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Severe Renal Function Impairment in Adult Patients Acutely Poisoned with Concentrated Acetic Acid Cover

Severe Renal Function Impairment in Adult Patients Acutely Poisoned with Concentrated Acetic Acid

Open Access
|Mar 2013

Abstract

Acetic acid is a widely used organic acid with corrosive properties that depend on its concentration. If acetic acid is ingested in concentrations above 30 % it may severely damage the upper gastrointestinal tract and cause intravascular haemolysis, which can result in severe kidney and liver disorders and disseminated intravascular coagulation. In this retrospective study, we analysed acetic acid ingestion data collected at the University Clinic for Toxicology of Skopje, Macedonia from 1 January 2002 to 31 December 2011. The analysis included systemic complications, kidney damage, and the outcomes in particular. Over the ten years, 84 patients were reported at the Clinic to have ingested highly concentrated acetic acid. Twenty-eight developed kidney disorders, while the remaining 56 had no complications. Fatal outcome was reported for 11 patients, seven of whom had systemic complications and four severe gastrointestinal complications.

DOI: https://doi.org/10.2478/10004-1254-64-2012-2275 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
Language: English, Croatian, Slovenian
Page range: 153 - 158
Published on: Mar 26, 2013
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2013 Andon Chibishev, Aleksandar Sikole, Zanina Pereska, Vesna Chibisheva, Natasha Simonovska, Nikola Orovchanec, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.