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Metabolic stability and its role in the discovery of new chemical entities Cover

Metabolic stability and its role in the discovery of new chemical entities

Acta Pharmaceutica
Volume 69 (2019): Issue 3 (September 2019)
By: Karolina Słoczyńska,  Agnieszka Gunia-Krzyżak,  Paulina Koczurkiewicz,  Katarzyna Wójcik-Pszczoła,  Dorota Żelaszczyk,  Justyna Popiół and  Elżbieta Pękala  
Open Access
|Jun 2019

Authors

Karolina Słoczyńska

karolina.sloczynska@uj.edu.pl

Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Agnieszka Gunia-Krzyżak

Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Paulina Koczurkiewicz

Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Katarzyna Wójcik-Pszczoła

Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Dorota Żelaszczyk

Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Justyna Popiół

Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland

Elżbieta Pękala

Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland
DOI: https://doi.org/10.2478/acph-2019-0024 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 345 - 361
Accepted on: Dec 29, 2018
Published on: Jun 26, 2019
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
metabolic stability,
biotransformation,
intrinsic clearance,
half-life,
metabolites,
new chemical entity
Related subjects:
Pharmacy,
Pharmacy, other

© 2019 Karolina Słoczyńska, Agnieszka Gunia-Krzyżak, Paulina Koczurkiewicz, Katarzyna Wójcik-Pszczoła, Dorota Żelaszczyk, Justyna Popiół, Elżbieta Pękala, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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