Have a personal or library account? Click to login
Synthesis of new compounds of the aryloxyaminopropanol type and their HPLC enantioseparation Cover

Synthesis of new compounds of the aryloxyaminopropanol type and their HPLC enantioseparation

European Pharmaceutical Journal
Volume 60 (2013): Issue 2 (December 2013)
By: Čižmáriková R.,  Némethy A.,  Valentová J.,  Hroboňová K. and  Adamcová K.  
Open Access
|Dec 2013

References

  1. [1] Aboul-Enein HY, Ali I. HPLC enantiomeric resolution of nebivolol on normal and reversed amylose based chiral phases. Pharmazie. 2001;56:214-216.
    Search in Google Scholar
  2. [2] Agrawal YK, Patel RN. Chiral chromatographic separation of β-blockers. J Chromatogr B. 2005;820:23-31.10.1016/j.jchromb.2005.03.003
    Search in Google Scholar
  3. [3] Bojarsky J. Stereoselective chromatography of cardiovascular drugs: an update. J Biochem Biophys Methods. 2002;54:197-220.10.1016/S0165-022X(02)00143-4
    Search in Google Scholar
  4. [4] Bojarsky J, Aboul - Enein YH, Ghanem A. What/s new in chromatographic enantioseparations. Curr Anal Chem. 2005;1:59-77.10.2174/1573411052948433
    Search in Google Scholar
  5. [5] Bruchata K, Čižmarikova R. New derivatives of aryloxyaminopropanol- structure biological activity relationship. (Review in Slovak). Farm Obzor. 2010;79:287-293.
    Search in Google Scholar
  6. [6] Čižmarikova R, Dingova A, Kozlovsky J, Greksakova O.Derivatives of para-hydroxyacetophenones and parahydroxypropiophenones as novel potential beta-adrenolytic agent (in Slovak). Čes Slov Farm. 1990a;39:403-408.
    Search in Google Scholar
  7. [7] Čižmarikova R, Mlynarčik D, Greksakova O, Račanska E: Unspezifische Wirkungen der Derivate des p-Hydroxypropiophenones - potentielle Beta-Adrenolytika.Pharmazie. 1990b;45:142-143.
    Search in Google Scholar
  8. [8] Čižmarikova R, Kozlovsky J. Anticalcium effect of 4-hydroxypropiophenone derivatives-potential blockers of beta-adrenoceptors (in Slovak). Čes Slov Farm. 1994a;3:226-228.
    Search in Google Scholar
  9. [9] Čižmarikova R, Kozlovsky J. Pharmacological evaluation of 4-hydroxypropiophenone-potential beta-adrenoreceptor blockers (in Slovak). Farm Obzor. 1994b;63:258-260.
    Search in Google Scholar
  10. [10] Čižmarikova R, Račanska E. Beta-adrenergic receptor blockers II. Aryloxyaminopropanols. (Review in Slovak).Farm Obzor. 1998;67:113-117.
    Search in Google Scholar
  11. [11] Čižmarikova R, Polakovičova M, Mišikova E. Synthesis, physicochemical properties and conformational studies of (3-chloromethyl-4-hydroxyphenyl)ethanones. Chem Papers. 2002;56:256-260.
    Search in Google Scholar
  12. [12] Čižmarikova R, Račanska E, Hroboňova K, Lehotay J, Mišikova E. Synthesis and enantioseparation od some aryloxyaminopropanol derivatives and their effect on the central nervous system. Acta Facult Pharm Univ Comenianae. 2003;50:38-50.
    Search in Google Scholar
  13. [13] Čižmarikova R, Nemethy A, Valentova J, Hroboňova K, Bruchata K. Synthesis and HPLC enantioseparation of derivatives of the 3-hydroxyphenylethanone. Acta Facult Pharm Univ Comenianae. 2012;50:38-50.10.2478/v10219-012-0023-7
    Search in Google Scholar
  14. [14] Fornstedt T, Gotmar G, Andersson M, Guiochon G: Dependence on the mobile phase pH of the adsorption behavior of propranolol enantiomers on a cellulase protein used as the chiral selector. J Am Chem Soc. 1999;121:1164-1174.10.1021/ja9831296
