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Investigation of in situ gelling alginate formulations as a sustained release vehicle for co-precipitates of dextromethrophan and Eudragit S 100 Cover

Investigation of in situ gelling alginate formulations as a sustained release vehicle for co-precipitates of dextromethrophan and Eudragit S 100

Acta Pharmaceutica
Volume 64 (2014): Issue 1 (March 2014)
By: Gamal Mohamed El Maghraby,  Ehab Mostafa Elzayat and  Fars Kaed Alanazi  
Open Access
|Mar 2014

References

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    Search in Google Scholar
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    Search in Google Scholar
  32. 32. S. Miyazaki, W. Kubo and D. Attwood, Oral sustained delivery of theophylline using in situ gelation of sodium alginate, J. Control Release 67 (2000) 275-280; DOI: 10.1016/s0168-3659(00)00214-5.10.1016/S0168-3659(00)00214-5
    Search in Google Scholar
  33. 33. S. Miyazaki, N. Kawasaki, W. Kubo, K. Endo and D. Attwood, Comparison of in situ gelling formulations for the oral delivery of cimetidine, Int. J. Pharm. 220 (2001) 161-168; DOI: 10.1016/ S0378-5173(01)00669-X.10.1016/S0378-5173(01)00669-X
    Search in Google Scholar
  34. 34. W. Kubo, S. Miyazaki and D. Attwood, Oral sustained delivery of paracetamol from in situ- -gelling gellan and sodium alginate formulations, Int. J. Pharm. 258 (2003) 55-64; DOI: 10.1016/ S0378-5173(03)00163-7.10.1016/S0378-5173(03)00163-7
    Search in Google Scholar
  35. 35. D. Schmaljohann, Thermo- and pH-responsive polymers in drug delivery, Adv. Drug Deliv. Rev. 58 (2006) 1655-1670; DOI: 10.1016/j.addr.2006.09.020.10.1016/j.addr.2006.09.020
    Search in Google Scholar
  36. 36. T. Coviello, P. Matricardi, C. Marianecci and F. Alhaique, Polysaccharide hydrogels for modified release formulations, J. Control. Release 119 (2007) 5-24; DOI: S0168-3659(07)00039-9 [pii] 10.1016/j.jconrel.2007.01.004.
    Search in Google Scholar
  37. 37. G. Rohith, B. K. Sridhar and A. Srinatha, Floating drug delivery of a locally acting H2-antagonist: an approach using an in situ gelling liquid formulation, Acta Pharm. 59 (2009) 345-354; DOI: 10.2478/v10007-009-0021-z.10.2478/v10007-009-0021-z
    Search in Google Scholar
  38. 38. L. Rodriguez, O. Caputo, M. Cini, C. Cavallari and R. Grecchi, In vitro release of theophylline from directly-compressed matrices containing methacrylic acid copolymers and/or dicalcium phosphate dehydrate, Farmaco 48 (1993) 1597-1604.
    Search in Google Scholar
  39. 39. L. S. da Fonseca, R. P. Silveira, A.M. Deboni, E. V. Benvenutti, T. M. Costa, S. S. Guterres and A.
    Search in Google Scholar
  40. R. Pohlmann, Nanocapsule@xerogel microparticles containing sodium diclofenac: a new strategy to control the release of drugs, Int. J. Pharm. 358 (2008) 292-295; DOI: S0378-5173(08) 00118-X [pii] 10.1016/j.ijpharm.2008.02.005.
    Search in Google Scholar
  41. 40. E. F. Reynolds James, Dextromethorphan Hydrobromide, Royal Pharmaceutical Society, London, 1996, p. 1066.
    Search in Google Scholar
  42. 41. J. L. Bem and R. Peck, Dextromethorphan. An overview of safety issues, Drug Safety 7 (1992) 190-199.10.2165/00002018-199207030-00004
    Search in Google Scholar
  43. 42. E. S. Pender and B. R. Parks, Toxicity with dextromethorphan-containing preparations: a literature review and report of two additional cases, Pediatr. Emerg. Care 7 (1991) 163-165.
    Search in Google Scholar
  44. 43. G. M. El Maghraby, Synergistic enhancement of itraconazole dissolution by ternary system formation with pluronic F68 and hydroxypropylmethylcellulose, Sci. Pharm. 77 (2009) 401-417; DOI: 10.3797/scipharm.0901-08. 10.3797/scipharm.0901-08
    Search in Google Scholar
  45. 44. F. K. Alanazi, M. El-Badry and I. A. Alsarra, Spray-dried HPMC microparticles of indomethacin impact of drug-polymer ratio and viscosity of the Polymeric solution on dissolution, Saudi Pharm. J. 14 (2006) 100-107.
