Fig. 1

Analyses of blood plasma proteins done in December 2019 and March 2023_ Parameters that were out of the reference range are highlighted_ Values marked as dash mean no data available_
| December 2019 | March 2023 | ||||
|---|---|---|---|---|---|
| Fraction | % | Reference range % | g/l | g/l | Reference range |
| Albumin | 62.9 | 60.3 – 72.8 | 44.0 | 41.4 | 37.5 – 50.1 |
| Alpha1-globulins | 2.2 | 1.0 – 2.6 | 1.5 | 3.0 | 1.9 – 4.6 |
| Alpha2-globulins | 8.6 | 7.2 – 11.8 | 6.0 | 6.1 | 4.8 – 10.5 |
| Beta1-globulins | 6.0 | 5.6 – 9.1 | 4.2 | - | - |
| Beta2-globulins | 3.3 | 2.2 – 5.7 | 2.3 | - | - |
| Beta-globulins | - | - | - | 6.8 | 4.8 – 11.0 |
| Gamma-globulins | 17.0> | 6.2 – 15.4 | 11.9 | 11.7 | 6.2 – 15.1 |
| Albumin/Globulin ratio | 1.70 | 1.2 – 2.0 | - | 1.5 | 1.2 – 2.0 |
| Monoclonal IgG kappa | 0.9 | - | 0.6 | - | - |
| Total protein | 69.9 | 62 – 81 | - | 67 | 62 – 81 |
Blood analyses before taking Synthesit in February 2020, during taking in July 2021, and after taking it in March 2023_ Parameters that were out of the reference range are highlighted_ Values marked as dash mean no data available_
| Parameter | Before taking Synthesit 02/2020 | During taking Synthesit 7/2021 | After taking Synthesit 03/2023 | Reference range | Unit of measurement |
|---|---|---|---|---|---|
| Haematocrit | 40.9 | - | 42.7 | 35.0 – 47.0 | % |
| Haemoglobin | 14.0 | 14.8 | 14.5 | 11.7 – 16.0 | g/dl |
| Erythrocytes | 4.58 | 4.90 | 4.72 | 3.80 – 5.30 | *106/μl |
| Thrombocytes | 116 | 260 | 123 | 150 – 400 | *103/μl |
| Leukocytes | 7.07 | 4.20 | 6.80 | 4.50 – 11 | *103/μl |
| Neutrophils (total), % | 40.30 | 66 | 48.40 | 48.0 – 78.0 | % |
| Lymphocytes, % | 50.5 | - | 44.1 | 19.0 – 37.0 | % |
| Monocytes, % | 7.5 | - | 5.6 | 3.0 – 11.0 | % |
| Eosinophils, % | 1.4 | 3 | 1.6 | 1.0 – 5.0 | % |
| Basophils, % | 0.3 | - | 0.3 | <1.0 | % |
| Neutrophils abs. | 2.85 | - | 3.29 | 1.56 – 6.13 | *103/μl |
| Lymphocytes abs. | 3.57 | - | 3.00 | 1.18 – 3.74 | *103/μl |
| Monocytes abs. | 0.53 | 1 | 0.38 | 0.20 – 0.95 | *103/μl |
| Eosinophils abs. | 0.10 | - | 0.11 | 0.00 – 0.70 | *103/μl |
| Basophils abs. | 0.02 | - | 0.02 | 0.00 – 0.20 | *103/μl |
| Erythrocyte Sedimentation Rate (ESR) | 12 | 4 | 7 | <30 | mm/h |