Skip to main content
Have a personal or library account? Click to login
Antioxidants in Organophosphorus Compounds Poisoning Cover

Antioxidants in Organophosphorus Compounds Poisoning

Archives of Industrial Hygiene and Toxicology
Volume 64 (2013): Issue 1 (March 2013)
By: ,  ,   and    
Open Access
|Mar 2013
References

References

  1. 1. Eddleston M, Eyer P, Worek F, Mohamed F, Senarathna L, von Meyer L, Juszczak E, Hittarage A, Azhar S, Dissanayake W, Sheriff MH, Szinicz L, Dawson AH, Buckley NA. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet 2005;366:1452-9.
    Open DOISearch in Google Scholar
  2. 2. Rosenbaum C, Bird SB. Non-muscarinic therapeutic targets for acute organophosphorus poisoning. J Med Toxicol 2010;6:408-12.
    Open DOISearch in Google Scholar
  3. 3. The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009 [displayed 6 September 2012]. Available at http://www.inchem.org/documents/pds/pdsother/class_2009.pdf
    Search in Google Scholar
  4. 4. Yang CC, Deng JF. Intermediate syndrome following organophosphate insecticide poisoning. J Chin Med Assoc 2007;70:467-72.
    Open DOISearch in Google Scholar
  5. 5. Petroianu GA. Poisoning with organophosphorus compounds (OPC): Mythology vs Reality. The Middle East J Emer Med 2007;6:3-8.
    Search in Google Scholar
  6. 6. Rahimi R, Nikfar S, Abdollahi M. Increased morbidity and mortality in acute human organophosphate-poisoned patients treated by oximes: a metaanalysis of clinical trials. Hum Exp Toxicol 2006;25:157-62.
    Open DOISearch in Google Scholar
  7. 7. Wetherell J, Price M, Mumford H, Armstrong S, Scott L. Development of next generation medical countermeasures to nerve agent poisoning. Toxicology 2007;233:120-7.
    Open DOISearch in Google Scholar
  8. 8. Pajoumand A, Shadnia S, Rezaie A, Abdi M, Abdollahi M. Benefits of magnesium sulfate in the management of acute human poisoning by organophosphorus insecticides. Hum Exp Toxicol 2004;23:565-9.
    Open DOISearch in Google Scholar
  9. 9. Shadnia S, Ashrafivand S, Mostafalou S, Abdollahi M. Nacetylcysteine a novel treatment for acute human organophosphate poisoning. Int J Pharmacol 2011;7:732-5.
    Open DOISearch in Google Scholar
  10. 10. Peter JV, Moran JL, Graham PL. Advances in the management of organophosphate poisoning. Expert Opin Pharmacother 2007;8:1451-64.
    Open DOISearch in Google Scholar
  11. 11. Balali-Mood M, Saber H. Recent advances in the treatment of organophosphorus poisonings. Iran J Med Sci 2012;37:74-91.
    Search in Google Scholar
  12. 12. Blain PG. Organophosphorus poisoning (acute). Clin Evid (Online) 2011;2102.
    Search in Google Scholar
  13. 13. Lallement G, Baubichon D, Clarencon D, Galonnier M, Peoc’h M, Carpentier P. Review of the value of gacyclidine (GK-11) as adjuvant medication to conventional treatments of organophosphate poisoning: primate experiments mimicking various scenarios of military or terrorist attack by soman. Neurotoxicology 1999;20:675-84.
    Search in Google Scholar
  14. 14. Mohammadi H, Karimi G, Seyed Mahdi Rezayat, Ahmad Reza Dehpour, Shafiee H, Nikfar S, Baeeri M, Sabzevari O, Abdollahi M. Benefit of nanocarrier of magnetic magnesium in rat malathion-induced toxicity and cardiac failure using non-invasive monitoring of electrocardiogram and blood pressure. Toxicol Ind Health 2011;27:417-29.
