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Evaluation of Patulin Toxicity in the Thymus of Growing Male Rats Cover

Evaluation of Patulin Toxicity in the Thymus of Growing Male Rats

Archives of Industrial Hygiene and Toxicology
Volume 60 (2009): Issue 4 (December 2009)
By: Evrim Arzu Koçkaya,  Güdeniz Selmanoğlu,  Nesrin Özsoy and  Nursel Gül  
Open Access
|Jan 2010

References

  1. Harrison MA. Presence and stability of patulin in apple products: A review. J Food Safety 1989;9:147-53.10.1111/j.1745-4565.1988.tb00515.x
    Search in Google Scholar
  2. Paster N, Huppert D, Barkai-Golan R. Production of patulin by different strains of Penicillium expansum in pear and apple cultivars stored at different temperatures and modified atmospheres. Food Addit Contam 1995;12:51-8.10.1080/02652039509374278
    Search in Google Scholar
  3. Askar A. Patulin in apple juice and children's apple food. Fruit Proces 1999;3:74-7.
    Search in Google Scholar
  4. WHO - Joint FAO/WHO Expert Committee on Food Additives (JECFA). Position paper on patulin (prepared by France). The Hague, Netherlands. 9-13 March 1998.
    Search in Google Scholar
  5. Alves I, Oliveira NG, Laires A, Rodrigues AS, Rueff J. Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulator of patulin clastogenicity. Mutagenesis 2000;15:229-34.10.1093/mutage/15.3.229
    Search in Google Scholar
  6. Junquiera LC, Carnerio J, Kelley RO. Basic Histology. New York (NY): Prentice-Hall International Inc.; 1995.
    Search in Google Scholar
  7. Makinodan T, Kay MMB. Age influence on the immune system. Adv Immunol 1980;29:287-330.10.1016/S0065-2776(08)60047-4
    Search in Google Scholar
  8. Raviola E. Thymus. In: Bloom W, Fawcett DW, editors. A textbook of histology. Philadelphia: Saunders International Edition; 1986. p. 436-45.
    Search in Google Scholar
  9. Huff K, End D, Guroff G. Nerve growth factor-induced alteration in response of PC12 pheochromocytoma cell to epidermal growth factor. J Cell Biol 1981;88:189-98.10.1083/jcb.88.1.189
    Search in Google Scholar
  10. Le PT, Lazorich S, Whichard P, Haynes BF, Singer KH. Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factor-alfa regulate mRNA levels of interleukin 1 a (IL-1a), IL-1β, and IL-6 in human thymic epithelial cells at a post-transcriptional level. J Exp Med 1991;174:1147-57.10.1084/jem.174.5.1147
    Search in Google Scholar
  11. Nieburgs AC, Korn JH, Picciano PT, Cohen S. Thymic epithelium in vitro. IV. Regulation of growth and mediator production by epidermal growth factor. Cell Immunol 1987;108:396-404.10.1016/0008-8749(87)90222-X
    Search in Google Scholar
  12. Woodborn JR. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol Ther 1999;82:241-50.10.1016/S0163-7258(98)00045-X
    Search in Google Scholar
  13. Henley JD, Koukoulis GK, Loehrer PJ Sr. Epidermal growth factor receptor expression in invasive thymoma. J Cancer Res Clin Oncol 2002;128:167-70.10.1007/s00432-001-0319-911935304
    Search in Google Scholar
  14. Escoula L, Bourdiol D, Linas MD, Recco P, Seguela JP. Enhancing resistance and modulation of humoral immune response to experimental Candida albicans infection by patulin. Mycopathologica 1988;103:153-6.10.1007/BF004368143057378
    Search in Google Scholar
  15. Escoula L, Thomsen M, Bourdiol D, Pipy B, Peuriete S, Roubinet F. Patulin immunotoxicology: Effects on phagocyte activation and the cellular and humoral immune system of mice and rabbits. Int J Immunopharmacol 1988;10:983-9.10.1016/0192-0561(88)90045-8
    Search in Google Scholar
  16. Llewellyn GC, McCay JA, Brown RD, Musgrove DL, Butterworth LF, Munson AE, White KL. Immunological evaluation of the mycotoxin patulin in female B6C3F1 mice. Food Chem Toxicol 1998;36:1107-15.10.1016/S0278-6915(98)00084-2
    Search in Google Scholar
  17. Ostry V, Skarkova J, Ruprich J. Occurrence of Penicillium expansum and patulin in apples as raw materials for processing of foods - case study. Mycotox Res 2004;20:24-8.10.1007/BF02946705
    Search in Google Scholar
  18. Elcüan EA and Akay MT. Age-dependent immunolocalization of fibronectin and histological changes in the thymus of rats. Vet Res Commun 1998;22:525-32.10.1023/A:1006141719909
    Search in Google Scholar
  19. Hayat MA. Principles and Techniques of Electron Microscopy: Biological Applications. Vol 1, 2nd ed. Baltimore (MD): University Park Press; 1981.
    Search in Google Scholar
  20. Takeuchi Y, Kosaka T, Hayashi K, Takeda M, Yoshida T, Fujisawa H, Teramoto S, Maita K, Harada T. Thymic atrophy induced by methoxychlor in rat pups. Toxicol Lett 2002;135:199-207.10.1016/S0378-4274(02)00259-X
    Search in Google Scholar
