Combined shake-flask, chromatographic and in silico approaches for evaluating the physicochemical and ADME properties of aloin A and aloe-emodin Cover

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Combined shake-flask, chromatographic and in silico approaches for evaluating the physicochemical and ADME properties of aloin A and aloe-emodin

Acta Pharmaceutica

Volume 75 (2025): Issue 3 (September 2025)

By: Daniela Amidžić Klarić , Jelena Kovačić , Petra Bajt , Nikša Turk, Željko Krznarić , Emma Riordan and Ana Mornar

Open Access

|Oct 2025

Authors

Daniela Amidžić Klarić

Department of Pharmaceutical Analysis, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

Jelena Kovačić

Department of Pharmaceutical Analysis, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

Petra Bajt

Center for Translational Research and Innovation in Pharmacy, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

Nikša Turk

Department of Gastroenterology, University Hospital Centre, Zagreb, Croatia

Željko Krznarić

Department of Gastroenterology, University Hospital Centre, Zagreb, Croatia

School of Medicine, University of Zagreb, Zagreb, Croatia

Emma Riordan

School of Pharmacy, University College Cork, Cork, Ireland

Ana Mornar

ana.mornar@pharma.unizg.hr

Department of Pharmaceutical Analysis, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

DOI: https://doi.org/10.2478/acph-2025-0014 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075

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Language: English

Page range: 427 - 447

Accepted on: May 10, 2025

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Published on: Oct 10, 2025

Published by: Croatian Pharmaceutical Society

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

ADME properties,

biomimetic chromatography

Related subjects:

Pharmacy, other

© 2025 Daniela Amidžić Klarić, Jelena Kovačić, Petra Bajt, Nikša Turk, Željko Krznarić, Emma Riordan, Ana Mornar, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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