References
- 1. C. Steele, D. Steel and C. Waine, 6 – Pathophysiology of Diabetic Retinopathy, in Diabetes and the Eye (Eds. C. Steele, D. Steel and C. Waine), Butterworth-Heineman 2008, pp. 59–70; https://doi.org/10.1016/B978-0-08-045307-1.50011-310.1016/B978-0-08-045307-1.50011-3
- 2. O. R. Ayepola, N. L. Brooks and O. O. Oguntibeju, Antioxidant-antidiabetic Agents and Human Health, in Oxidative Stress and Diabetic Complications: The Role of Antioxidant Vitamins and Flavonoids, Intech Open, London 2014, pp. 25–58.
- 3. J. L. Ríos, F. Francini and G. T. Schinella, Natural products for the treatment of type 2 diabetes mellitus, Planta Med.81 (2015) 975–994; https://doi.org/10.1055/s-0035-154613110.1055/s-0035-1546131
- 4. A. M. Donia, Phytochemical and pharmacological studies on Scorzonera alexandrina Boiss, J. Saud. Chem. Soc.20 (2016) S433–S439; https://doi.org/10.1016/j.jscs.2013.01.00110.1016/j.jscs.2013.01.001
- 5. L. Milella, A. Bader, N. De Tommasi, D. Russo and A. Braca, Antioxidant and free radical-scavenging activity of constituents from two Scorzonera species, Food Chem.160 (2014) 298–304; https://doi.org/10.1016/j.foodchem.2014.03.09710.1016/j.foodchem.2014.03.097
- 6. Ö. B. Acıkara, G. S. Çitoğlu, S. Dall’Acqua, H. Özbek, J. Cvačka, M. Zemlička and K. Ŝmejkal, Bioassay-guided isolation of the antinociceptive compounds motiol and β-sitosterol from Scorzonera latifolia root extract, Pharmazie69 (2014) 711–714; https://doi.org/10.1691/ph.2014.3920
- 7. E. K. Akkol, Ö. B. Acıkara, I. Süntar, B. Ergene and G. Saltan Çitoğlu, Ethnopharmacological evaluation of some Scorzonera species: In vivo anti-inflammatory and antinociceptive effects, J. Ethnopharmacol.140 (2012) 261–270; https://doi.org/10.1016/j.jep.2012.01.01510.1016/j.jep.2012.01.015
- 8. E. K. Akkol, O. B. Acıkara, I. Süntar, G. Saltan Çitoğlu, H. Keleş and B. Ergene, Enhancement of wound healing by topical application of Scorzonera species: Determination of the constituents by HPLC with new validated reverse phase method, J. Ethnopharmacol. 137 (2011) 1018–1027; https://doi.org/10.1016/j.jep.2011.07.02910.1016/j.jep.2011.07.029
- 9. Association of Official Analytical Chemists, Official Methods of Analysis of the AOAC International, (Ed. G. W. Latimer), 20th ed., AOAC International, Rockville 2016, pp. 570–655.
- 10. V. L. Singleton, R. Orthofer and R. M. Lamuela-Raventós, Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent, Methods Enzymol. 299 (1999) 152–178; https://doi.org/10.1016/S0076-6879(99)99017-110.1016/S0076-6879(99)99017-1
- 11. J. Zhishen, T. Mengcheng and W. Jianming, The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals, Food Chem. 64 (1999) 555–559; https://doi.org/10.1016/S0308-8146(98)00102-210.1016/S0308-8146(98)00102-2
- 12. K. Mishra, H. Ojha and N. K. Chaudhury, Estimation of antiradical properties of antioxidants using DPPH• assay: A critical review and results, Food Chem. 130 (2012) 1036–1043; https://doi.org/10.1016/j.foodchem.2011.07.12710.1016/j.foodchem.2011.07.127
- 13. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans, Antioxidant activity applying an improved ABTS radical cation decolorization assay, Free Radic. Biol. Med. 26 (1999) 1231–1237; https://doi.org/10.1016/S0891-5849(98)00315-310.1016/S0891-5849(98)00315-3
- 14. Y. M. Kim, Y. K. Jeong, M. H. Wang, W. Y. Lee and H. I. Rhee, Inhibitory effect of pine extract on α-glucosidase activity and postprandial hyperglycemia, Nutrition21 (2005) 756–761; https://doi.org/10.1016/j.nut.2004.10.01410.1016/j.nut.2004.10.014
