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The Association of OGG1 Ser326Cys Polymorphism and Urinary 8-OHdG Levels With Lung Cancer Susceptibility: A Hospital-Based Case-Control Study in Turkey Cover

The Association of OGG1 Ser326Cys Polymorphism and Urinary 8-OHdG Levels With Lung Cancer Susceptibility: A Hospital-Based Case-Control Study in Turkey

Open Access
|Dec 2008

References

  1. Minna JD, Roth JA, Gazdar AF. Focus on lung cancer.2002;1:149-52.
  2. Howe HL, Wingo PA, Thun MJ, Ries LA, Rosenberg H, Feigal E, Edwards BK. Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends.2001;93:824-42.
  3. Bilello KS, Murin S, Matthay RA. Epidemiology, etiology, and prevention of lung cancer.2002;23:1-25.
  4. Turkish Ministry of Health. Cancer statistics according to years 1999 [displayed 28 April 2007] available at
  5. Littman AJ, Thornquist MD, White E, Jackson LA, Goodman GE, Vaughan TL. Prior lung disease and risk of lung cancer in a large prospective study.2004;15:819-27.
  6. Loft S, Poulsen HE. Cancer risk and oxidative DNA damage in man.1997;75:67-8.
  7. Eva Y, Lee HP. Tumor suppressor genes: a new era for molecular genetic studies of cancer.1991;19:3-13.
  8. Hoffmann H, Isner C, Högel J, Speit G. Genetic polymorphisms and the effect of cigarette smoking in the comet assay.2005;20:359-64.
  9. Karahalil B, Kocabas NA. OGG1 Ser326Cys genetic polymorphism in a Turkish population.2005;79:377-80.
  10. David SS. Structural biology: DNA search and rescue.2005;434:569-70.
  11. Kasai H. Analysis of a form of oxidative DNA damage 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis.1997;387:147-63.
  12. Karahalil B, Hogue BA, de Souza-Pinto NC, Bohr VA. Base excision repair capacity in mitochondria and nuclei: tissue-specific variations.2002;16:1895-902.
  13. Xing DY, Tan W, Song N, Lin DX. Ser326Cys polymorphism in OGG1 gene and risk of esophageal cancer in a Chinese population.2001;95:140-3.
  14. Kohno T, Shinmura K, Tosaka M, Tani M, Kim S, Sugimura H, Nohmi T, Kasai H, Yokota J. Genetic polymorphisms and alternative splicing of the OGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA.1998;16:3219-25.
  15. Vogel U, Olsen A, Wallin H, Overvad K, Tjonneland A, Nex BA. No Association between OGG1 Ser326Cys and Risk of Basal Cell Carcinoma.2004;13:1680-1.
  16. Xu J, Zheng SL, Turner A, Isaacs SD, Wiley KE, Hawkins GA, Chang BL, Bleeckeri ER, Walsh PC, Meyers DA, Isaacs WB. Associations between OGG1 sequence variants and prostate cancer susceptibility.2002;62:2253-7.
  17. Sugimura H, Kohno T, Wakai K, Nagura K, Genka K, Igarashi H, Morris BJ, Baba S, Ohno Y, Gao C, Li Z, Wang J, Takezaki T, Tajima K, Varga T, Sawaguchi T, Lum JK, Martinson JJ, Tsugane S, Iwamasa T, Shinmura K, Yokota J. OGG1 Ser326Cys polymorphism and lung cancer susceptibility.1999;8:669-74.
  18. Kohno T, Sakiyama T, Kunitoh H, Goto K, Nishiwaki Y, Saito D, Sasaki-Matsumura R, Mimaki S, Toyama K, Yamamoto S, Kuchiba A, Sobue T, Ohta T, Ohki M, Yokota J. Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk.2006;27:2448-54.
  19. Wikman H, Risch A, Klimek F, Schmezer P, Spiegelhalder B, Dienemann H, Kayser K, Schulz V, Drings P, Bartsch H. OGG1 polymorphism and loss of heterozygosity (LOH): Significance for lung cancer susceptibility in a caucasian population.2000;88:932-7.
  20. Lan Q, Mumford JL, Shen M, DeMarini DM, Bonner MR, He X, Yeager M, Welch R, Chanock S, Tian L, Chapman RS, Zheng T, Keohavong P, Caporaso N, Rothman N. Oxidative damage-related genes AKR1C3 and OGG1 modulate risks for lung cancer due to exposure to PAH-rich coal combustion emissions.2004;25:2177-81.
  21. Marchand LL, Donlon F, Lum-Jones A, Seifried A, Wilkens LR. Association of the OGG1 Ser326Cys polymorphism with lung cancer risk.2002;11:409-12.
  22. De Ruyck K, Szaumkessel M, De Rudder I, Dehoorne A, Vral A, Claes K, Velghe A, Van Meerbeeck J, Thierens H. Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.2007;631:101-10.
