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The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study Cover

The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study

Open Access
|Oct 2023

Figures & Tables

The association between sex, smoking and mean MPOD_

Parameters (n = 62)Mean MPOD (d.u.)

<0.5 (d.u.)≥0.5 (d.u.)X2P
Male13140.860.35
Female2114
Smoking
  Yes24210.160.70
  No107

Multivariate analysis with mean MPOD by logistic regression_

Model 1MPOD (d.u.)ORStd. ErrzP>|z|95% CIModel 2MPOD (d.u.)ORStd. ErrzP>|z|95% CI
hsCRP >3(mg/L)0.340.25−1.450.150.08–1.45hsCRP>3(mg/L)0.280.25−1.670.100.07–1.25
BMI (kg/m2)1.070,130.560.570.85–1.35BMI (kg/m2)1.090.130.670.500.85–1.38
WC (cm)0.980.050.050.690.90–1.08WC (cm)0.980.05−0.540.590.89–1.07
TC (mg/dL)0.980.02−0.530.600.94–1.03TC/HDL–C0.410.62−0.590.560.02–7.88
HDL–C(mg/dL)1.020.030.820.970.97–1.09TG/HDL–C0.890.20−0.530.600.57–1.38
LDL–C(mg/dL)1.010.020.520.970.97–1.06LDL–C/HDL–C1.953.060.420.670.09–42.44
TG (mg/dL)0.990.01−0.700.990.99–1.01
Age (years)1.040.060.640.530.93–1.16Age (years)1.030.060.560.580.92–1.15
Smoking0.980.66−0.330.980.26–3.68Smoking1.070.730.110.910.29–4.05
Sex (Female)0.320.24−1.520.130.07–1.40Sex (Female)0.270.21−1.680.090.06–1.24
SBP (mm/Hg)1.010.020.840.400.98–1.06SBP (mm/Hg)1.020.020.870.380.98–1.06
Duration of HT (years)0.970.07−0.380.700.86–1.11Duration of HT (years)0.980.07−0.360.710.86–1.11
_cons0.030.13−0.770.442.73–262.33_cons0.381.77−0.210.840.0004–3322.67

The spearman's rank correlation coefficients(rs) mean MPOD between parameters_

Parameters (n=62)Mean MPOD (d.u.)

rP
hsCRP>3 (mg/L)−0.260.04*
BMI (kg/m2)−0.130.32
WC (cm)−0.010.94
TC (mg/dL)0.030.84
HDL–C (mg/dL)0.170.20
LDL–C (mg/dL)0.100.46
TG (mg/dL)−0.190.13
TC/HDL–C−0.100.44
TG/HDL–C−0.180.17
LDL–C/HDL–C0.010.98
Age (years)−0.0030.98
Duration of HT (years)−0.060.66
SBP (mm/Hg)−0.050.73
DBP (mm/Hg)0.090.47

Basic characteristics of participants by mean ± SD, min_ and max_

Parameters (n = 62)Mean ± SDMin.Max.
Systolic blood pressure (mm/Hg)138.77 ± 13.97104169
Diastolic blood pressure (mm/Hg)96.68 ± 14.0965129
Duration of hypertension(years)4.07 ± 4.940.1626
Body Mass Index (kg/m2)27.49 ± 5.461742.9
Waist Circumference (cm)92.00 ± 14.2364150
hsCRP (mg/L)2.70 ± 3.350.218.6
TC (mg/dL)192.31 ± 40.91108283
HDL-C(mg/dL)52.21 ± 15.8730114
LDL-C (mg/dL)118.79 ± 37.6052213
Triglyceride (mg/dL)161.26 ± 133.92431055
TC/HDL-C3.88 ± 1.061.896.91
TG/HDL-C3.50 ± 3.320.3824.53
LDL-C/HDL-C2.41 ± 0.870.844.94
Age (years)52.66 ± 5.323559
Right estimate MPOD (d.u.)0.48 ± 0.150.190.9
Left estimate MPOD (d.u.)0.49 ± 0.150.140.82
Mean estimated MPOD (d.u.)0.48 ± 0.140.220.84
DOI: https://doi.org/10.2478/abm-2023-0054 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 144 - 149
Published on: Oct 9, 2023
Published by: Chulalongkorn University
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2023 Chunchuree Kongmeesuk Kaneko, Katsunori Kaneko, Vitoon Jularattanaporn, Thamthiwat Nararatwanchai, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution 4.0 License.