    Open DOISearch in Google Scholar
  15. 15. Abdollahi M, Ranjbar A, Shadnia S, Nikfar S, Rezaie A. Pesticides and oxidative stress: a review. Med Sci Monit 2004;10:RA141-7.
    Search in Google Scholar
  16. 16. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 3rd ed. Oxford: Oxford University Press; 1999.
    Search in Google Scholar
  17. 17. Dandapani M, Zachariah A, Kavitha MR, Jeyaseelan L, Oommen A. Oxidative damage in intermediate syndrome of acute organophosphorus poisoning. Indian J Med Res 2003;117:253-9.
    Search in Google Scholar
  18. 18. Vidyasagar J, Karunakar N, Reddy MS, Rajnarayana K, Surender T, Krishna DR. Oxidative stress and antioxidant status in acute organophosphorus insecticide poisoning. Indian J Pharmacol 2004;36:76-9.
    Search in Google Scholar
  19. 19. Possamai FP, Fortunato JJ, Agostinho J, Quevedo D, Wilhelm FF, Dal-Pizzol F. Oxidative stress after acute and sub-chronic malathion intoxication in Wistar rats. Environ Toxicol Pharmacol 2007;23:198-204.
    Open DOISearch in Google Scholar
  20. 20. Ranjbar A, Solhi H, Mashayekhi FJ, Susanabdi A, Rezaie A, Abdollahi M. Oxidative stress in acute human poisoning with organophosphorus insecticides; a case control study. Environ Toxicol Pharmacol 2005;20:88-91.
    Open DOISearch in Google Scholar
  21. 21. Shadnia S, Dasgar M, Taghikhani S, Mohammadirad A, Khorasani R, Abdollahi M. Protective effects of alphatocopherol and N-acetylcysteine on diazinon-induced oxidative stress and acetylcholinesterase inhibition in rats. Toxicol Mech Methods 2007;17:109-15.
    Open DOISearch in Google Scholar
  22. 22. Kovacic P. Mechanism of organophosphates (nerve gases and pesticides) and antidotes: electron transfer and oxidative stress. Curr Med Chem 2003;10:2705-9.
    Open DOISearch in Google Scholar
  23. 23. Pena-Llopis S. Antioxidants as potentially safe antidotes for organophosphorus poisoning. Curr Enzyme Inhib 2005;1:147-56.
    Open DOISearch in Google Scholar
  24. 24. Lukaszewicz-Hussain A. Role of oxidative stress in organophosphate insecticide toxicity - Short review. Pest Biochem Physiol 2010;98:145-50.
    Open DOISearch in Google Scholar
  25. 25. Soltaninejad K, Abdollahi M. Current opinion on the science of organophosphate pesticides and toxic stress: a systemic review. Med Sci Monit 2009;15:RA75-90.
    Search in Google Scholar
  26. 26. Karami-Mohajeri S, Abdollahi M. Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review. Hum Exp Toxicol 2011;30:1119-40.
    Open DOISearch in Google Scholar
  27. 27. Bayrami M, Hashemi T, Malekirad AA, Ashayeri H, Faraji F, Abdollahi M. Electroencephalogram, cognitive state, psychological disorders, clinical symptom, and oxidative stress in horticulture farmers exposed to organophosphate pesticides. Toxicol Indl Health 2012;28:90-6.
    Open DOISearch in Google Scholar
  28. 28. Cankayali I, Demirag K, Eris O, Ersoz B, Moral AR. The effects of N-acetylcysteine on oxidative stress in organophosphate poisoning model. Adv Ther 2005;22:107-16.
    Open DOISearch in Google Scholar
  29. 29. Puntel GO, de Carvalho NR, Gubert P, Palma AS, Dalla Corte CL, Avila DS, Pereira ME, Carratu VS, Bresolin L, da Rocha JB, Soares FA. Butane-2, 3-dionethiosemicarbazone: an oxime with antioxidant properties. Chem Biol Interact 2009;177:153-60.
