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Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway Cover

Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway

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Open Access
|Feb 2020

References

  1. 1. X. F. Li, A. M. Zang, Y. C. Jia, J. C. Zhang, W. F. Fan, J. Feng, M. D. Duan, L. Zhang, R. Huo, J. Jiao and X. W. Zhu, Triptolide reduces proliferation and enhances apoptosis of human non-small cell lung cancer cells through PTEN by targeting miR-21, Mol. Med. Rep. 13 (2016) 2763–2768; https://doi:10.3892/mmr.2016.484410.3892/mmr.2016.4844
  2. 2. H. Han, Y. Chen, L. Cheng, E. V. Prochownik and Y. Li, microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13, Oncotarget7 (2016) 16409–16419; https://doi:10.18632/oncotarget.765310.18632/oncotarget.7653
  3. 3. F. Gao, H. Wu, R. Wang, Y. Guo, Z. Zhang, T. Wang, G. Zhang, C. Liu and J. Liu, MicroRNA-485-5p suppresses the proliferation, migration and invasion of small cell lung cancer cells by targeting flotillin-2, Bioengineered10 (2019) 1–12; https://doi:10.1080/21655979.2019.158605610.1080/21655979.2019.1586056
  4. 4. Z. G. Wang, L. M. Liu, X. F. Guo, C. M. Guo and W. X. Wang, microRNA-1236-3p Regulates DDP Resistance in Lung Cancer Cells, Open Med. (Wars). 14 (2019) 41–51; https://doi:10.1515/med-2019-000710.1515/med-2019-0007
  5. 5. Q. Y. Chen, D. M. Jiao, J. Wang, H. Z. Hu, X. L. Tang, J. Chen, H. Mou and W. Lu, miR-206 regulates cisplatin resistance and EMT in human lung adenocarcinoma cells partly by targeting MET, Oncotarget7 (2016) 24510–24526; https://doi:10.18632/oncotarget.1297210.18632/oncotarget.12972
  6. 6. Q. Y. Chen, Y. Zheng, D. M. Jiao, F. Y. Chen, H. Z. Hu, Y. Q. Wu, J. Song, J. Yan, L. J. Wu and G. Y. Lv, Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway, J. Nutr. Biochem. 25 (2014) 177–185; https://doi:10.1016/j.jnutbio.2013.10.00410.1016/j.jnutbio.2013.10.004
  7. 7. T. Yu, J. C. Li, Y. Qiu and H. Sun, 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation, Mol. Cell Biochem. 361 (2012) 47–54; https://doi:10.1007/s11010-011-1086-910.1007/s11010-011-1086-9
  8. 8. H. Jin, F. Qiao, Y. Wang, Y. D. Xu and Y. Shang, Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway, Oncol. Rep. 34 (2015) 2782–2789; https://doi:10.3892/or.2015.425810.3892/or.2015.4258
  9. 9. Z. R. Qiang, L. Y. Meng, C. X. Yi, L. Y. Yu, W. X. Chen and W. H. Sha, Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells, J. Int. Med. Res. 47 (2019) 1288–1297; https://doi:10.1177/030006051882221310.1177/0300060518822213
  10. 10. Y. P. Li, W. X. Sun, N. Han, Y. Zou and D. X. Yin, Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway, BMC Cancer. 18 (2018) 1230; https://doi:10.1186/s12885-018-5130-y10.1186/s12885-018-5130-y
  11. 11. M. X. Ye, J. Zhang, J. Zhang, Q. Miao, L. B. Yao and J. Zhang, Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer, Cancer Lett. 357 (2015) 196–205; https://doi:10.1016/j.canlet.2014.11.02810.1016/j.canlet.2014.11.028
  12. 12. Y. Panahi, B. Darvishi, M. Ghanei, N. Jowzi, F. Beiraghdar and B. S. Varnamkhasti, Molecular mechanisms of curcumins suppressing effects on tumorigenesis, angiogenesis and metastasis, focusing on NF-κB pathway, Cytokine Growth Factor Rev. 28 (2016) 21–29; https://doi:10.1016/j.cytogfr.2015.12.00410.1016/j.cytogfr.2015.12.004
  13. 13. T. Zhang, Y. Chen, Y. Ge, Y. Hu, M. Li and Y. Jin, Inhalation treatment of primary lung cancer using liposomal curcumin dry powder inhalers, Acta Pharm Sin. 8 (2018) 440–448; https://doi:10.1016/j.apsb.2018.03.00410.1016/j.apsb.2018.03.004
  14. 14. J. Yuan, R. Liu, Y. Ma, Z. Zhang and Z. Xie, Curcumin attenuates airway inflammation and airway remolding by inhibiting NF-κB signaling and COX-2 in cigarette smoke-induced COPD mice, Inflammation41 (2018) 1804–1814; https://doi:10.1007/s10753-018-0823-610.1007/s10753-018-0823-6
  15. 15. D. Bandyopadhyay, Farmer to pharmacist: curcumin as an anti-invasive and antimetastatic agent for the treatment of cancer, Front Chem. 2 (2014) 113; https://doi:10.3389/fchem.2014.0011310.3389/fchem.2014.00113
  16. 16. L. Mühlberg, B. Kühnemuth, E. Costello, V. Shaw, B. Sipos, M. Huber, H. Griesmann, S. Krug, M. Schober, T. M. Gress and P. Michl, miRNA dynamics in tumor-infiltrating myeloid cells modulating tumor progression in pancreatic cancer, Oncoimmunology5 (2016) e1160181; https://doi:10.1080/2162402X.2016.116018110.1080/2162402X.2016.1160181
  17. 17. C. C. Sun, Z. D. Liu, S. J. Li, C. L. Yang, R. L. Xue, Y. Y. Xi, L. Wang, S. Q. Wang, Q. Q. He, J. Huang, S. P. Xie, W. Y. Jiang and D. J. Li, Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation, Oncotarget. 6 (2015) 25533–25574; https://doi:10.18632/oncotarget.457510.18632/oncotarget.4575
  18. 18. C. R. Zito, L. B. Jilaveanu, V. Anagnostou, D. Rimm, G. Bepler, S. M. Maira, W. Hackl, R. Camp, H. M. Kluger and H. H. Chao, Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells, PLoS One. 7 (2012) e31331; https://doi:10.1371/journal.pone.003133110.1371/journal.pone.0031331
  19. 19. Q. Yu, B. Zhao, Q. He, Y. Zhang and X. B. Peng, microRNA-206 is required for osteoarthritis development through its effect on apoptosis and autophagy of articular chondrocytes via modulating the phosphoinositide 3-kinase/protein kinase B-mTOR pathway by targeting insulin-like growth factor-1, J. Cell Biochem.120 (2019) 5287–5303; https://doi:10.1016/j.jphs.2018.02.00310.1016/j.jphs.2018.02.003
  20. 20. D. Xue, Y. Yang, Y. W. Liu, P. W. Wang, Y. Dai, Q. Q. Liu, L. J. Chen, J. Shen, H. Y. Ju, Y. Li, and Z. G. Tan, MicroRNA-206 attenuates the growth and angiogenesis in non-small cell lung cancer cells by blocking the 14-3-3ζ/STAT3/HIF-1α/VEGF signaling, Oncotarget7 (2016) 79805–79813; https://doi:10.18632/oncotarget.822910.18632/oncotarget.8229
DOI: https://doi.org/10.2478/acph-2020-0029 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 399 - 409
Accepted on: Sep 12, 2019
Published on: Feb 17, 2020
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
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© 2020 Naizhi Wang, Tao Feng, Xiaona Liu, Qin Liu, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.