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Preparation, characterization, and in vivo pharmacokinetics of thermosensitive in situ nasal gel of donepezil hydrochloride Cover

Preparation, characterization, and in vivo pharmacokinetics of thermosensitive in situ nasal gel of donepezil hydrochloride

Open Access
|Feb 2020

References

  1. 1. C. A. Lane, J. Hardy and J. M. Schott, Alzheimer’s disease, Eur. J. Neurol. 25 (2018) 59–70; https://doi.org/10.1111/ene.1343910.1111/ene.1343928872215
  2. 2. L. A. Craig, N. S. Hong and R. J. McDonald, Revisiting the cholinergic hypothesis in the development of Alzheimer’s disease, Neurosci. Biobehav. Rev.35 (2011) 1397–1409; https://doi.org/10.1016/j.neubiorev.2011.03.00110.1016/j.neubiorev.2011.03.00121392524
  3. 3. T. Maurice, Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments, Behav. Brain Res. 296 (2016) 270–278; https://doi.org/10.1016/j.bbr.2015.09.02010.1016/j.bbr.2015.09.02026386305
  4. 4. K. Meguro, M. Kasai, M. Meguro, H. Ishii and S. Yamaguchi, Donepezil and life expectancy in Alzheimer’s disease: A retrospective analysis in the Tajiri Project, BMC Neurol. 14 (2014) 83; https://doi.org/10.1186/1471-2377-14-8310.1186/1471-2377-14-83399719524720852
  5. 5. E. Garcia-Garcia, K. Andrieux, S. Gil and P. Couvreur, Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain? Int. J. Pharm. 298 (2005) 274–292; https://doi.org/10.1016/j.ijpharm.2005.03.03110.1016/j.ijpharm.2005.03.03115896933
  6. 6. C. V. Pardeshi and V. S. Belgamwar, Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood-brain barrier: an excellent platform for brain targeting, Expert Opin. Drug Del. 10 (2013) 957–972; https://doi.org/10.1517/17425247.2013.79088710.1517/17425247.2013.79088723586809
  7. 7. M. Agrawal, S. Saraf, S. Saraf, S. G. Antimisiaris, M. B. Chougule, S. A. Shoyele and A. Alexander, Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs, J. Control. Release281 (2018) 139–177; https://doi.org/10.1016/j.jconrel.2018.05.01110.1016/j.jconrel.2018.05.01129772289
  8. 8. C. Christodoulou, P. Melville, W. F. Scherl, W. S. Macallister, L. E. Elkins and L. B. Krupp, Effects of donepezil on memory and cognition in multiple sclerosis, J. Neurol. Sci.245 (2006) 127–136; https://doi.org/10.1016/j.jns.2005.08.02110.1016/j.jns.2005.08.02116626752
  9. 9. L. C. Espinoza, M. Vacacela, B. Clares, M. L. Garcia, M. J. Fabrega and A. C. Calpena, Development of a nasal donepezil-loaded microemulsion for the treatment of Alzheimer’s disease: in vitro and ex vivo characterization, CNS Neuro. Disord. Drug Targets17 (2018) 43–53; https://doi.org/10.2174/187152731766618010412234710.2174/187152731766618010412234729299992
  10. 10. Bhavna, Shadab Md, M. Ali, R. Ali, A. Bhatnagar, S. Baboota and J. Ali, Donepezil nanosuspension intended for nose to brain targeting: In vitro and in vivo safety evaluation, Int. J. Biol. Macromol. 67 (2014) 418–425; https://doi.org/10.1016/j.ijbiomac.2014.03.02210.1016/j.ijbiomac.2014.03.02224705169
  11. 11. A. K. Al Asmari, Z. Ullah, M. Tariq and A. Fatani, Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil, Drug Des. Devel. Ther. 10 (2016) 205–215; https://doi.org/10.2147/DDDT.S9393710.2147/DDDT.S93937
  12. 12. S. Al Harthi, S. E. Alavi, M. A. Radwan, M. M. El Khatib and I. A. Al Sarra, Nasal delivery of donepezil HCl-loaded hydrogels for the treatment of Alzheimer’s disease, Sci. Rep. 9 (2019) 9563; https://doi.org/10.1038/s41598-019-46032-y10.1038/s41598-019-46032-y
  13. 13. C. Karavasili and D. G. Fatouros, Smart materials: in situ gel-forming systems for nasal delivery, Drug Discov. Today21 (2016) 157–166; https://doi.org/10.1016/j.drudis.2015.10.01610.1016/j.drudis.2015.10.016
  14. 14. J. C. Gilbert, J. Hadgraft, A. Bye and L. G. Brookes, Drug release from Pluronic F-127 gels, Int. J. Pharm. 32 (1986) 223–228; https://doi.org/10.1016/0378-5173(86)90182-110.1016/0378-5173(86)90182-1
  15. 15. L. E. Jabarian, M. R. Rouini, F. Atyabi, A. Foroumadi, S. M. Nassiri and R. Dinarvand, In vitro and in vivo evaluation of an in situ gel forming system for the delivery of PEGylated octreotide, Eur. J. Pharm. Sci. 48 (2013) 87–96; https://doi.org/10.1016/j.ejps.2012.09.01710.1016/j.ejps.2012.09.017
  16. 16. Y. C. Li, H. Xin and L. Gao, To establish an HPLC-ESI-SIM method for the determination of done-pezil in human plasma, Chin. J. Aesthetic Med.21 (2012) 24–26; https://doi.org/10.15909/j.cnki.cn61-1347/r.2012.16.451
  17. 17. M. Valis, J. Masopust, O. Vysata, J. Hort, R. Dolezal, J. Tomek, J. Misik, K. Kuca and J. Z. Karasova, Concentration of donepezil in the cerebrospinal fluid of AD Patients: Evaluation of dosage sufficiency in standard treatment strategy, Neurotox. Res. 31 (2017) 162–168; https://doi.org/10.1007/s12640-016-9672-y10.1007/s12640-016-9672-y
  18. 18. U. C. Galgatte, A. B. Kumbhar and P. D. Chaudhari, Development of in situ gel for nasal delivery: design, optimization, in vitro and in vivo evaluation, Drug Deliv.21 (2014) 62–73; https://doi.org/10.3109/10717544.2013.84977810.3109/10717544.2013.849778
  19. 19. H. M. Fan, Z. X. Cong and F. G. Gu, Preparation and in vitro properties of thermosensitive in situ nasal gel of donepezil hydrochloride, Centr. South Pharm. 16 (2018) 1194–1199; https://doi.org/10.7539/j.issn.1672-2981.2018.09.003 (in Chinese only)
  20. 20. Q. Wang, Z. Zuo, C. K. C. Cheung and S. S. Y. Leung, Updates on thermosensitive hydrogel for nasal, ocular and cutaneous delivery, Int. J. Pharm.559 (2019) 86–101; https://doi.org/10.1016/j.ijpharm.2019.01.03010.1016/j.ijpharm.2019.01.030
  21. 21. C. R. Behl, H. K. Pimplaskar, A. P. Sileno, J. deMeireles and V. D. Romeo, Effects of physicochemical properties and other factors on systemic nasal drug delivery, Adv. Drug Deliv. Rev. 29 (1998) 89–116; https://doi.org/10.1016/s0169-409x(97)00063-x10.1016/S0169-409X(97)00063-X
DOI: https://doi.org/10.2478/acph-2020-0032 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 411 - 422
Accepted on: Nov 18, 2019
Published on: Feb 17, 2020
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
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© 2020 Fugen Gu, Huimin Fan, Zhixin Cong, Shuang Li, Yi Wang, Chunzhi Wu, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.