Granulation Tissue-Type Hemangioma (GTH) in the Spleen of a Cat: A First Case Report

Hemangiomas are rarely documented in cats, and to date, granulation tissue-type hemangioma (GTH) has not been reported. This report presents the first known case of GTH in the spleen of a 5-year-old cat, focusing on its histopathological and immunohistochemical characteristics. The lesion exhibited neoplastic vascular proliferation within granulation tissue, accompanied by fibrous tissue proliferation, which complicated the diagnosis. Immunohistochemical staining for von Willebrand factor (VWF) and vimentin confirmed the vascular origin of the cells, distinguishing the lesion from other splenic proliferative diseases. This case expands the diagnostic spectrum of feline splenic vascular tumors and highlights the need for further studies to refine their classification and diagnostic criteria.