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Novel Ethyl 1,5-Disubstituted-1H-Pyrazole-3-Carboxylates as a New Class of Antimicrobial Agents Cover

Novel Ethyl 1,5-Disubstituted-1H-Pyrazole-3-Carboxylates as a New Class of Antimicrobial Agents

Open Access
|Oct 2014

References

  1. 1. N. D. Gaikwad, S. V. Patil and V. D. Bobade, Synthesis and antimicrobial activity of novel thiazole substituted pyrazole derivatives, J. Het. Chem. 50 (2013) 519-527; DOI: 10.1002/jhet.1513.
  2. 2. M. S. Essam and M. M. H Nagwa, Synthesis and antimicrobial evaluation of some pyrazole derivatives, Molecules 17 (2012) 4962-4971; DOI: 10.3390/molecules17054962.
  3. 3. Z. Chuan-Yu, L. Xing-Hai, W. Bao-Lei, W. Su-Hua and L. Zheng-Ming, Synthesis and antifungal activities of new pyrazole derivatives via 1,3-dipolar cycloaddition reaction, Chem. Biol. Drug Des. 75 (2010) 489-493; DOI: 10.1111/j.1747-0285.2010.00948.x.
  4. 4. E. M. Flefel, W. A. Tantawy, W. A. El-Sayed, H. H. Sayed and N. M. Fathy, Synthesis and anticancer activity of new substituted pyrazoles and their derived 1,2,4-triazoles and sugar derivatives, J. Het. Chem. 50 (2013) 344-350; DOI: 10.1002/jhet.1122.
  5. 5. S. M. El-Moghazy, F. F. Barsoum, H. M. Abdel-Rahman and A. A. Marzouk, Synthesis and antiinflammatory activity of some pyrazole derivatives, Med. Chem. Res. 21 (2012) 1722-1733; DOI: 10.1007/s00044-011-9691-4.
  6. 6. M. M. Ghorab, F. A. Ragab, S. I. Alqasoumi, A. M. Alafeefy and S. A. Aboulmagd, Synthesis of some new pyrazolo[3,4-d]pyrimidine derivatives of expected anticancer and radioprotective activity, Eur. J. Med. Chem. 45 (2010) 171-178; DOI: 10.1016/j.bmc.2013.11.042.
  7. 7. B. Parashar, A. Jain, S. Bharadwaj and V. K. Sharma, Synthesis and pharmacological properties of some novel pyrazolidine and pyrazole derivatives, Med. Chem. Res. 21 (2012) 1692-1699; DOI: 10.1007/s00044-011-9687-0.
  8. 8. A. B. Adnan, H. Ariaya, A. Henok and E. A. B. Alaa, Synthesis and biological evaluation of some pyrazole derivatives as anti-malarial agents, Arch. Pharm. Chem. Life Sci. 345 (2012) 147-154; DOI: 10.1002/ardp.201100078.
  9. 9. M. M. Ghorab, H. I. Zienab, A. Mohamad and A. A. Radwan, Synthesis, antimicrobial evaluation and molecular modelling of novel sulfonamides carrying a biologically active quinazoline nucleus, J. Pharm. Res. 36 (2013) 660-670; DOI: 10.1007/s12272-013-0094-6.
  10. 10. M. M. Ghorab, H. I. Zienab, A. A. Radwan and A. Mohamad, Synthesis and pharmacophore modeling of novel quinazolines bearing a biologically active sulfonamide moiety, Acta Pharm. 63 (2013) 1-18; DOI: 10.2478/acph-2013-0006.
  11. 11. M. Lindler, W. Sippl and A. A. Radwan, Pharmacophore elucidation and molecular docking studies on 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid derivatives as COX-2 inhibitors, Sci. Pharm. 78 (2010) 195-214; DOI: 10.3797/scipharm.0912-19.
  12. 12. M. M. Ghorab, F. A. Ragab, H. I. Heiba and M. G. El-Gazzar, Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)- benzenesulfonamide derivatives, Acta Pharm. 61 (2011) 415-425; DOI: 10.2478/v10007-011-0040-4.
  13. 13. M. M. Ghorab, F. A. Ragab, H. I. Hieba, H. A. Yousef and M. G. El-Gazzar, Synthesis of novel pyrazole and pyrimidine derivatives bearing sulfonamide moiety as antitumor and radiosensitizing agents, Med. Chem. Res. 21 (2012) 1376-1383; DOI 10.1007/s00044-013-0721-2.
  14. 14. M. S. Al-Dosari, M. M. Ghorab, M. S. Alsaid, Y. M. Nissan and A. B. Ahmed, Synthesis and anticancer activity of some novel trifluoromethylquinolines carrying a biologically active benzenesulfonamide moiety, Eur. J. Med. Chem. 69 (2013) 373-383; DOI: 10.1016/j.ejmech.2013.08.048.
  15. 15. A. M. Ali, G. E. Saber, N. M. Mahfouz, M. A. El-Gendy, A. A. Radwan and M. A. E. Hamid, Synthesis and three-dimensional qualitative structure selectivity relationship of 3,5-disubstituted-2,4-thiazolidinedion derivatives as COX2 inhibitors, Arch. Pharm. Res. 30 (2007) 1186-1204; DOI: 10.1007/BF02980259.
  16. 16. M. M. Ghorab and M. S. Alsaid, Synthesis and antitumor activity of some novel hydrazide, 1,2-dihydropyridine, chromene, and benzochromene derivatives, J. Heterocyclic Chem. 49 (2012) 272-280; DOI: 10.1002/jhet.829.
  17. 17. M. M. Ghorab, F. A. Ragab, H. I. Hieba and W. M. Ghorab, Design and synthesis of some novel quinoline derivatives as anticancer and radiosensitizing agents targeting VEGFR tyrosine kinase, J. Heterocyclic Chem. 48 (2011) 1269-1279; DOI: /10.1002/jhet.749.
  18. 18. M. M. Ghorab, M. S. Alsaid and E. M. El-Hossary, In vitro cytotoxic evaluation of some new heterocyclic sulfonamide derivatives, J. Heterocyclic Chem. 48 (2011) 563-571; DOI: 10.1002/jhet.619.
  19. 19. M. Alvarado, G. Pilar, M. Macías-González, F. J. Pavón, A. Serrano, N. Jagerovic, J. Elguero, A. Gutiérrez-Rodríguez, S. García-Granda, M. Suardíaz and F. R. de Fonseca, Antiobesity designed multiple ligands: Synthesis of pyrazole fatty acid amides and evaluation as hypophagic agents, Bioorg. Med. Chem. 16 (2008) 10098-10105; DOI: 10.1016/j.bmc.2008.10.023.
  20. 20. I. L. Finar and R. J. Hurlock, The skraup reaction with aminopyrazoles, J. Chem. Soc. 1958, 3259-3263; DOI: 10.1039/JR9580003259.
  21. 21. H. Naeimi, Z. S. Nazifi, S. M. Amininezhad and M. Amouheidari, Synthesis, characterization and in vitro antimicrobial activity of some new Schiff bases and their complexes, J. Antibiot. 66 (2013) 687-689; DOI: 10.1038/ja.2013.73.
DOI: https://doi.org/10.2478/acph-2014-0028 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 335 - 344
Accepted on: May 15, 2014
Published on: Oct 8, 2014
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
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© 2014 Awwad A. Radwan, Mostafa M. Ghorab, Mansour S. Alsaid, Fares K. Alanazi, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.