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Disseminated gonococcal infection during two decades in the university hospital, Thailand Cover

Disseminated gonococcal infection during two decades in the university hospital, Thailand

Open Access
|Jun 2024

Figures & Tables

Figure 1.

Flow chart of the recruitment of DGI patients. DGI, disseminated gonococcal infection.
Flow chart of the recruitment of DGI patients. DGI, disseminated gonococcal infection.

The pattern of joint involvements

Number (%)
Number of joint involvements
  Monoarthritis14 (36.8)
  Oligoarthritis20 (52.6)
  Polyarthritis4 (10.5)
Site of joint involvements
  Wrist joint18 (47.4)
  Ankle joint17 (44.7)
  Knee joint14 (36.8)
  Shoulder joint6 (15.8)
  Metacarpophalangeal (MCP) joint6 (15.8)
  Elbow joint5 (13.2)
  Proximal interphalangeal (PIP) joint3 (7.9)
  Hip joint2 (5.3)
  Tarsometatarsal joint2 (5.3)
  Sternoclavicular joint1 (2.6)
  Axial and sacroiliac joint0 (0)
  Temporomandibular joint0 (0)

Clinical data of the patients with DGI

Total patients (n = 41)Definite DGI (n = 27)Probable DGI (n = 14)P*
Presenting symptoms
  Fever37 (90.2%)26 (96.3%)11 (78.6%)0.107
  Chills14 (34.1%)8 (29.6%)6 (42.9%)0.494
  Joint pain41 (100%)27 (100%)14 (100%)
  Skin lesions11 (26.8%)7 (25.9%)4 (28.6%)1.000
Genitourinary symptoms (dysuria or discharge)12 (29.3%)9 (33.3%)3 (21.4%)0.494
Presenting signs
Arthritis38 (92.7%)25 (92.6%)13 (92.9%)1.000
  Number
  Median, IQR, range2, 1–3, 1–142, 1–3, 1–142, 1–3, 1–71.000
Distribution of joint involvement 0.885
  Monoarthritis14 (36.8%)10 (40%)4 (30.8%)
  Oligoarthritis20 (52.6%)12 (48%)8 (61.5%)
  Polyarthritis4 (10.5%)3 (12%)1 (7.7%)
Tenosynovitis26 (63.4%)14 (51.9%)12 (85.7%)0.033
Skin lesion16 (39%)9 (33.3%)7 (50%)0.300
Urethral discharge
  Yes7 (17.1%)5 (20.8%)2 (14.3%)
  No31 (75.6%)19 (79.2%)12 (85.7%)1.000
  Missing3 cases3 cases-

Demographic data of patients with DGI

Total patients (n = 41)Definite DGI (n = 27)Probable DGI (n = 14)
Age at diagnosis30, 20–37, 16–8133, 22–41, 16–8122, 19–32, 16–42
Median, IQR, range (years)
  15–3022 (53.7%)12 (44.4%)10 (71.4%)
  31–4010 (24.4%)8 (29.6%)2 (14.3%)
  41–505 (12.2%)3 (11.1%)2 (14.3%)
  51–601 (2.4%)1 (3.7%)0
  >603 (7.3%)3 (11.1%)0
Sex
  Male17 (41.5%)10 (37%)7 (50%)
  Female24 (58.5%)17 (63%)7 (50%)

Microbiological data of the patients with DGI

Number of tested patients (%)Number of positive specimens (%)
Hemoculture32 (78.0)4 (12.5)
Synovial fluid for aerobic culture33 (80.5)10 (30.3)
Synovial fluid for Gram stain29 (70.7)11 (37.9)
Synovial fluid for PCR or 16s-rRNA amplification for N. gonorrhoeae3 (7.3)3 (100)
Specimen from mucosae for aerobic culture
  Cervical swab15 (36.5)5 (33.3)
  Urethral swab16 (39.0)3 (18.8)
  Pharyngeal swab15 (36.5)2 (13.3)
  Rectal swab11 (26.8)1 (9.1)
Pustule for aerobic culture1 (2.4)1 (100)
DOI: https://doi.org/10.2478/abm-2024-0018 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 125 - 132
Published on: Jun 28, 2024
Published by: Chulalongkorn University
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2024 Kanphai Wongjarit, Sittichai Ukritchon, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution 4.0 License.