Skip to main content
Have a personal or library account? Click to login
Pathophysiology of Airway Afferent Nerves Cover

Pathophysiology of Airway Afferent Nerves

By:  and    
Open Access
|May 2022
Read online

References

  1. 1. Korpáš J, Tomori Z. Cough and other respiratory reflexes. In: Herzog H, editor. Basel: Karger, 1979; 1-356.
  2. 2. Mazzone SB, Undem BJ. Vagal Afferent Innervation of the Airways in Health and Disease. Physiol Rev.2016; 96(3): 975-1024.10.1152/physrev.00039.2015
  3. 3. Undem BJ, Chuaychoo B, Lee MG, Weinreich D, Myers AC, Kollarik M. Subtypes of vagal affe rent C fibers in guinea pig lungs. J Physiol 2004; 556: 905–917.10.1113/jphysiol.2003.060079
  4. 4. Ho CY, Gu Q, Lin YS, Lee LY. Sensitivity of vagal afferent endings to chemical irritants in the rat lung. Respir Physiol 2001; 127: 113–124.10.1016/S0034-5687(01)00241-9
  5. 5. Canning BJ, Mazzone SB, Meeker SN, Mori N, Reynolds SM, Undem BJ. Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs. J Physiol 2004; 557: 543–558.10.1113/jphysiol.2003.057885
  6. 6. West PW, Canning BJ, Merlo-Pich E, Woodcock AA, Smith JA. Morphologic characterization of nerves in whole-mount airway biopsies. Am J Respir Crit Care Med 2015; 192: 30–39.10.1164/rccm.201412-2293OC
  7. 7. Kollarik M, Undem BJ. Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig. J Physiol 2002; 543: 591–600.10.1113/jphysiol.2002.022848
  8. 8. Liu J, Yu J. Spectrum of myelinated pulmonary afferents (II). Am J Physiol Regul Integr Comp Physiol 2013; 305: R1059–R1064.10.1152/ajpregu.00125.2013
  9. 9. Kaufman MP, Iwamoto GA, Ashton JH, Cassidy SS. Responses to inflation of vagal afferents with endings in the lung of dogs. Circ Res 1982; 51: 525–531.10.1161/01.RES.51.4.525
  10. 10. Lin YJ, Lin RL, Ruan T, Khosravi M, Lee LY. A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents. J Appl Physiol 2015; 118: 273–281.10.1152/japplphysiol.00805.2014
  11. 11. Wang AL, Blackford TL, Lee LY. Vagal bronchopulmonary C-fibers and acute ventilatory response to inhaled irritants. Respir Physiol 1996; 104: 231–239.10.1016/0034-5687(96)00014-X
  12. 12. McGovern AE, Short KR, Moe AAK, Mazzone SB. Translational review: Neuroimmune mechanisms in cough and emerging therapeutic targets. Journal of Allergy and Clinical Immunology 2018; 142 (5): 1392-1402.10.1016/j.jaci.2018.09.004
  13. 13. Pack AI, DeLaney RG. Response of pulmonary rapidly adapting receptors during lung inflation. J Appl Physiol 1983; 55: 955–963.10.1152/jappl.1983.55.3.955
  14. 14. Kollarik M, Dinh QT, Fischer A, Undem BJ. Capsaicin-sensitive and insensitive vagal bronchopulmonary C-fibres in the mouse. J Physiol 2003; 551: 869–879.10.1113/jphysiol.2003.042028
  15. 15. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 1998; 21: 531–543.10.1016/S0896-6273(00)80564-4
  16. 16. Ni D, Gu Q, Hu HZ, Gao N, Zhu MX, Lee LY. Thermal sensitivity of isolated vagal pulmonary sensory neurons: role of transient receptor potential vanilloid receptors. Am J Physiol Regul Integr Comp Physiol 2006; 291: R541–R550.10.1152/ajpregu.00016.2006
  17. 17. Voets T, Droogmans G, Wissenbach U, Janssens A, Flockerzi V, Nilius B. The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature 2004; 430: 748–754.10.1038/nature02732
  18. 18. Pecova R, Frlickova Z, Pec J, Tatar M. Cough sensitivity in atopic dermatitis. Pulm Pharmacol Ther 2003, 16(4): 203-206.10.1016/S1094-5539(02)00214-6