    Open DOISearch in Google Scholar
  30. 30. Yurumez Y, Cemek M, Yavuz Y, Birdane YO, Buyukokuroglu ME. Beneficial effect of N-acetylcysteine against organophosphate toxicity in mice. Biol Pharm Bull 2007;30:490-4.
    Open DOISearch in Google Scholar
  31. 31. Pena-Llopis S, Ferrando MD, Pena JB. Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine. Aquat Toxicol 2003;65:337-60.
    Open DOISearch in Google Scholar
  32. 32. Gunay N, Kose A, Tarakcioglu M, Gunay NE, Demiryurek AT. Evaluation of cardiac oxidative stress parameters and mortality in a rat model of organophosphate poisoning. J Emerg Med 2007;33:338.
    Open DOISearch in Google Scholar
  33. 33. Kose A, Gunay N, Kose B, Ocak AR, Erel O, Demiryurek AT. Effects of atropine and pralidoxime pretreatment on serum and cardiac oxidative stress parameters in acute dichlorvos toxicity in rats. Pest Biochem Physiol 2010;97:249-55.
    Open DOISearch in Google Scholar
  34. 34. Nurulain SM, Kalasz H, Adem A, Petroianu G. Antioxidant has no role in survival of rats after intoxication with acute dose of paraoxon. In: 5th International Online Medical Conference (IOMC 2012); 3-11 March 2012; Abstract 147.
    Search in Google Scholar
  35. 35. Venkatesh S, Kavitha ML, Zachariah A, Oommen A. Progression of type I to type II paralysis in acute organophosphorus poisoning: is oxidative stress significant? Arch Toxicol 2006;80:354-61.
    Search in Google Scholar
  36. 36. Abdollahi M, Karami-Mohajeri S. A comprehensive review on experimental and clinical findings in intermediate syndrome caused by organophosphorus poisoning. Toxicol Appl Pharmacol 2012;258:309-14.
    Open DOISearch in Google Scholar
  37. 37. Srivastava A, Shivanandappa T. Differential cholinesterase inhibition in the rat brain regions by dichlorvos and protective effect of Decalepis hamiltonii roots. Neurotoxicology 2011;32:931-4.
    Open DOISearch in Google Scholar
  38. 38. Bhatti GK, Bhatti JS, Kiran R, Sandhir R. Biochemical and morphological perturbations in rat erythrocytes exposed to ethion: protective effect of vitamin E. Cell Mol Biol (Noisyle- grand) 2011;57:70-9.
    Search in Google Scholar
  39. 39. Amara IB, Soudani N, Troudi A, Bouaziz H, Boudawara T, Zeghal N. Antioxidant effect of vitamin E and selenium on hepatotoxicity induced by dimethoate in female adult rats. Ecotoxicol Environ Saf 2011;74:811-9.
    Open DOISearch in Google Scholar
  40. 40. Dwivedia N, Flora SJS. Concomitant exposure to arsenic and organophosphates on tissue oxidative stress in rats. Food Chem Toxicol 2011;49:1152-9.
    Open DOISearch in Google Scholar
  41. 41. Dirican EK, Kalender Y. Dichlorvos-induced testicular toxicity in male rats and the protective role of vitamins C and E. Exp Toxicol Pathol 2012;64:821-30.
    Open DOISearch in Google Scholar
  42. 42. Ojha A, Yaduvanshi SK, Pant SC, Lomash V, Srivastava N. Evaluation of DNA damage and cytotoxicity induced by three commonly used organophosphate pesticides individually and in mixture, in rat tissues. Environ Toxicol 2011; doi: 10.1002/tox.20748 [Epub ahead of print].
    Open DOISearch in Google Scholar
  43. 43. Ehrich M, Van Tassell R, Li Y, Zhou Z, Kepley CL. Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro. Toxicol In Vitro 2011;25:301-17.
    Open DOISearch in Google Scholar
  44. 44. Lua L, Xiuli Wangb X, Liwei Langa L, Fu F. Protective effect of reduced glutathione on the liver injury induced by acute omethoate poisoning. Environ Toxicol Pharmacol 2010;30:279-83.
