Neutrons in studies of phospholipid bilayers
and bilayer–drug interaction. II. Small-angle scattering

Belička, M.; Devínsky, F.; Balgavý, P.

doi:10.2478/afpuc-2014-0011

Abstract

In this paper, we demonstrate several possibilities of using neutron scattering in pharmaceutical research based on examples of scientific results achieved at our University. In this second part, elementary principles of small-angle neutron scattering and simple methods of scattering data evaluation are described. Results of scattering on bilayers in unilamellar liposomes with intercalated general anaesthetics, antimicrobials or cholesterol demonstrate the potential of this method at determination of structural properties of bilayers.

References

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Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. II. Small-angle scattering

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