
Endocrine, Lifestyle, and Genetic Factors in the Development of Metabolic Syndrome
Abstract
Metabolic syndrome (MetS) is a chronic, multi-component disease characterised by central obesity, hyperglycaemia, dyslipidaemia, and hypertension. Since MetS leads to type 2 diabetes, cardiovascular disease, development of certain cancers, and eventually to premature death, it is not surprising that it draws the attention of scientists around the world. The aetiopathology of MetS is complex and still not fully understood. This review focuses on the role of endocrine factors such as cortisol and insulin in the development of MetS. It also takes a look at some of the contributing lifestyle and genetic factors as well as at the current knowledge about its treatment.
© 2013 Zorana Slanovic-Kuzmanović, Ivan Kos, Ana-Marija Domijan, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.