Skip to main content
Have a personal or library account? Click to login
A Journey Through Mitogen-Activated Protein Kinase and Ochratoxin A Interactions Cover

A Journey Through Mitogen-Activated Protein Kinase and Ochratoxin A Interactions

Archives of Industrial Hygiene and Toxicology
Volume 60 (2009): Issue 4 (December 2009)
By:  and    
Open Access
|Jan 2010
References

References

  1. Clark HA, Snedeker SM. Ochratoxin A: its cancer risk and potential for exposure.2006;9:265-96.
    Open DOISearch in Google Scholar
  2. Miraglia M, Brera C, Pazzaglini B, Grossi S. Assessment of dietary intake of ochratoxin A by the population of EU member states. Directorate general health and consumer protection. Reports on tasks for scientific cooperation. Brussels: European Union; 2002.
    Search in Google Scholar
  3. Delacruz L, Bach PH. The role of ochratoxin A metabolism and biochemistry in animal and human nephrotoxicity.1990;1:277-304.
    Search in Google Scholar
  4. Gekle M, Sauvant C, Schwerdt G. Ochratoxin A at nanomolar concentrations: a signal modulator in renal cells.2005;49:118-30.
    Open DOISearch in Google Scholar
  5. Sauvant C, Holzinger H, Gekle M. The nephrotoxin ochratoxin A induces key parameters of chronic interstitial nephropathy in renal proximal tubular cells.2005;15:125-34.
    Open DOISearch in Google Scholar
  6. Kuiper-Goodman T, Scott PM. Risk assessment of the mycotoxin ochratoxin A.1989;2:179-248.
    Search in Google Scholar
  7. Studer-Rohr I, Schlatter J, Dietrich DR. Kinetic parameters and intraindividual fluctuations of ochratoxin A plasma levels in humans.2000;74:499-510.
    Open DOISearch in Google Scholar
  8. Stander MA, Nieuwoudt TW, Steyn PS, Shephard GS, Creppy EE, Sewram V. Toxicokinetics of ochratoxin A in vervet monkeys ().2001;75:262-9.
    Open DOISearch in Google Scholar
  9. Pfohl-Leszkowicz A, Manderville RA. Ochratoxin A: an overview on toxicity and carcinogenicity in animals and humans.2007;51:61-99.
    Open DOISearch in Google Scholar
  10. Dahlman A, Dantzler WH, Silbernagl S, Gekle M. Detailed mapping of ochratoxin A reabsorption along the rate nephron in vivo: the nephrotoxin can be reabsorbed in all nephron segments by different mechanisms.1998;286:157-62.
    Search in Google Scholar
  11. Pavlović M, Pleština R, Krogh P. Ochratoxin A contamination of foodstuffs in area with Balkan (endemic) nephropathy.1979;87:243-6.
    Open DOISearch in Google Scholar
  12. Pleština R, Čeović S, Gatenbeck S, Habazin-Novak V, Hult K, Hökby E, Krogh P, Radić B. Human exposure to ochratoxin A in areas of Yugoslavia with endemic nephropathy.1990;10:145-8.
    Search in Google Scholar
  13. Radovanovic Z, Jankovic S, Jevremovic I. Incidence of tumors of urinary organs in a focus of Balkan endemic nephropathy.1991;40(Suppl 34):S75-6.
    Search in Google Scholar
  14. Radić B, Fuchs R, Peraica M, Lucić A. Ochratoxin A in human sera in the area with endemic nephropathy in Croatia.1997;91:105-9.
    Open DOISearch in Google Scholar
  15. Simon P. Ochratoxin and kidney disease in the human.1996;15:239-49.]
    Open DOISearch in Google Scholar
  16. Bach PH, Morin JP, Pfaller W. Nephrotoxicity - what we have learned and what we still need to know!1996;3:4-13.
    Search in Google Scholar
  17. Schilter B, Marin-Kuan M, Delatour T, Nestler S, Mantle P, Cavin C. Ochratoxin A: potential epigenetic mechanisms of toxicity and carcinogenicity.2005;22(Suppl 1):88-93.
    Open DOISearch in Google Scholar
  18. O'Brien E, Dietrich DR. Ochratoxin A: the continuing enigma.2005;35:33-60.
    Open DOISearch in Google Scholar
  19. Ringot D, Chango A, Schneider YJ, Larondelle Y. Toxicokinetics and toxicodynamics of ochratoxin A, an update.2006;159:18-46.
    Open DOISearch in Google Scholar
  20. Petrik J, Žanić-Grubišić T, Barišić K, Pepeljnjak S, Radić B, Ferenčić Z, Čepelak I. Apoptosis and oxidative stress induced by ochratoxin A in rat kidney.2003;77:685-93.
    Open DOISearch in Google Scholar
  21. Mally A, Dekant W. DNA adduct formation by ochratoxin A: review of the available evidence.2005;22(Suppl 1):65-74.
    Open DOISearch in Google Scholar
  22. Rahimtula AD, Bèrèziat JC, Bussacchini-Griot V, Bartsch H. Lipid peroxidation as a possible cause of ochratoxin A toxicity.1988;37:4469-77.
