insignificance
0.79≤ 1.26%≤ 2.048%Satisfied
ΔZ2.83≤ 6.4%Satisfied
Language: English
Page range: 27 - 33
Submitted on: Sep 2, 2020
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Accepted on: Jan 18, 2021
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Published on: Jan 29, 2021
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Related subjects:

© 2021 K. R. Hordiei, T. N. Gontova, S. N. Gubar, M. S. Yaremenko, E. E. Kotova, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.