    Open DOISearch in Google Scholar
  45. 45. Cemek M, Emin BM, Yurumez Y, Yavuz Y, Aslan A, Buyukben A, Aymelek F. Tissue trace and major element levels in organophosphate insecticide fenthion (Lebaycid) toxicity in rats: prophylactic and therapeutic effect of exogenous melatonin. Ecotoxicol Environ Saf 2010;73:206-12.
    Open DOISearch in Google Scholar
  46. 46. Shah MD, Iqbal M. Diazinon-induced oxidative stress and renal dysfunction in rats. Food Chem Toxicol 2010;48:3345-53.
    Open DOISearch in Google Scholar
  47. 47. Uzun FG, Demir F, Kalender S, Bas H, Kalender Y. Protective effect of catechin and quercetin on chlorpyrifosinduced lung toxicity in male rats. Food Chem Toxicol 2010;48:1714-20.
    Open DOISearch in Google Scholar
  48. 48. Kalender S, Uzun FG, Durak D, Demir F, Kalender Y. Malathion-induced hepatotoxicity in rats: the effects of vitamins C and E. Food Chem Toxicol 2010;48:633-8.
    Open DOISearch in Google Scholar
  49. 49. Mansour SA, Mossa AH. Adverse effects of lactational exposure to chlorpyrifos in suckling rats. Hum Exp Toxicol 2010;29:77-92.
    Open DOISearch in Google Scholar
  50. 50. Togun N, Kose A, Gunay N, Tarakcioglu M, Demiryurek AT. Formulation of effects of atropine, pralidoxime and magnesium sulfate on cardiac tissue levels of nitric oxide, malondialdehyde and glutathione in organophosphate poisoning using artificial neural network. Comput Biol Med 2010;40:29-36.
    Open DOISearch in Google Scholar
  51. 51. Sharma Y, Bashir S, Irshad M, Gupta SD, Dogra TD.
    Search in Google Scholar
  52. Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats. Toxicology 2005;206:49-57.
    Open DOISearch in Google Scholar
  53. 52. Fortunato JJ, Feier G, Vitali AM, Petronilho FC, Dal- Pizzol F, Quevedo J. Malathion-induced oxidative stress in rat brain regions. Neurochem Res 2006;31:671-8.
    Open DOISearch in Google Scholar
  54. 53. Jiang N, Lu L, Wang T, Zhang L, Xin W, Fu F. Reduced glutathione attenuates liver injury induced by methyl parathion in rats. Toxicol Mech Methods 2010;20:69-74.
    Open DOISearch in Google Scholar
  55. 54. Zhang JW, Lv GC, Zhao Y. The significance of the measurement of serum xanthenes oxidase and oxidation markers in patients with acute organophosphorus pesticide poisoning. J Int Med Res 2010;38:458-65.
    Open DOISearch in Google Scholar
  56. 55. Rastogi SK, Satyanarayan PVV, Ravishankar D, Tripathi S. A study on oxidative stress and antioxidant status of agricultural workers exposed to organophosphorus insecticides during spraying. Indian J Occup Environ Med 2009;13:131-4.
    Open DOISearch in Google Scholar
  57. 56. Hundekari IA, Suryakar AN, Rathi DB. Oxidative stress and antioxidant status in acute organophosphorus pesticides poisoning cases of North Karnataka (India). J Environ Health Res 2011;11:39-44.
    Search in Google Scholar
DOI: https://doi.org/10.2478/10004-1254-64-2013-2294 | Journal eISSN: 1848-6312 (formerly 0004-1254) | Journal ISSN: 0004-1254
Journal RSS Feed
Language: English
Page range: 169 - 177
Published on: Mar 26, 2013
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Keywords:
acute poisoning,
oxidative stress,
survival study
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2013 Syed M Nurulain, Peter Szegi, Kornèlia Tekes, Syed Nh Naqvi, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 64 (2013): Issue 1 (March 2013)
Previous article
Next article