Have a personal or library account? Click to login
Altered canonical hedgehog-gli signalling axis in pesticide-induced bone marrow aplasia mouse model Cover

Altered canonical hedgehog-gli signalling axis in pesticide-induced bone marrow aplasia mouse model

Open Access
|Sep 2012

References

  1. 1. Elliot T. Established pyrethroid insecticides. Pestic Sci 1980;11:119-28.10.1002/ps.2780110204
  2. 2. Tabarean IV, Narahashi T. Potent modulation of tetradotoxinsensitive and tetradotoxin-resistant sodium channels by the type II pyrethroid deltamethrin. J Pharmacol Exp Ther 1998;284:958-65.
  3. 3. Chandra S, Saxena PN, Gupta SK. In vivo cytogenetic effects of a commercially formulated mixture of cypermethrin and quinalphos in mice. Mutat Res 2005;587:120-5.10.1016/j.mrgentox.2005.08.004
  4. 4. Chauhan LK, Kumar M, Paul BN, Goel SK, Gupta SK. Cytogenetic effects of commercial formulations of deltamethrin and/or isoproturon on human peripheral lymphocytes and mouse bone marrow cells. Environ Mol Mutagen 2007;48:636-43.10.1002/em.20330
  5. 5. Celik A, Mazmancı B, Camlıca Y, Comelekoğlu Y, Askın A. Evaluation of cytogenetic effects of k-cyhalothrin in wistar rat bone marrow by gavage administration. Ecotoxicol Environ Saf 2005;61:128-33.10.1016/j.ecoenv.2004.07.009
  6. 6. Celik A, Mazmancı B, Camlıca Y, Askın A, Comelekoğlu U. Induction of micronuclei by k-cyhalothrin in wistar rat bone marrow and gut epithelial cells. Mutagenesis 2005;20:125-9.10.1093/mutage/gei020
  7. 7. Giri A, Giri S, Sharma GD. Malathion and fenvalerate induce micronuclei in mouse bone marrow cells. Environ Mol Mutagen 2011;52:607-13.10.1002/em.20649
  8. 8. Jamil K, Shaik AP, Mahboob M, Krishna D. Effect of organophosphorus and organochlorine pesticides (monocrotophos, chloropyriphos, dimethoate and endosulfan) on human lymphocyte cultures 2004;27:133-44.
  9. 9. Shukla Y, Yadav A, Arora A. Carcinogenic and cocarcinogenic potential of cypermethrin on mouse skin. Cancer Lett 2002;182:33-41.10.1016/S0304-3835(02)00077-0
  10. 10. Litchfi eld MH. Toxicity to mammals. In: Leahey JP, editors. The pyrethroid insecticides. London: Taylor & Francis; 1985. p. 99-149.
  11. 11. Broughton A, Thrasher JD, Madison R. Chronic health effects and immunological alterations associated with exposure to pesticides. Comments Toxicol 1990;4:59-71.
  12. 12. Holladay SD, Luster MI. Alterations in fetal thymic and liver hematopoietic cells as indicators of exposure to developmental immunotoxicants. Environ Health Perspect 1996;104(Suppl 4):809-13.10.1289/ehp.96104s480914696678880003
  13. 13. Repetto R, Baliga SS. Pesticide and immunosuppression: the risks to public health. Health Policy Plan 1997;12:97-106.10.1093/heapol/12.2.9710168201
  14. 14. Kevin Y, Urayama JK, Wiencke B, Chokkalingam AP, Metayer C, Wiemels JL. MDR1 Gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev 2007;16:1172-7.10.1158/1055-9965.EPI-07-000717548681
  15. 15. Ledirac N, Antherieu S, Uby AD, Caron JC, Rahmani R. Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species. Toxicol Sci 2005;86:444-52.10.1093/toxsci/kfi192
  16. 16. Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, David A. Stevens DA, Beachy PA. Itraconazole, a commonly used antifungal that inhibits hedgehog pathway activity and cancer growth. Cancer Cell 2010;17:388-99.10.1016/j.ccr.2010.02.027
  17. 17. Laryea D, Gullbo J, Isaksoon A, Larsson R, Nygren P. Characterization of the cytotoxic properties of the benzimidazole fungicide, benomyl and carbendazim, in human tumor cell lines and primary culture of patient tumor cells. Anticancer Drugs 2010;21:33-4210.1097/CAD.0b013e328330e74e
  18. 18. Young NS, Issaragrisil S, Ch’en WC, Takaku F. Aplastic anemia in the Orient. Br J Haematol 1986;62:1-6.10.1111/j.1365-2141.1986.tb02893.x
  19. 19. Muir KR, Chilvers CED, Harriss C, Coulson L, Grainge M, Darbyshire P, Geary CJ, Hows J, Marsh T, Rutherford M, Taylor E, Gordon-Smith EC. The role of occupational and environmental exposures in the aetiology of acquired severe aplastic anaemia: a case control investigation. Br J Haematol 2003;123:906-14.10.1046/j.1365-2141.2003.04718.x
  20. 20. Fleming LE, Timmeny W. Aplastic anemia and pesticides. An etiologic association? J Occup Med 1993;35:1106-16.
