Skip to main content
Have a personal or library account? Click to login
Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters Cover

Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters

Open Access
|Jun 2014

References

  1. 1. N. J. Abbott, Blood-brain barrier structure and function and the challenges for CNS drug delivery, J. Inherit. Metab. Dis. 36 (2013) 437-449; DOI: 10.1007/s10545-013-9608-0.
  2. 2. L. A. Khawli and S. Prabhu, Drug delivery across the blood-brain barrier, Mol. Pharm. 10 (2013) 1471-1472; DOI: 10.1021/mp400170b.
  3. 3. A. H. Schinkel, J. J. Smith, O. van Tellingen, J. H. Beijnen, E. Wagenaar, L. van Deemter, C. A. Mol, M. A. van der Valk, E. C. Robanus-Maandag and H. P. te Riele, Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs, Cell 77 (1994) 491-502; DOI: 10.1016/0092-8674(94)90212-7.
  4. 4. D. S. Miller, Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier, Trends Pharmacol. Sci. 31 (2010) 246-254; DOI: 10.1016/j.tips.2010.03.003.
  5. 5. J. Malmo, A. Sandvig, M. K. Varum and S. P. Strand, Nanoparticle mediated P-glikoprotein silencing for improved drug delivery across the blood-brain barrier: a siRNA-chitosan approach, PLoS ONE 8 (2013) e54182; DOI: 10.1371/journal.pone.0054182.
  6. 6. F. J. Sharom, ABC multidrug transporters: structure, function and role in chemoresistance, Pharmacogenomics 9 (2008) 105-127; DOI: 10.2217/14622416.9.1.105.
  7. 7. C. J. Bachmeier, W. J. Trickler and D. W. Miller, Comparison of drug efflux transport kinetics in various blood-brain barrier models, Drug Metab. Dispos. 34 (2006) 998-1003; DOI: 10.1124/dmd. 105.006999.
  8. 8. S. P. C. Cole, Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future, Annu. Rev. Pharmacol. Toxicol. 54 (2014) 95-117; DOI: 10.1146/annurev-pharmtox-011613-135959.
  9. 9. S. A. Kliewer, The nuclear pregnane X receptor regulates xenobiotic detoxification, J. Nutr. 133 (2003) 2444S-2447S.
  10. 10. B. I. Sikic, Modulation of multidrug resistance: at the threshold, J. Clin. Oncol. 11 (1993) 1629-1635.
  11. 11. T. Eichhorn and T. Efferth, P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs, J. Ethnopharmacol. 141 (2012) 557-570; DOI: 10.1016/j.jep.2011.08.053.
  12. 12. O. Khantamat, W. Chaiwangyen and P. Limtrakul, Screening of flavonoids for their potential inhibitory effect on p-glycoprotein activity in human cervical carcinoma kb cells, Chiang Mai Med. Bull. 43 (2004) 45-56.
  13. 13. S. Zhou, L. Y. Lim and B. Chowbay, Herbal modulation of P-glycoprotein, Drug Metab. Rev. 36 (2004) 57-104.
  14. 14. P. Limtrakul, O. Khantamat and K. Pintha, Inhibition of P-glycoprotein function and expression by kaempferol and quercetin, J. Chemother. 17 (2005) 86-95; DOI: 10.1179/joc.2005.17.1.86.
  15. 15. European Pharmacopoeia, 6th ed., Vol. 2, Council of Europe, Strassbourg Cedex 2008.
  16. 16. T. Sugamo, K. Nakamura and H. Tamura, Effects of cytochrome P450 inducers on the gene expression of ocular xenobiotic metabolizing enzymes in rats, J. Health Sci. 55 (2009) 923-929; DOI: 10.1248/jhs.55.923.
  17. 17. U. Andersson, K. Grankvist, A. T. Bergenheim, P. Behnam-Motlagh, H. Hedman and R. Henriksson, Rapid induction of long-lasting drug efflux activity in brain vascular endothelial cells but not malignant glioma following irradiation, Med. Oncol. 19 (2002) 1-9.
  18. 18. R. Zhang, J. Jie, Y. Zhou, Z. Cao and W. Li, Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo, Am. J. Chin. Med. 37 (2009) 657-667; DOI: 10.1142/S0192415X09007144.
  19. 19. J. Zhang, F. Zhou, X. Wu, Y. Gu, H. Ai, Y. Zheng, Y. Li, X. Zhang, G. Hao, J. Sun, Y. Peng and G. Wang, 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions, Drug Metab. Dispos. 38 (2010) 2179-2187; DOI: 10.1124/dmd. 110.034793.
  20. 20. A. Kawase, A. Yamada, Y. Gamou, Ch. Tahara, F. Takeshita, K. Murata, H. Matsuda, K. Samukawa and M. Iwaki, Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism, J. Nat. Med. (2013); DOI 10.1007/s11418-013-0791-y.
  21. 21. M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, Br. J. Clin. Pharmacol. 53 (2002) 75-82; DOI: 10.1046/j.0306-5251.2001.01516.x.
  22. 22. C. C. Weber, S. Kressmann, G. Fricker and W. E. Muller, Modulation of P-glycoprotein function by St John’s wort extract and its major constituents, Pharmacopsychiatry 37 (2004) 292-298; DOI: 10.1055/s-2004-832686.
  23. 23. Ch. Garrovo, A. Rosati, F. Bartoli and G. Decorti, St John’s wort modulation and developmental expression of multidrug transporters in the rat, Phytother. Res. 20 (2006) 468-473; DOI: 10.1002/ ptr.1880.
  24. 24. L. Li, J. D. Stanton, A. H. Tolson, Y. Luo and H. Wang, Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways, Pharm. Res. 26 (2009) 872-882; DOI: 10.1007/s11095-008-9788-8.
  25. 25. G. Scambia, F. O. Ranelletti, P. B. Panici, R. De Vincenzo, G. Bonanno, G. Ferrandina, M. Piantelli, S. Bussa, C. Rumi, M. Cianfriglia and S. Mancuso, Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target, Cancer Chemoth. Pharm. 34 (1994) 459-464; DOI: 10.1371/journal.pone.0051764.
  26. 26. A. B. Shapiro and V. Ling, Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein, Biochem. Pharmacol. 53 (1997) 587-596; DOI: 10.1016/S0006-2952(96) 00826-X.
  27. 27. M. E. Morris and S. Zhang, Flavonoid-drug interactions: Effects of flavonoids on ABC transporters, Life Sci. 78 (2006) 2116-2130; DOI: 10.1016/j.lfs. 2005.12.003.
DOI: https://doi.org/10.2478/acph-2014-0020 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 223 - 232
Accepted on: Feb 27, 2014
Published on: Jun 6, 2014
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Related subjects:

© 2014 Przemyslaw M. Mrozikiewicz, Anna Bogacz, Joanna Bartkowiak-Wieczorek, Radoslaw Kujawski, Przemyslaw L. Mikolajczak, Marcin Ozarowski, Boguslaw Czerny, Beata Mrozikiewicz-Rakowska, Edmund Grzeskowiak, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.