    Search in Google Scholar
  46. 45. G. M. El Maghraby, E. M. Elzayat and F. K. Alanazi, Development of modified in situ gelling oral liquid sustained release formulation of dextromethorphan, Drug Dev. Ind. Pharm. (2011); DOI: 10.3109/03639045.2011.634811.10.3109/03639045.2011.634811
    Search in Google Scholar
  47. 46. P. S. Rajinikanth and B. Mishra, Floating in situ gelling system of acetohydroxamic acid for clearance of H. pylori, Drug Dev. Ind. Pharm. 34 (2008) 577-587; DOI: 10.1080/03639040701831819.10.1080/03639040701831819
    Search in Google Scholar
  48. 47. K. A. Khan, The concept of dissolution efficiency, J. Pharm. Pharmacol. 27 (1975) 48-49.10.1111/j.2042-7158.1975.tb09378.x
    Search in Google Scholar
  49. 48. M. R. Louhaichi, S. Jebali, M. H. Loueslati, N. Adhoum and L. Monser, Simultaneous determination of pseudoephedrine, pheniramine, guaifenesin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography, Talanta 78 (2009) 991-997; DOI: 10.1016/j.talanta.2009.01.019.10.1016/j.talanta.2009.01.019
    Search in Google Scholar
  50. 49. F. Alanazi, H. Li, D. S. Halpern, S. Oie and D. R. Lu, Synthesis, preformulation and liposomal formulation of cholesteryl carborane esters with various fatty chains, Int. J. Pharm. 255 (2003) 189-197; DOI: S0378517303000887.10.1016/S0378-5173(03)00088-7
    Search in Google Scholar
  51. 50. M. Malladi, R. Jukanti, R. Nair, S. Wagh, H. S. Padakanti and A. Mateti, Design and evaluation of taste masked dextromethorphan hydrobromide oral disintegrating tablets, Acta Pharm. 60 (2010) 267-280; DOI: 10.2478/v10007-010-0025-8.10.2478/v10007-010-0025-8
    Search in Google Scholar
  52. 51. R. P. Raffin, D. Jornada, S. Haas, A. R. Pohlmann and S. S. Guterres, Pantoprazole sodiumloaded controlled release microparticles, in 15th International Symposium on Microencapsulation, Parma, ed. (Italy, 2005), pp. 7-8.
    Search in Google Scholar
  53. 52. K. H. Kim, M. J. Frank and N. L. Henderson, Application of differential scanning calorimetry to the study of solid drug dispersions, J. Pharm. Sci. 74 (1985) 283-289.10.1002/jps.2600740312
    Search in Google Scholar
  54. 53. R. J. Fessenden and J. S. Fessenden, Fessenden and Fessenden Organic Chemistry, Brooks/Cole publishing company, Pacific Grove, 1990, pp. 323-390.
    Search in Google Scholar
  55. 54. Technical Information on EUDRAGIT L 100 and EUDRAGIT S 100, http://eudragit.evonik.com/product/eudragit/Documents/evonik-specification-eudragit-l-100-and-s-100.pdf; access date January 10, 2011.
    Search in Google Scholar
  56. 55. M. R. Jenquin and J. W. McGinity, Characterization of acrylic resin matrix films and mechanisms of drug-polymer interaction, Int. J. Pharm. 101 (1994) 23-24.10.1016/0378-5173(94)90072-8
    Search in Google Scholar
  57. 56. K. O. R. Lehman, Chemistry and application properties of polymethacrylate coating systems, Informa Healthcare USA, Inc., New York, 1990, pp. 101-174.
    Search in Google Scholar
  58. 57. B. J. Lee, J. H. Cui, T. W. Kim, M. Y. Heo and C. K. Kim, Biphasic release characteristics of dual drug-loaded alginate beads, Arch Pharm. Res. 21 (1998) 645-650.10.1007/BF029767519868531
    Search in Google Scholar
  59. 58. T. Higuchi, Rate of release of medicaments from ointment bases containing drugs in suspension, J. Pharm. Sci. 50 (1961) 874-875. 10.1002/jps.260050101813907269
    Search in Google Scholar
DOI: https://doi.org/10.2478/acph-2014-0002 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 29 - 44
Published on: Mar 25, 2014
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
dextromethorphan,
solid dispersion,
in situ gelling,
alginate gels
Related subjects:
Pharmacy,
Pharmacy, other

© 2014 Gamal Mohamed El Maghraby, Ehab Mostafa Elzayat, Fars Kaed Alanazi, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

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