- 15. H. H. Draper and M. Hadley, Malondialdehyde determination as index of lipid peroxidation, Methods Enzymol. 186 (1990) 421–431; https://doi.org/10.1016/0076-6879(90)86135-I10.1016/0076-6879(90)86135-I
- 16. E. Beutler, T. Gelbart and C. Pegelow, Erythrocyte glutathione synthetase deficiency leads not only to glutathione but also to glutathione-S-transferase deficiency, J. Clin. Invest.77 (1986) 38–41; https://doi.org/10.1172/JCI11229810.1172/JCI112298
- 17. J. M. McCord, Analysis of superoxide dismutase activity, Curr. Protoc. Toxicol. 00 (1999) 7.3.1–7.3.9; https://doi.org/10.1002/0471140856.tx0703s0010.1002/0471140856.tx0703s00
- 18. W. A. Günzler, H. Kremers and L. Flohé, An improved coupled test procedure for glutathione peroxidase (EC 1-11-1-9-) in blood, Z. Klin. Chem. Klin. Biochem. 12 (1974) 444–448; https://doi.org/10.1515/cclm.1974.12.10.444.10.1515/cclm.1974.12.10.444
- 19. H. Aebi, Catalase in vitro, Methods Enzymol. 105 (1984) 121–126; https://doi.org/10.1016/S0076-6879(84)05016-310.1016/S0076-6879(84)05016-3
- 20. Ö. Erel, A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation, Clin. Biochem. 37 (2004) 277–285; https://doi.org/10.1016/j.clinbiochem.2003.11.01510.1016/j.clinbiochem.2003.11.01515003729
- 21. Ö. Erel, A new automated colorimetric method for measuring total oxidant status, Clin. Biochem. 38 (2005) 1103–1111; https://doi.org/10.1016/j.clinbiochem.2005.08.00810.1016/j.clinbiochem.2005.08.00816214125
- 22. O. B. Acikara, J. Hošek, P. Babula, J. Cvačka, M. Budešínský, M. Dračinský, G. S. İşcan, D. Kadlecová, L. Ballová and K. Šmejkal, Turkish Scorzonera species extracts attenuate cytokine secretion via inhibition of NF-κB activation, showing anti-inflammatory effect in vitro, Molecules21 (2016) Article ID 43 (14 pages); https://doi.org/10.3390/molecules2101004310.3390/molecules21010043627453826729082
- 23. S. Dall’Acqua, G. Ak, S. Sut, I. Ferrarese, G. Zengin, E. Yıldıztugay, M. F. Mahomoodally, K. I. Sinan, and D. Lobine, Phenolics from Scorzonera tomentosa L.: Exploring the potential use in industrial applications via an integrated approach, Ind. Crops Prod. 154 (2020) 112751–112760; https://doi.org/10.1016/j.indcrop.2020.11275110.1016/j.indcrop.2020.112751
- 24. Institute of Medicine, Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, The National Academies Press, Washington DC 2006, pp. 286–402; https://doi.org/10.17226/1153710.17226/11537
- 25. F. Taranto, A. Pasqualone, G. Mangini, P. Tripodi, M. M. Miazzi, S. Pavan and C. Montemurro, Polyphenol oxidases in crops: Biochemical, physiological and genetic aspects, Int. J. Mol. Sci. 18 (2017) 377–393; https://doi.org/10.3390/ijms1802037710.3390/ijms18020377534391228208645
- 26. R. Khattaba, G. B. Celli, A. Ghanem and M. S. Brooks, Effect of frozen storage on polyphenol content and antioxidant activity of haskap berries (Lonicera caerulea L.), J. Berry Res. 5 (2015) 231–242; https://doi.org/10.3233/JBR-15010510.3233/JBR-150105
- 27. K. T. Kongstad, C. Ozdemir, A. Barzak, S. G. Wubshet and D. Staerk, Combined use of high-resolution α-glucosidase inhibition profiling and high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance spectroscopy for investigation of antidiabetic principles in crude plant extracts, J. Agric. Food Chem. 63 (2015) 2257–2263; https://doi.org/10.1021/jf506297k10.1021/jf506297k25652946
