Figure 1.
Figure 2.
Univariate analysis of recurrence
| Variables | No recurrence (N = 25) | Recurrence (N = 13) | P-value |
|---|---|---|---|
| Age (years) | |||
| <50 | 10 | 6 | 0.981 |
| >50 | 15 | 7 | |
| Tumor grading | |||
| Grade 1 | 14 | 1 | 0.008 |
| Grade 2 and 3 | 11 | 12 | |
| Surgical margins | |||
| R0/R1 | 25 | 11 | 0.222 |
| R2 | 0 | 2 | |
| Tumor size (cm) | |||
| <15 | 9 | 5 | 1 |
| >15 | 16 | 8 | |
| Preoperative RT | |||
| Yes | 17 | 4 | 0.064 |
| No | 8 | 9 | |
| Adjuvant chemotherapy | |||
| Yes | 1 | 7 | 0.002 |
| No | 24 | 6 | |
| Postoperative RT | |||
| Yes | 9 | 7 | 0.476 |
| No | 16 | 6 | |
| >1 visceral organ resection | |||
| Yes | 20 | 12 | 0.643 |
| No | 5 | 1 | |
| Histologic subtype of liposarcoma | |||
| Well differentiated, myxoid | 6 | 0 | 0.046 |
| Dedifferentiated, pleomorphic, mixed type | 7 | 9 | |
Sarcoma histology, surgical margins, and tumor grading
| Histologic diagnosis | No (%) | |
|---|---|---|
| Liposarcoma | ||
| Well differentiated | 5 | (58) |
| Dedifferentiated | 9 | |
| Myxoid | 1 | |
| Pleomorphic | 1 | |
| Mixed type | 6 | |
| Leiomyosarcoma | 4 (11) | |
| Malignant peripheral nerve sheath tumor | 1 (3) | |
| Malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma) | 1 (3) | |
| Mixofibrosarcoma | 1 (3) | |
| Rhabdomyosarcoma | 1 (3) | |
| Spindle cell sarcoma | 8 (21) | |
| Surgical margins | ||
| R0 | 23 (61) | |
| R1 | 13 (34) | |
| R2 | 2 (5) | |
| Tumor grading | ||
| Grade 1 | 15 (40) | |
| Grade 2 | 7 (18) | |
| Grade 3 | 16 (42) | |
Number of organs resected in 33 patients (87%)
| Organs | No (%) |
|---|---|
| Kidney | 22 (58) |
| Colon | 18 (43) |
| Uterus and both fallopian tubes | 8 (21) |
| Adrenal gland | 4 (11) |
| Spleen | 4 (11) |
| Distal pancreas | 3 (8) |
| Inferior vena cava | 2 (5) |
| Diaphragm (partial) | 2 (5) |
| Wedge resection of duodenum | 1 (3) |
| Segmental resection of ureter with end-to-end anastomosis | 1 (3) |
| Paraaortic lymphnodes | 1 (3) |
| Left uterine tube | 1 (3) |
Multivariate analysis of recurrence
| Step | Variable | Adjusted OR (95% CI) | P-value |
|---|---|---|---|
| 1 | Preoperative RT | 0.21 (0.25–0.89) | 0.011 |
Patient characteristics and demographic data
| Study period | June 2003–December 2019 |
| Number of patients (n) | 38 |
| Male (n) | 11 (29%) |
| Female (n) | 27 (71%) |
| Age (years) | 26–80 (median 54) |
| Duration of symptoms (months) | 1–24 (median 4) |
| Tumor size (cm) | 3–48 (median 22) |
| Presentations (some patients had >1 presentation) | No (%) |
| Abdominal mass | 34 (90) |
| Abdominal pain, discomfort | 8 (21) |
| Anorexia | 1 (3) |
| Incidental finding during appendectomy | 1 (3) |
| Incidental finding during gynecologic procedures | 2 (5) |
| Asymptomatic | 1 (3) |
| Preoperative core needle biopsy | 20 (53) |
| Previous operation with biopsy | 7 (18) |
| Preoperative RT | 21 (55) |
| Postoperative RT | 16 (42) |
| Location of tumors | |
| Right | 17 (45) |
| Left | 13 (34) |
| Pelvis | 8 (21) |
Postoperative complications
| Complications | No of pt. | Management |
|---|---|---|
| Intraabdominal bleeding | 3 | Reoperation with bleeding control |
| Wound dehiscence | 1 | Reoperation with re-suturing abdominal wound |
| Prolonged ileus | 1 | Conservative treatment |