  19. 19. Pecova R, Vrlik M, Tatar M. Cough sensitivity in allergic rhinitis. J Physiol Pharmacol. 2005; 56 (Suppl. 4): 171-178.
  20. 20. Pecova R, Zucha J, Pec M, Neuschlova M, Hanzel P, Tatar M. Cough reflex sensitivity testing in seasonal allergic rhinitis patients and healthy volunteers. J Physiol Pharmacol. 2008; 59 (Suppl 6): 557-64.
  21. 21. Undem BJ, Potenzieri C. Autonomic neural control of intrathoracic airways. Comp Physiol 2012; 2: 1241–1267.
  22. 22. Grandordy BM, Thomas V, de Lauture D, Marsac J. Cumulative dose-response curves for assessing combined effects of salbutamol and ipratropium bromide in chronic asthma. Eur Respir J 1988; 1: 531–535.10.1183/09031936.93.01060531
  23. 23. Gross NJ, Skorodin MS. Anticholinergic, antimuscarinic bronchodilators. Am Rev Respir Dis 1984; 129: 856–870.10.1164/arrd.1984.129.5.8566372560
  24. 24. McAlexander MA, Gavett SH, Kollarik M, Undem BJ. Vagotomy reverses established allergen-induced airway hyperreactivity to methacholine in the mouse. Respir Physiol Neurobiol 2015; 212–214: 20–24.10.1016/j.resp.2015.03.007482716225842220
  25. 25. Handforth A, DeGiorgio CM, Schachter SC, Uthman BM, Naritoku DK, Tecoma ES, Henry TR, Collins SD, Vaughn BV, Gilmartin RC, Labar DR, Morris GL 3rd, Salinsky MC, Osorio I, Ristanovic RK, Labiner DM, Jones JC, Murphy JV, Ney GC, Wheless JW. Vagus nerve stimulation therapy for partial-onset seizures: a randomized active-control trial. Neurology 1998; 51: 48–55.10.1212/WNL.51.1.489674777
  26. 26. Taguchi O, Kikuchi Y, Hida W, Iwase N, Okabe S, Chonan T, Takishima T. Prostaglandin E2 inhalation increases the sensation of dyspnea during exercise. Am Rev Respir Dis 1992; 145: 1346–1349.10.1164/ajrccm/145.6.13461596001
  27. 27. Tetzlaff K, Leplow B, ten Thoren C, Dahme B. Perception of dyspnea during histamine- and methacholine-induced bronchoconstriction. Respiration 1999; 66: 427–433.10.1159/00002942610516539
  28. 28. Hilton E, Marsden P, Thurston A, Kennedy S, Decalmer S, Smith JA. Clinical features of the urge-to-cough in patients with chronic cough. Respir Med 2015; 109: 701–707.10.1016/j.rmed.2015.03.01125892291
  29. 29. Dicpinigaitis PV, Bhat R, Rhoton WA, Tibb AS, Negassa A. Effect of viral upper respiratory tract infection on the urge-to-cough sensation. Respir Med 2011; 105: 615–618.10.1016/j.rmed.2010.12.00221185164
  30. 30. Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Domingo Ribas C, Hilton Boon M, Kantar A, Lai K, McGarvey L, Rigau D, Satia I, Smith J, Song WJ, Tonia T, van den Berg JWK, van Manen MJG, Zacharasiewicz A. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020; 55(1).10.1183/13993003.01136-2019694254331515408
  31. 31. Mazzone SB, McGarvey L. Mechanisms and Rationale for Targeted Therapies in Refractory and Unexplained Chronic Cough. Clin Pharmacol Ther. 2021; 109(3): 619–636.10.1002/cpt.2003798394132748976
DOI: https://doi.org/10.2478/acm-2022-0001 | Journal eISSN: 1338-4139 (formerly 1335-8421) | Journal ISSN: 1335-8421
Language: English
Page range: 1 - 7
Submitted on: Feb 1, 2022
Accepted on: Feb 21, 2022
Published online: May 9, 2022
Published in print: Apr 1, 2022
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 3 issues per year

© 2022 Jakusova Janka, Pecova Renata, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.