- 28. D. Bagdas, B. C. Etoz, Z. Gul, S. Ziyanok, S. Inan, O. Turacozen, N. Y. Gul, A. Topal, N. Cinkilic, S. Tas, M. O. Ozyigit and M. S. Gurun, In vivo systemic chlorogenic acid therapy under diabetic conditions: Wound healing effects and cytotoxicity/genotoxicity profile, Food Chem. Toxicol. 81 (2015) 54–61; https://doi.org/10.1016/j.fct.2015.04.00110.1016/j.fct.2015.04.00125846499
- 29. W. Blaschek, Natural products as lead compounds for sodium glucose cotransporter (SGLT) inhibitors, Planta Med. 83 (2017) 985–993; https://doi.org/10.1055/s-0043-10605010.1055/s-0043-10605028395363
- 30. C. Schulze, A. Bangert, G. Kottra, K. E. Geillinger, B. Schwanck, H. Vollert, W. Blaschek and H. Daniel, Inhibition of the intestinal sodium-coupled glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood glucose levels in mice and humans, Mol. Nutr. Food Res. 58 (2014) 1795–1808; https://doi.org/10.1002/mnfr.20140001610.1002/mnfr.20140001625074384
- 31. S. Meng, J. Cao, Q. Feng, J. Peng and Y. Hu, Roles of chlorogenic acid on regulating glucose and lipids metabolism: A review, Evid-Based Complement. Alternat. Med. 2013 (2013) Article ID 801457 (11 pages); https://doi.org/10.1155/2013/80145710.1155/2013/801457376698524062792
- 32. V. R. Punithavathi, P. S. M. Prince, R. Kumar and J. Selvakumari, Antihyperglycaemic, antilipid peroxidative and antioxidant effects of gallic acid on streptozotocin induced diabetic Wistar rats, Eur. J. Pharmacol. 650 (2011) 465–471; https://doi.org/10.1016/j.ejphar.2010.08.05910.1016/j.ejphar.2010.08.05920863784
- 33. A. Bashta, N. Ivchuk and O. Bashta, Yacón and Scorzonera as functional enrichment of food, Ukrainian J. Food Sci. 3 (2015) 13–22.
- 34. N. Petkova, Characterization of inulin from black salsify (Scorzonera hispanica L.) for food and pharmaceutical purposes, Asian J. Pharm. Clin. Res. 11 (2018) 221–225; https://doi.org/10.22159/ajpcr.2018.v11i12.2826210.22159/ajpcr.2018.v11i12.28262
- 35. M. Rao, C. Gao, L. Xu, L. Jiang, J. Zhu, G. Chen, B. Y. K. Law and Y. Xu, Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: A systematic review and meta-analysis, J. Diabetes Res. 2019 (2019) Article ID 5101423 (13 pages); https://doi.org/10.1155/2019/510142310.1155/2019/5101423673264231534973
- 36. P. I. Ingaramo, M. T. Ronco, D. E. A. Francés, J. A. Monti, G. B. Pisani, M. P. Ceballos, M. Galleano, M. C. Carrillo and C. E. Carnovale, Tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus, Mol. Immunol. 48 (2011) 1397–1407; https://doi.org/10.1016/j.molimm.2011.03.01510.1016/j.molimm.2011.03.01521481476
- 37. T. Zhang, Y. Xie, Z. Zhang and G. Wang, Study on hepatoprotective effects of total flavonoids in Scorzonera austriaca Wild in vivo and in vitro, Chin. J. Biochem. Pharm. 35 (2015) 6–9.
- 38. F. K. Lutchmansingh, J. W. Hsu, F. I. Bennett, A. V. Badaloo, N. McFarlane-Anderson, G. M. Gordon-Strachan, R. A. Wright-Pascoe, F. Jahoor and M. S. Boyn, Glutathione metabolism in type 2 diabetes and its relationship with microvascular complications and glycemia, PLoS ONE13 (2018) e0198626 (12 pages); https://doi.org/10.1371/journal.pone.019862610.1371/journal.pone.0198626599167929879181
- 39. L. J. Yan, Redox imbalance stress in diabetes mellitus: Role of the polyol pathway, Animal Model Exp. Med. 1 (2018) 7–13; https://doi.org/10.1002/ame2.1200110.1002/ame2.12001597537429863179
- 40. H. Yang and C. Zeng, Effects of water extract from Scorzonera sinensis Lipsch, Pteridium aquilinum and Sonchus oleraceus L. on plasma-lipids metabolism in mice fed high fats diet, Food Res. Dev. 36 (2015) 11–13; https://doi.org/10.3969/j.issn.1005-6521.2015.06.003