  23. Forgacs E, Zöchbauer-Müller S, Olah E, Minna JD. Molecular genetic abnormalities in the pathogenesis of human lung cancer.2001;7:6-13.
  24. Hussain SP, Haris CC. Molecular epidemiology of human cancer: Contribution of mutation spectra studies of tumor suppressor genes.1998;58:4023-37.
  25. Lu R, Nash HM, Verdine GL. A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer.1997;7:397-407.
  26. Karahalil B, Kocabas NA, Ozcelik T. DNA repair gene polymorphism and bladder cancer susceptibility in a Turkish population.2006;26:4955-8.
  27. Park J, Chen L, Tockman MS, Elahi A, Lazarus P. The human 8-oxoguanine DNA N-glycosylase 1 (OGG1) DNA repair enzyme and its association with lung cancer risk.2003;14:103-9.
  28. Zhang Y, Newcomb PA, Egan KM, Titus-Ernstoff L, Chanock S, Welch R, Brinton LA, Lissowska J, Bardin-Mikolajczak A, Peplonska B, Szeszenia-Dabrowska N, Zatonski W, Garcia-Closas M. Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer.2006;2:353-8.
  29. Nock NL, Cicek MS, Li L, Liu X, Rybicki BA, Moreira A, Plummer SJ, Casey G, Witte JS. Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk.2006;27:1842-8.
  30. Rossner P, Terry MB, Gammon MD, Zhang FF, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut AI, Santella RM. OGG1 Polymorphisms and breast cancer risk.2006;15:811-5.
  31. Smart DJ, Chipman JK, Hodges NJ. Activity of OGG1 variants in the repair of pro-oxidant-induced 8-oxo-2'-deoxyguanosine.2006;5:1337-45.
  32. Vodicka P, Stetina R, Polakova V, Tulupova E, Naccarati A, Vodickova L, Kumar R, Hanova M, Pardini B, Slyskova J, Musak L, De PG, Soucek P, Hemminki K. Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects.2006;28:657-64.
  33. Janssen K, Schlink K, Gotte W, Hippler B, Kaina B, Oesch F. DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.2001;486:207-16.
  34. Hung RJ, Hall J, Brennan P, Boffetta P. Genetic polymorphisms in the base excision repair pathway and cancer risk: a huge review.2005;162:925-42.
  35. Paz-Elizur T, Krupsky M, Blumenstein S, Elinger D, Schechtman E, Livneh Z. DNA repair activity for oxidative damage and risk of lung cancer.2003;95:1312-9.
  36. Hung RJ, Brennan P, Canzian F, Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mates D, Foretova L, Janout V, Bencko V, Chabrier A, Borel S, Hall J, Boffetta P. Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study.2005;97:567-76.
  37. Vogel U, Nexø BA, Wallin H, Overvad K, Tjønneland A, Raaschou-Nielsen O. No association between base excision repair gene polymorphisms and risk of lung cancer,2004;42:453-60.
  38. Sørensen M, Raaschou-Nielsen O, Hansen RD, Tjønneland A, Overvad K, Vogel U. Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer.2006;40:885-91.
  39. Ito H, Hamajima N, Takezaki T, Matsuo K, Tajima K, Hatooka S, Mitsudomi T, Suyama M, Sato S, Ueda RA. Limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung.2002;12:258-65.
  40. Loft S, Svoboda P, Kasai H, Tjønneland A, Vogel U, Moller P, Overvad K, Raaschou-Nielsen O. Prospective study of 8-oxo-7, 8-dihydro-20-deoxyguanosine excretion and the risk of lung cancer.2006;27:1245-50.
  41. Erhola M, Toyokuni S, Okada K, Tanaka T, Hiai H, Ochi H, Uchida K, Osawa T, Nieminen MM, Alho H, Kellokumpu-Lehtinen P. Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8-hydroxy-2'-deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment.1997;409:287-91.
DOI: https://doi.org/10.2478/10004-1254-59-2008-1924 | Journal eISSN: 1848-6312 (formerly 0004-1254) | Journal ISSN: 0004-1254
Language: English, Croatian, Slovenian
Page range: 241 - 250
Published on: Dec 8, 2008
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services

© 2008 Bensu Karahalil, Esra Emerce, Bülent Koçer, Serdar Han, Necati Alkiş, Ali Karakaya, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.