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High-performance liquid chromatography and derivative spectrophotometry for simultaneous determination of pravastatin and fenofibrate in the dosage form Cover

High-performance liquid chromatography and derivative spectrophotometry for simultaneous determination of pravastatin and fenofibrate in the dosage form

Acta Pharmaceutica
Volume 64 (2014): Issue 4 (December 2014)
By: Mohamed M. Hefnawy,  Mostafa S. Mohamed,  Mohammed A. Abounassif,  Amer M. Alanazi and  Gamal A. E. Mostafa  
Open Access
|Dec 2014

References

  1. 1. A. A. Al-Badr and G. A. E. Mostafa, Pravastatin sodium, Comprehensive Profile, Prof. Drug Subst. Exc. Rel. Meth. 39 (2014) 433-513.
    Search in Google Scholar
  2. 2. M. Farnier, Pravastatin and fenofibrate in combination (Pravafenix®) for the treatment of high-risk patients with mixed hyperlipidemia, Expert Rev. Cardiovasc. Ther. 11 (2013) 253-254; DOI: 10.1586/ erc.12.191.10.1586/erc.13.8
    Search in Google Scholar
  3. 3. S. Bauer, J. Mwinyi, A. Stoeckle, T. Gerloff and I. Roots, Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detection, J. Chromatogr. B 818 (2005) 257-262; DOI: 10.1016/j.jchromb.2005.01.006.10.1016/j.jchromb.2005.01.006
    Search in Google Scholar
  4. 4. T. D. Silva, M. A. Oliveira, R. B. de Oliveira and C. D. Vianna-Soares, Development and validation of a simple and fast HPLC method for determination of lovastatin, pravastatin and simvastatin, J. Chromatogr. Sci. 50 (2012) 831-838; DOI: 10.1093/chromsci/bms079.10.1093/chromsci/bms079
    Search in Google Scholar
  5. 5. R. Siekmeier, W. Gross and W. März, Determination of pravastatin by high performance liquid chromatography, Int. J. Clin. Pharmacol. Ther. 38 (2000) 419-425.10.5414/CPP38419
    Search in Google Scholar
  6. 6. H. Vlčková, M. Rabatinová, A. Mikšová, G. Kolouchová, S. Mičuda, P. Solich and L. Nováková, Determination of pravastatin and pravastatin lactone in rat plasma and urine using UHPLC-MS/ MS and microextraction by packed sorbent, Talanta 90 (2012) 22-29; DOI: 10.1016/j.talanta.2011.12.043.10.1016/j.talanta.2011.12.043
    Search in Google Scholar
  7. 7. Z. Zhu and L. Neirinck, High-performance liquid chromatography coupled with negative ion tandem mass spectrometry for determination of pravastatin in human plasma, J. Chromatogr. B 783 (2003) 133-140; DOI: 10.1016/S1570-0232(02)00526-3.10.1016/S1570-0232(02)00526-3
    Search in Google Scholar
  8. 8. D. Mulvana, M. Jemal and S. C. Pulver, Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS, J. Pharm. Biomed. Anal. 23 (2000) 851-866, DOI: 10.1016/S0731-7085(00)00372-1.10.1016/S0731-7085(00)00372-1
    Search in Google Scholar
  9. 9. K. Kawabata, N. Matsushima and K. Sasahara, An automated method for the simultaneous determination of pravastatin and its main metabolite in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry, Biomed. Chromatogr. 12 (1998) 271-275; DOI: 10.1002/(SICI)1099-0801(199809/10)12:5 < 27.
    Search in Google Scholar
  10. 10. B. Nigović, Electrochemical properties and square-wave voltammetric determination of pravastatin, Anal. Bioanal. Chem. 384 (2006) 431-437.10.1007/s00216-005-0188-116341509
    Search in Google Scholar
  11. 11. United States Pharmacopoeia 30, USP Convention Inc., Rockville, 2007.
    Search in Google Scholar
  12. 12. British Pharmacopoeia 2004, The Stationary Office, London 2004, p. 639.
    Search in Google Scholar