  21. 21. Botnick LE, Hannon EC, Hellman S. A long lasting proliferative defect in the hematopoietic stem cell compartment following cytotoxic agents. Int J Radiat Oncol Biol Phys 1979;5:1621-5.10.1016/0360-3016(79)90785-5
  22. 22. Prihartono N, Kriebel D, Woskie S, Thetkhathuek A, Sripaung N, Padungtod C, Kaufman D. Risk of aplastic anemia and pesticide and other chemical exposures. Asia Pac J Public Health 2011;23:369-77.10.1177/101053951140360521490113
  23. 23. Rugman FP, Cosstic R. Aplastic anemia associated with organochlorine pesticides: Case reports and review of evidence. J Clin Pathol 1990;43:98-101.10.1136/jcp.43.2.985022871690760
  24. 24. Sanchez-Medal L, Castando JP, Garcia-Rojas F. Insecticides and aplastic anemia. N Engl J Med 1963;269:1365-7.10.1056/NEJM19631219269250814064322
  25. 25. Wang HH, Grufferman S. Aplastic anemia and occupational pesticide exposure: a case control study. J Occup Med 1981;23:364-6.
  26. 26. Rau ATK, Coutinho A, Avabratha KS, Rau AR, Warrier RP. Pesticide (endosulfan) levels in the bone marrow of children with hematological malignancies. Indian Pediatr 2012;49:113-7.10.1007/s13312-012-0025-521992855
  27. 27. Chatterjee S, Basak P ,Chaklader M, Das P, Pereira JA, Chaudhuri S, Law S. Pesticide induced marrow toxicity and effects on marrow cell population and on hematopoietic stroma. Exp Toxicol Pathol 2011 Oct 15. [Epub ahead of print]
  28. 28. Chatterjee S, Chaklader M, Basak P, Das P, Das M, Pereira JA, Dutta RK, Chaudhuri S, Law S. An animal model of chronic aplastic bone marrow failure following pesticide exposure in mice. Int J Stem Cells 2010;3:54-62.10.15283/ijsc.2010.3.1.54
  29. 29. Law S, Basu K, Banerjee S, Begum B, Chaudhuri S. Cord blood derived plasma factor (CBPF) potentiated the low cytokinetic and immunokinetic profi le of bone marrow cells in pesticide victims suffering from Acquired Aplastic Anaemia (AAA): an 2006;35:209-25.
  30. 30. Nusslein-Volhard C, Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980;287:795-801.10.1038/287795a0
  31. 31. Roy S, Ingham PW. Hedgehogs tryst with the cell cycle. J Cell Sci 2002;115:4393-97.10.1242/jcs.00158
  32. 32. Kalderon D. Transducing the hedgehog signal. Cell 2000;103:371-4.10.1016/S0092-8674(00)00129-X
  33. 33. Taipale J, Cooper MK, Maiti T, Beachy PA. Patched acts catalytically to suppress the activity of Smoothened. Nature 2002;418:892-7.10.1038/nature00989
  34. 34. Adolphe C, Hetherington R, Ellis T, Wainwright B. Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res 2006;66:2081-8.10.1158/0008-5472.CAN-05-2146
  35. 35. Lee J, Platt KA, Censullo P, Ruiz I, Altaba A. Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 1997;124:2537-52.10.1242/dev.124.13.2537
  36. 36. Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996;86:897-906.10.1016/S0092-8674(00)80165-8
  37. 37. Farrington SM, Belaoussoff M, Baron MH. Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev 1997;62:197-211.10.1016/S0925-4773(97)00664-3
  38. 38. Dyer MA, Farrington SM, Mohn D, Munday JR, Baron MH. Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 2001;128:1717-30.10.1242/dev.128.10.171711311154
  39. 39. Cridland SO, Keys JR, Papathanasiou P, Perkins AC. Indian hedgehog supports defi nitive erythropoiesis. Blood Cells Mol Dis 2009;43:149-55.10.1016/j.bcmd.2009.04.00419443245
  40. 40. Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstong SA, Ghilardi N, Gould S, Sauvage FJ, McMahon AP, Gilliland DG. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell 2009;4:559-67.10.1016/j.stem.2009.03.016306532319497284
