Neutrons in studies of phospholipid bilayers
and bilayer–drug interaction. II. Small-angle scattering

M. Belička; F. Devínsky; P. Balgavý

doi:10.2478/afpuc-2014-0011

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Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. II. Small-angle scattering

European Pharmaceutical Journal

Volume 61 (2014): Issue 2 (December 2014)

By: M. Belička, F. Devínsky and P. Balgavý

Open Access

|Dec 2014

Abstract

In this paper, we demonstrate several possibilities of using neutron scattering in pharmaceutical research based on examples of scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties of bilayers.

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Articles in this issue

DOI: https://doi.org/10.2478/afpuc-2014-0011 | Journal eISSN: 2453-6725

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Language: English

Page range: 12 - 20

Published on: Dec 30, 2014

Published by: Comenius University in Bratislava, Faculty of Pharmacy

In partnership with: Paradigm Publishing Services

Publication frequency: 2 issues per year

Keywords:

neutron scattering,

phospholipid liposomes,

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© 2014 M. Belička, F. Devínsky, P. Balgavý, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 61 (2014): Issue 2 (December 2014)