    Search in Google Scholar
  15. [15] Fulde K, Frahm AW: Temperature-induced inversion of elution order in the enantioseparation of sotalol on a cellobiohydrolase I-based stationary phase. J Chromatogr A. 1999;858:33-43.10.1016/S0021-9673(99)00798-0
    Search in Google Scholar
  16. [16] Griffith R.K. Adrenergics and adrenergic blocking agents.In Abraham, D.J. Burger/s Medicinal Chemistry and Drug Discovery. Vol.6. Nervous system agents 6th ed New York: John Wiley sons, INC. 2003; p. 1-39.10.1002/0471266949.bmc093
    Search in Google Scholar
  17. [17] Hroboňova K, Lehotay J, Čižmarikova R, Armstrong DW.Study of mechanism of enantioseparation. Part I. Chiral analysis of alkylaminoderivatives of aryloxypropanols by HPLC using macrocyclic antibiotics as chiral selectors. J Liq Chromatogr Rel Technol. 2001;24:2225-2237.10.1081/JLC-100105136
    Search in Google Scholar
  18. [18] Hroboňova K, Lehotay J, Čižmarikova R. HPLC enantioseparation of potential β-blockers of the aryloxyaminopropanol type. Pharmazie. 2004;59:828-832.
    Search in Google Scholar
  19. [19] Kečkešova S, Sedlarova E. Review of the ultrashort-acting beta-adrenergic blockers. (Review in Slovak). Farm Obzor. 2010;79:3-13.
    Search in Google Scholar
  20. [20] Mosti L, Menozzi G, Fossa P et al. Synthesis and preliminary biological evaluation of novel N-substituted 1-amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy] propan-2-ols interesting as potential antiarrhytmic, local anaesthetic and analgesic agent. Arzneim Forsch / Drug Res. 2000;50:963-972.
    Search in Google Scholar
  21. [21] Valentova J, Čižmarikova R, Bui TTT, Drake AF, Hutt AJ.Enantiomeric resolution of novel aryloxyaminopropanol derivatives with β-adrenoceptor antagonist activity on a derivatised amylose chiral stationary. Chromatographia. 2003;11/12:733-740.
    Search in Google Scholar
  22. [22] Wang Z, Ouyang J, Baeyens WRG. Recent development of enantioseparation techniques for adrenergic drugs using liquid chromatography and capillary electrophoresis.A review. J Chromatogr B. 2008;862:1-14.10.1016/j.jchromb.2007.11.03418164252
    Search in Google Scholar
  23. [23] Wang X, Ching BCH. Liquid chromatographic retention behavior and enantiomeric separation of three chiral center β-blocker Drug (Nadolol) using heptakis(6-azido-6-deoxy-2,3-di-O-phenylcarbamolted) β-cyclodextrin.Bonded chiral stationary phase. Chirality. 2002:14:798-805.10.1002/chir.1014112395397
    Search in Google Scholar
  24. [24] Zhang H, Shao H, Youmei A, Zhang Z. Optimized conditions of enantioseparation of β-blockers by CZE, using carboxymethyl β-cyclodextrin as chiral selector. Chromatographia. 2008; 68: 653-658.10.1365/s10337-008-0747-7
    Search in Google Scholar
DOI: https://doi.org/10.2478/afpuc-2013-0023 | Journal eISSN: 2453-6725
Journal RSS Feed
Language: English
Page range: 37 - 42
Published on: Dec 31, 2013
Published by: Comenius University in Bratislava, Faculty of Pharmacy
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
aryloxyaminopropanol - enantioseparation - HPLC - Chirobiotic T - Chiralpak AD
Related subjects:
Pharmacy,
Pharmacy, other

© 2013 Čižmáriková R., Némethy A., Valentová J., Hroboňová K., Adamcová K., published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons License.

Previous articleVolume 60 (2013): Issue 2 (December 2013)Next article