  41. 41. Gao J, Graves S,Koch U, Liu S, Jankovic V,Buonamici S, Andaloussi AE, Nimer SD, Kee BL, Taichman R, Radtke F, Aifantis I. Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell 2009;4:548-58.10.1016/j.stem.2009.03.015291468819497283
  42. 42. Merchant AA, Matsui W. Smoothening the controversial role of hedgehog in hematopoiesis. Cell Stem Cell 2009;4:470-1.10.1016/j.stem.2009.05.006423409919497273
  43. 43. Mar BG, Amakye D, Aifantis I, Buonamici S. The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis. Leukemia 2011;25:1665-73.10.1038/leu.2011.143431048021660044
  44. 44. Trowbridge JJ, Scott MP, Bhatia. M. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proc Natl Acad Sci USA 2006;103:14134-9.10.1073/pnas.0604568103159992416968775
  45. 45. Dierks C, Beigi R, Guo GR, Zirlik K, Stegert MR, Manley P, Trussell C, Graeff AS, Landwerlin K, Veelken H, Warmuth M. Expansion of Bcr-Abl-Positive leukemic stem cells is dependent on Hedgehog pathway activation. Cancer Cell 2008;14:238-49.10.1016/j.ccr.2008.08.00318772113
  46. 46. Zhao C, Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, Van Arsdale T, Beachy PA, Reya T. Hedgehog signaling is essential for maintenance of cancer stem cells in myeloid leukemia. Nature 2009;458:776-9.10.1038/nature07737294623119169242
  47. 47. Bhardwaj G, Murdoch B, Wu D, Baker DP, Williams KP, Chadwick K, Ling LE, Karanu FN, Bhatia M. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nature Immunol 2001;2:172-80.10.1038/8428211175816
  48. 48. Detmer K, Thompson AJ, Garner RE, Walker AN, Gaffi eld W, Dannaw H. Hedgehog signaling and cell cycle control in differentiating erythroid progenitors. Blood Cells Mol Dis 2005;34:60-70.10.1016/j.bcmd.2004.08.02615607701
  49. 49. Merchant A, Joseph G, Wang O, Brennan S, Matsui W. Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors. Blood 2010;115:2391-6.10.1182/blood-2009-09-241703284589720107231
  50. 50. Sengupta A, Banerjee D, Chandra S, Banerji SK, Ghosh R, Roy R, Banerjee S. Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression. Leukemia 2007;21:949-55.10.1038/sj.leu.240465717361218
  51. 51. Bai L-Y, Chiu C-F, Lin C-W, Hsu N-Y, Lin C-L, Lo W-J, Kao M-C. Differential expression of Sonic hedgehog and Gli1 in hematological malignancies. Leukemia 2008;22:226-8.10.1038/sj.leu.240497817928882
  52. 52. Chatterjee S, Basak P, Das M, Das P, Pereira JA, Dutta RK, Chaklader M, Chaudhuri S, Law S. Kinetic impairment of haemopoietic stem cells in experimentally induced leukemia and aplastic anemia: an inverse correlation. J Stem Cells 2009;4:179-89.
  53. 53. Queiroz MLS, da Rocha MC, Torello CO, Queiroz JS, Bincoletto C, Morgano MA, Romano MR, Paredes-Gamero EJ, Barbosa CMV, Calgarotto AK. Chlorella vulgaris restores bone marrow cellularity and cytokine production in leadexposed mice. Food Chem Toxicol 2011;49:2934-41.10.1016/j.fct.2011.06.05621820028
  54. 54. The Niche. Hematopoiesis, no hedgehog needed [displayed 26 July 2012]. Available at http://blogs.nature.com/theniche/2009/06/hematopoiesis_no_hedgehog_need.html
DOI: https://doi.org/10.2478/10004-1254-63-2012-2255 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
Language: English, Croatian, Slovenian
Page range: 271 - 282
Published on: Sep 25, 2012
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2012 Malay Chaklader, Prosun Das, Jacintha Archana Pereira, Samaresh Chaudhuri, Sujata Law, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.