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Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil Cover

Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil

Open Access
|Dec 2013

Abstract

Prevention of skin aging and its treatment is an emerging field for development of new formulations in cosmetics. Accordingly, plant extracts with antioxidant properties are beneficial cosmetic ingredients for this purpose. This study was aimed at developing a stable and easily manufactured emulgel including green tea extract and rose oil that is effective on the barrier function and hydration of the skin. An emulgel formulation containing 20 % green tea extract and 5 % rose oil was designed as a result of pre-formulation studies. Physicochemical characterization, in vitro stability studies, in vivo water content of the stratum corneum and transepidermal water loss studies were carried out afterwards. In vivo studies on ten female subjects were evaluated by using non-invasive skin bioengineering techniques. Finally, a cosmetically acceptable, stable and effective emulgel formulation for skin barrier function with good hydrating properties was obtained for skin hydration, protection and anti-aging purposes.

DOI: https://doi.org/10.2478/acph-2013-0037 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 531 - 544
Published on: Dec 31, 2013
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Related subjects:

© 2013 Evren Algin Yapar, Özge Ýnal, M. Sedef Erdal, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.