  21. Selmanoğlu G, Koçaya EA. Investigation of the effects of patulin on thyroid and testis, and hormone levels in growing male rats. Food Chem Toxicol 2004;42:721-7.10.1016/j.fct.2003.12.007
    Search in Google Scholar
  22. Kuper CF, Beems RB, Hollanders VMH. Spontaneous pathology of the thymus in aging Wistar (Cpb:Wu) rats. Vet Pathol 1986;23:270-7.10.1177/030098588602300307
    Search in Google Scholar
  23. Utsuyama M, Hirokawa K. Hypertrophy of the thymus and restoration of immune functions in mice and rats by gonadectomy. Mech Ageing Dev 1989;47:175-85.10.1016/0047-6374(89)90030-4
    Search in Google Scholar
  24. Miller JF, Osoba D. Current concepts of the immunological function of the thymus. Physiol Rev 1967;47:437-520.10.1152/physrev.1967.47.3.437
    Search in Google Scholar
  25. Haynes BF. The human thymic microenvironment. Adv Immunol 1987;36:87-142.10.1016/S0065-2776(08)60900-1
    Search in Google Scholar
  26. Ichikawa J, Kiyohara T. Supression of EGF-induced cell proliferation by the blockade of Ca2+ mobilization and capacitative Ca2+ entry in mouse mammary epithelial cells. Cell Biochem Funct 2001;19:213-9.10.1002/cbf.914
    Search in Google Scholar
  27. Friedman L. Patulin: mycotoxin or fungal metabolite? (Current state of knowledge). Biodeterior Res 1990;3:21-54.10.1007/978-1-4757-9453-3_3
    Search in Google Scholar
  28. Riley RT, Showker JL. The mechanism of patulin's cytotoxicity and the antioxidant activity of indole tetramic acids. Toxicol Appl Pharmacol 1991;109:108-26.10.1016/0041-008X(91)90195-K
    Search in Google Scholar
  29. Saxena N, Ansari KM, Kumar R, Dhawan A, Dwivedi PD, Das M. Patulin causes DNA damage leading to cell cycle arrest and apoptosis through modulation of Bax, p53 and p21/WAF1 proteins in skin of mice. Toxicol Appl Pharmacol 2009;234:192-201.10.1016/j.taap.2008.09.033
    Search in Google Scholar
  30. Cooray R, Kiessling KH, Lindahl-Kiessling K. The effects of patulin and patulin cysteine mixtures on DNA synthesis and the frequency of sister-chromatid exchanges in human lymphocytes. Food Chem Toxicol 1982;20:893-8.10.1016/S0015-6264(82)80224-1
    Search in Google Scholar
  31. Sorenson WG, Gerberick GF, Lewis DM, Castranova V. Toxicity of mycotoxins for the rat pulmonary macrophage in vitro.Environ Health Persp 1986;66:45-53.10.1289/ehp.866645
    Search in Google Scholar
  32. Burghardt RC, Barhoumi R, Lewis EH, Bailey RH, Pyle KA, Clement BA, Phillips TD. Patulin-induced cellular toxicity: a vital fluorescence study. Toxicol Appl Pharmacol 1992;112:235-44.10.1016/0041-008X(92)90193-V
    Search in Google Scholar
  33. Nodera M, Yamagisawa H, Wada O. Increased apoptosis in a variety of tissues of zinc-deficient rats. Life Sci 2001;69:1639-49.10.1016/S0024-3205(01)01252-8
    Search in Google Scholar
  34. Gü N, Özsoy N, Osmanağaoğlu Ö, Selmanoğlu G, Koçaya EA. Effects of patulin on thymus capillary of rats. Cell Biochem Funct 2006;24:541-6.10.1002/cbf.126316142687
    Search in Google Scholar
  35. Özsoy N, Selmanoğlu G, Koçaya EA, Gü N, Cebesoy S. Effect of patulin on the interdigitating dendritic cells (IDCs) of rat thymus. Cell Biochem Funct 2008;26:192-6.10.1002/cbf.143117702051
    Search in Google Scholar
  36. Elmore SA. Enhanced histopathology of the thymus. Toxicol Pathol 2006;34:656-65.10.1080/01926230600865556
    Search in Google Scholar
  37. Sharma RP. Immunotoxicity of mycotoxins. J Dairy Sci 1993;76:892-7.10.3168/jds.S0022-0302(93)77415-9
    Search in Google Scholar
  38. World Health Organization (WHO). Food Additivies Series 35 [displayed 18 November 2009]. Available at http://www.inchem.org/documents/jecfa/jecmono/v35je01.htm
    Search in Google Scholar
  39. Berek L, Petri IB, Mesterháy A, Téen J, Molná J. Effects of mycotoxins on human immune functions in vitro. Toxicol In Vitro 2001;15:25-30.10.1016/S0887-2333(00)00055-2
    Search in Google Scholar
  40. Tammer B, Lehmann I, Nieber K, Altenburger R. Combined effects of mycotoxin mixtures on human T cell function. Toxicol Lett 2007;170:124-33.10.1016/j.toxlet.2007.02.01217400410
    Search in Google Scholar
DOI: https://doi.org/10.2478/10004-1254-60-2009-1973 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
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Language: English, Croatian, Slovenian
Page range: 411 - 418
Published on: Jan 7, 2010
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
histopathology,
immunotoxicity,
light microscopy,
morphometry,
mycotoxin,
cell Ultrastructure
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2010 Evrim Arzu Koçkaya, Güdeniz Selmanoğlu, Nesrin Özsoy, Nursel Gül, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 60 (2009): Issue 4 (December 2009)