Fig. 1
Fig. 2
Fig. 3
Enhanced susceptibility of NTM to aminoglycosides through gene deletion (39)
| Deletion of gene | Increased susceptibility to antibiotic |
|---|---|
| AAC(2 ′ ) | kanamycin B, tobramycin, dibekacin, and gentamicin C |
| Eis2 | capreomycin, hygromycin B, amikacin, and kanamycin |
| Eis1 | no affect on drug susceptibility |
An overview of the increase in NTM cases in United States (7)
| Year duration | Increase in cases per 100 people |
|---|---|
| from the early 1980s to 2013 | from 2.4 to 15.2 |
| 1997–2007 among the elderly population (>65 years) | from 20 to 47 |
| 1995–2006 | from 0.9 to 2.9 |