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AKR1D1*36 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers – a pilot study in healthy volunteers Cover

AKR1D1*36 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers – a pilot study in healthy volunteers

Acta Pharmaceutica
Volume 69 (2019): Issue 3 (September 2019)
By: Aleksandra Kapedanovska Nestorovska,  Krume Jakjovski,  Zorica Naumovska,  Zoran Sterjev,  Nadica Matevska Geskovska,  Kristina Mladenovska,  Ljubica Suturkova and  Aleksandar Dimovski  
Open Access
|Jun 2019

Authors

Aleksandra Kapedanovska Nestorovska

alka@ff.ukim.edu.mk

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Krume Jakjovski

Department of Preclinical and Clinical Pharmacology and Toxicology, Faculty of Medicine, University Ss Cyril and Methodius, Skopje

Zorica Naumovska

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Zoran Sterjev

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Nadica Matevska Geskovska

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Kristina Mladenovska

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Ljubica Suturkova

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje

Aleksandar Dimovski

Center for Biomolecular and Pharmaceutical Analysis, Faculty of Pharmacy, University Ss Cyril and Methodius, Skopje
Research Center for Genetic Engineering and Biotechnology, “Georgi D. Efremov” Macedonian Academy of Sciences and Arts, Skopje
DOI: https://doi.org/10.2478/acph-2019-0032 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 399 - 412
Accepted on: Feb 18, 2019
Published on: Jun 26, 2019
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
ibuprofen,
enantiomers,
pharmacokinetics,
AKR1D1,
CYP2C9,
pharmacogenetics
Related subjects:
Pharmacy,
Pharmacy, other

© 2019 Aleksandra Kapedanovska Nestorovska, Krume Jakjovski, Zorica Naumovska, Zoran Sterjev, Nadica Matevska Geskovska, Kristina Mladenovska, Ljubica Suturkova, Aleksandar Dimovski, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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