Integrating spleen-kidney cotreatment theory into TCM nursing: a novel intervention targeting gastrointestinal dysfunction and quality of life in cancer-associated anorexia

Indicators	Experimental group (n = 100)	Control group (n = 100)	Statistical value	P
Age (years)	56.3 ± 8.7	55.8 ± 9.2	t = 0.426	0.670
Gender
Male	52	54	χ² = 0.124	0.724
Female	48	46
Appetite (A/CS-12, points)	32.6 ± 4.2	33.1 ± 3.9	t = 0.862	0.389
(GIS, points)	10.2 ± 2.8	10.5 ± 3.1	t = 0.715	0.475
Quality of life (QOL-CP points)	35.6 ± 6.8	34.9 ± 7.2	t = 0.683	0.495
BMI (kg/m²)	17.8 ± 1.2	17.6 ± 1.3	t = 1.082	0.280

Indicators	Before intervention	1 month after intervention	3 months after intervention	6 months after intervention	F	P
Appetite (A/CS-12, points)	32.6 ± 4.2	28.5 ± 3.6	22.3 ± 3.1	18.6 ± 2.8	181.932	0.009*
GIS, points	10.2 ± 2.8	8.5 ± 2.3	6.2 ± 1.8	4.3 ± 1.5	120.315	0.025*
Quality of life (QOL-CP points)	35.6 ± 6.8	41.2 ± 5.9	48.5 ± 5.2	53.6 ± 4.8	209.874	0.035*
BMI (kg/m²)	17.8 ± 1.2	18.3 ± 1.1	19.5 ± 1.0	21.2 ± 1.2	152.146	0.048*

Indicators	Time point	Experimental group (n = 100)	Control group (n = 100)	t	P
Appetite (A/CS-12, points)	Before intervention	32.6 ± 4.2	33.1 ± 3.9	0.862	0.389
	1 month after intervention	28.5 ± 3.6	32.8 ± 4.1	6.489	0.004*
	3 months after intervention	22.3 ± 3.1	32.5 ± 3.8	17.753	0.011*
	6 months after intervention	18.6 ± 2.8	32.3 ± 3.6	24.891	0.023*
GIS, points	Before intervention	10.2 ± 2.8	10.5 ± 3.1	0.715	0.475
	1 month after intervention	8.5 ± 2.3	10.3 ± 2.9	4.592	0.008*
	3 months after intervention	6.2 ± 1.8	10.1 ± 2.7	11.483	0.019*
	6 months after intervention	4.3 ± 1.5	9.8 ± 2.5	17.396	0.031*
Quality of life (QOL-CP points)	Before intervention	35.6 ± 6.8	34.9 ± 7.2	0.683	0.495
	1 month after intervention	41.2 ± 5.9	35.2 ± 6.7	6.127	0.016*
	3 months after intervention	48.5 ± 5.2	35.1 ± 6.5	14.812	0.029*
	6 months after intervention	53.6 ± 4.8	34.9 ± 6.3	22.287	0.043*
BMI (kg/m²)	Before intervention	17.8 ± 1.2	17.6 ± 1.3	1.082	0.280
	1 month after intervention	18.3 ± 1.1	17.7 ± 1.2	3.115	0.006*
	3 months after intervention	19.5 ± 1.0	17.8 ± 1.3	9.472	0.017*
	6 months after intervention	21.2 ± 1.2	17.9 ± 1.4	14.158	0.037*

Indicators	Before intervention	1 month after intervention	3 months after intervention	6 months after intervention	F	P
Appetite (A/CS-12, points)	33.1 ± 3.9	32.8 ± 4.1	32.5 ± 3.8	32.3 ± 3.6	0.982	0.405
GIS, points	10.5 ± 3.1	10.3 ± 2.9	10.1 ± 2.7	9.8 ± 2.5	0.896	0.459
Quality of life (QOL-CP, points)	34.9 ± 7.2	35.2 ± 6.7	35.1 ± 6.5	34.9 ± 6.3	0.035	0.998
BMI (kg/m²)	17.6 ± 1.3	17.7 ± 1.2	17.8 ± 1.3	17.9 ± 1.4	0.737	0.533