  13. 13. R. J. Straka, R. T. Burkhardt and J. E. Fisher, Determination of fenofibric acid concentrations by HPLC after anion exchange solid-phase extraction from human serum, Ther. Drug Monit. 29 (2007) 197-202; DO I: 10.1097/ftd.0b013e318030860a.10.1097/ftd.0b013e318030860a17417074
    Search in Google Scholar
  14. 14. A. A. Kadav and D. N. Vora, Stability indicating UPLC method for simultaneous determination of atorvastatin, fenofibrate and their degradation products in tablets, J. Pharm. Biomed. Anal. 48 (2008) 120-126; DOI: 10.1016/j.jpba.2008.05.018.10.1016/j.jpba.2008.05.01818583084
    Search in Google Scholar
  15. 15. D. Bhavesh, S. Shah and Shivprakash, Determination of fenofibric acid in human plasma by ultra performance liquid chromatography-electrospray ionization mass spectrometry: application to a bioequivalence study, Biomed. Chromatogr. 23 (2009) 922-928, DOI: 10.1002/bmc.1203.10.1002/bmc.120319353730
    Search in Google Scholar
  16. 16. C. Yardimci and N. Ozaltin, Electrochemical studies and square-wave voltammetric determination of fenofibrate in pharmaceutical formulations, Anal. Bioanal. Chem. 378 (2004) 495-498; DOI: 10.1007/s00216-003-2246-x.10.1007/s00216-003-2246-x14564444
    Search in Google Scholar
  17. 17. M. A. Korany, I. I. Hewala and K. M. Abdel-Hay, Determination of etofibrate, fenofibrate, and atorvastatin in pharmaceutical preparations and plasma using differential pulse polarographic and square wave voltammetric techniques, J AOAC Int. 91 (2008) 1051-1058.10.1093/jaoac/91.5.1051
    Search in Google Scholar
  18. 18. P. D. Anumolu, N. S. Bhavani, P. S. Babu and C. Sburahmanyam, A validated spectral discriminating derivative spectrophotometric method for simultaneous quantification of atorvastatin calcium and fenofibrate combination in tablets, Orint. J. Chem. 29 (2013) 1605-1610, DOI: 10.13005/ ojc/290444.10.13005/ojc/290444
    Search in Google Scholar
  19. 19. A. Patel, C. Macwana, V. Pamar and S. Patel, Simultaneous determination of atorvastatin calcium, ezetimibe, and fenofibrate in tablet formulation by HPLC, JAOAC 95 (2012) 419-423.10.5740/jaoacint.1-09522649929
    Search in Google Scholar
  20. 20. International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Harmonised Tripartite Guideline, Validation of Analytical Procedures: Text and Methodology Q2 (R1), ICH Complementary Guideline on Methodology dated 06 November 1996, incorporated in November 2005, London.
    Search in Google Scholar
  21. 21. FDA Guidance for Industry: Bioanalytical Method Validation, US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER ), Center for Biologics Evaluation and Research (CBER), Rockville (MD) 2001.
    Search in Google Scholar
  22. 22. J. N. Miller and J. C. Miller, Statistics and Chemometrics for Analytical Chemistry, 2nd ed., Pearson Education Limited, Harlow 2005.
    Search in Google Scholar
DOI: https://doi.org/10.2478/acph-2014-0039 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 433 - 446
Accepted on: Sep 22, 2014
Published on: Dec 20, 2014
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
pravastatin,
fenofibrate,
spectrophotometry,
HPLC,
dosage form
Related subjects:
Pharmacy,
Pharmacy, other

© 2014 Mohamed M. Hefnawy, Mostafa S. Mohamed, Mohammed A. Abounassif, Amer M. Alanazi, Gamal A. E. Mostafa, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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