    Open DOISearch in Google Scholar
  23. Schaaf GJ, Nijmeijer SM, Maas RF, Roestenberg P, de Groene EM, Fink-Gremmels J. The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells.2002;1588:149-58.
    Open DOISearch in Google Scholar
  24. Marin-Kuan M, Nestler S, Verguet C, Bezençon C, Piguet D, Delatour T, Mantle P, Cavin C, Schilter B. MAPK-ERK activation in kidney of male rats chronically fed ochratoxin A at a dose causing a significant incidence of renal carcinoma.2007;224:174-81.
    Open DOISearch in Google Scholar
  25. Horvath A, Upham BL, Ganev V, Trosko JE. Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line.2002;40:273-82.
    Open DOISearch in Google Scholar
  26. Gekle M, Schwerdt G, Freudinger R, Mildenberger S, Wilflingseder D, Pollack V, Dander M, Schramek H. Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations.2000;293:837-44.
    Search in Google Scholar
  27. Schwerdt G, Wilflingseder D, Pollack V, Freudinger R, Mildenberger S, Gekle M. Ochratoxin A-induced stimulation of extracellular signal-regulated kinases 1/2 is associated with Madin-Darby Canine Kidney-C7 cell dedifferentiation1997;283:1460-8.
    Search in Google Scholar
  28. Barišić K, Rumora L, Petrik J, Čepelak I, Žanić-Grubišić T. Ochratoxin A induces apoptosis in LLC-PK1 cells via JNK and p38 MAPK activation.2005;78:385-92.
    Search in Google Scholar
  29. Rumora L, Žanić Grubišić T. MAP kinase signalling cascades in cell proliferation and apoptosis. In: Markotić A, Glavaš-Obrovac Lj, Varljen J, Žanić-Grubišić T, editors. Biochemistry and immunology intersections. Kareala: Research Signpost; 2008. p. 151-71.
    Search in Google Scholar
  30. Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs.2007;26:3100-12.
    Open DOISearch in Google Scholar
  31. Krishna M, Narang H. The complexity of mitogen-activated protein kinases (MAPKs) made simple.2008;65:3525-44.
    Open DOISearch in Google Scholar
  32. Boutros T, Chevet E, Metrakos P. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer.2008;60:261-310.
    Open DOISearch in Google Scholar
  33. Dickinson RJ, Keyse SM. Diverse physiological functions for dual-specificity MAP kinase phosphatases.2006;119:4607-15.
    Open DOISearch in Google Scholar
  34. Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R, Westerhoff HV. Control of MAPK signalling: from complexity to what really matters.2005;24:5533-42.
    Open DOISearch in Google Scholar
  35. Hornberg JJ, Bruggeman FJ, Binder B, Geest CR, de Vaate AJ, Lankelma J, Heinrich R, Westerhoff HV. Principles behind the multifarious control of signal transduction. ERK phosphorylation and kinase/phosphatase control.2005;272:244-58.
    Open DOISearch in Google Scholar
  36. Rubinfeld H, Seger R. The ERK cascade: a prototype of MAPK signaling.2005;31:151-74.
    Open DOISearch in Google Scholar
  37. McKay MM, Morrison DK. Integrating signals from RTKs to ERK/MAPK.2007;26:3113-21.
    Open DOISearch in Google Scholar
  38. Whitmarsh AJ, Davis RJ. Transcription factor AP-1 regulation by mitogen-activated protein kinase signalling transduction pathways.1996;74:589-607.
    Open DOISearch in Google Scholar
  39. Shaul YD, Seger R. The MEK/ERK cascade: from signalling specificity to diverse functions.2007;1773:1213-26.
    Open DOISearch in Google Scholar
  40. Dong C, Davis RJ, Flavell RA. Signaling by the JNK group of MAP kinases. c-jun N-terminal Kinase.2001;21:253-7.
    Open DOISearch in Google Scholar
  41. Johnson GL, Nakamura K. The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.2007;1773:1341-8.
    Open DOISearch in Google Scholar
  42. Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation.1996;271:24313-6.
    Open DOISearch in Google Scholar
  43. Ashwell JD. The many paths to p38 mitogen-activated protein kinase activation in the immune system.2006;6:532-40.
    Open DOISearch in Google Scholar
  44. Sridhar SS, Hedley D, Siu LL. Raf kinase as a target for anticancer therapeutics.2005;4:677-85.
    Open DOISearch in Google Scholar
  45. Oka H, Chatani Y, Hoshino R, Ogawa O, Kakehi Y, Terachi T, Okada Y, Kawaichi M, Kohno M, Yoshida O. Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma.1995;55:4182-7.
    Search in Google Scholar
  46. Teng DH, Perry III WL, Hogan JK, Baumgard M, Bell R, Davis T, Frank D, Frye C, Hattier T, Hu R, Jammulapati S, Janecki T, Laevitt A, Mitvhell JT, Pero P, Sexton D, Schroeder M, Su PH, Swedlund B, Kyriakis JM, Avruch J, Bartel P, Wong AKC, Oliphant A, Thomas A, Skolnick MF, Tavtigian SV. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.1997;57:4177-82.
    Search in Google Scholar
  47. De Bruin EC, Medema JP. Apoptosis and non-apoptotic deaths in cancer development and treatment response.2008;34:737-49.
    Open DOISearch in Google Scholar
  48. Barišić K, Petrik J, Rumora L. Biochemistry of apoptotic cell death.2003;53:151-64.
    Search in Google Scholar
  49. Petrik J, Malić A, Barišić K, Rumora L, Kõszegi T, Pepeljnjak S, Žanić-Grubišić T, Čepelak I. Ochratoxin A induces apoptotic and necrotic renal cell death.2005;78:447-53.
    Search in Google Scholar
  50. Schwerdt G, Freudinger R, Mildenberger S, Silbernagl S, Gekle M. The nephrotoxin ochratoxin A induces apoptosis in cultured human proximal tubule cells.1999;15:405-15.
    Open DOISearch in Google Scholar
  51. Gekle M, Sauvant C, Schwerdt G, Silbernagl S. Tubulotoxic mechanisms of ochratoxin A.1998;21:277-9.
    Open DOISearch in Google Scholar
  52. Marin-Kuan M, Cavin C, Delatour T, Schilter B. Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms.2008;52:195-202.
    Open DOISearch in Google Scholar
  53. Sugiyama H, Kashihara N, Makino H, Yamasaki Y, Ota A. Apoptosis in glomerular sclerosis.1996;49:103-11.
    Open DOISearch in Google Scholar
  54. Thomas SE, Andoh TF, Pichler RH, Shankland SJ, Couser WG, Bennett WM, Johnson RJ. Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.1998;53:897-908.
    Open DOISearch in Google Scholar
  55. Woo D. Apoptosis and loss of renal tissue in polycystic kidney diseases.1995;333:18-25.
    Open DOISearch in Google Scholar
  56. Mantle PG, Milijkovic A, Udupa V, Dobrota M. Does apoptosis cause renal atrophy in Balkan endemic nephropathy?1998;352:1118-9.
    Open DOISearch in Google Scholar
  57. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis.1995;270:1326-31.
    Open DOISearch in Google Scholar
  58. Marshall CJ. Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signalregulated kinase activation.1995;80:179-85.
    Open DOISearch in Google Scholar
  59. Dikic I, Schlessinger J, Lax I. PC12 cells overexpression the insulin receptor undergo insulin-dependent neuronal differentiation.1994;4:702-8.
    Open DOISearch in Google Scholar
  60. Traverse S, Seedorf K, Paterson H, Marshall J, Cohen P, Ullrich A. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor.1994;4:694-701.
    Open DOISearch in Google Scholar
  61. Chen YR, Meyer CF, Tan TH. Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis.1996;271:631-4.
    Open DOISearch in Google Scholar
  62. Le-Niculescu H, Bonfoco E, Kasuya Y, Claret FX, Green DR, Karin M. Withdrawal of survival factors results in activation of the JNk pathway in neuronal cells leading to Fas ligand induction and cell death.1999;19:751-63.
    Open DOISearch in Google Scholar
  63. Xu X, Raber J, Yang D, Su B, Mucke L. Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli.1997;94:12655-60.
    Open DOISearch in Google Scholar
  64. Nagai H, Noguchi T, Takeda K, Ichijo H. Pathophysiological roles of ASK1-MAP kinase signalling pathways.2007;40:1-6.
    Search in Google Scholar
  65. Filomeni G, Rotilio G, Ciriolo MR. Disulfide relays and phosphorylative cascades: partners in redox-mediated signalling pathways.2005;12:1555-63.
    Open DOISearch in Google Scholar
  66. Sumbayev VV, Yasinska IM. Regulation of MAP kinasedependent apoptotic pathway: implication of reactive oxygen and nitrogen species.2005;436:406-12.
    Open DOISearch in Google Scholar
  67. Matsuzawa A, Ichijo H. Stress-responsive protein kinases in redox-regulated apoptosis signalling.2005;7:472-81.
    Open DOISearch in Google Scholar
  68. Klaunig JE, Kamendulis LM. The role of oxidative stress in carcinogenesis.2004;44:239-67.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/10004-1254-60-2009-1969 | Journal eISSN: 1848-6312 (formerly 0004-1254) | Journal ISSN: 0004-1254
Journal RSS Feed
Language: English, Croatian
Page range: 449 - 456
Published on: Jan 7, 2010
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Keywords:
apoptosis,
carcinogenicity,
kidney,
necrosis,
oxidative stress,
toxicity
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2010 Lada Rumora, Tihana Grubišić, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 60 (2009): Issue 4 (December 2009)
Previous article
Next article