Skip to main content
Have a personal or library account? Click to login
T-2 Toxin: Incidence and Toxicity in Poultry Cover

T-2 Toxin: Incidence and Toxicity in Poultry

Archives of Industrial Hygiene and Toxicology
Volume 59 (2008): Issue 1 (March 2008)
By: ,   and    
Open Access
|Apr 2008
References

References

  1. Desjardins AE, Hohn TM, McCormick SP Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance.1993;57:595-604.
    Open DOISearch in Google Scholar
  2. Hsia CC, Wu JL, Lu XQ, Li YS. Natural occurrence and clastogenic effects of nivalenol, deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in corn from a high-risk area of esophageal cancer.1988;13:79-86.
    Search in Google Scholar
  3. Oldham JW, Allred LE, Milo GE, Kindig O, Capen CC. The toxicological evaluation of the mycotoxins T-2 and T-2 tetraol using normal human fibroblasts in vitro.1980;52:159-68.
    Open DOISearch in Google Scholar
  4. Jone C, Erickson L, Trosko JE, Chang CC. Effect of biological toxins on gap-junctional intercellular communication in Chinese hamster V79 cells.1987;3:1-15.
    Open DOISearch in Google Scholar
  5. Sun XM, Zhang XH, Wang HY, Cao WJ, Yan X, Zuo LF, Wang JL, Wang FR. Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro.2002;15:145-52.
    Search in Google Scholar
  6. Pestka JJ, Zhou HR, Moon Y, Chung YJ. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox.2004;153:61-73.
    Open DOISearch in Google Scholar
  7. Shinozuka J, Li G, Uetsuka K, Nakayama H, Doi K. Process of the development of T-2 toxin-induced apoptosis in the lymphoid organs of mice.1997;46:117-26.
    Open DOISearch in Google Scholar
  8. Islam Z, Nagase M, Ota A, Ueda S, Yoshizawa T, Sakato N. Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice.1998;62:1492-7.
    Open DOISearch in Google Scholar
  9. Murshedul AM, Nagase M, Yoshizawa T, Sakato N. Thymocyte Apoptosis by T-2 toxin in vivo in mice is independent of fas/fas ligand system.2000;64:210-3.
    Open DOISearch in Google Scholar
  10. Poapolathep A, Ohtsuka R, Kiatipattanasakul W, Ishigami N, Nakayama H, Doi K. Nivalenol-induced apoptosis in thymus, spleen and peyer's patches of mice.2002;53:441-6.
    Open DOISearch in Google Scholar
  11. Bondy GS, Pestka, JJ. Immunomodulation by fungal toxins.2000;3:109-43.
    Open DOISearch in Google Scholar
  12. Minervini F, Fornelli F, Lucivero G, Romano C, Visconti A. T-2 toxin immunotoxicity on human B and T lymphoid cell lines.2005;210:81-91.
    Open DOISearch in Google Scholar
  13. Jaradat ZW, Vila B, Marquardt RR. Adverse effects of T-2 toxin on chicken lymphocytes blastogenesis and its protection with Vitamin E.2006;225:90-6.
    Open DOISearch in Google Scholar
  14. Sharma RP. Immunotoxicity of Mycotoxins.1993;76:892-7.
    Open DOISearch in Google Scholar
  15. Wyatt RD, Hamilton PB, Burmeister HR. The effects of T-2 toxin in broiler chickens.1973;52:1853-9.
    Open DOISearch in Google Scholar
  16. Boonchuvit B, Hamilton PB, Burmeister HR. Interaction of T-2 toxin with Salmonella infections of chicken.1975;54:1693-6.
    Open DOISearch in Google Scholar
  17. Ziprin RL, Elissalde MH. Effect of T-2 toxin on resistance to systemic Salmonella typhimurium infection of newly hatched chickens.1990;51:1869-72.
    Search in Google Scholar
  18. Kamalavenkatesh P, Viaramuthu S, Balachandran C, Murali Manohar B, Dhinakar raj G. Immunopathological effect of the mycotoxins cyclopiazonic acid and T-2 toxin on broiler chicken.2005;159:273-9.
    Open DOISearch in Google Scholar
  19. Girish, CK, Devegowda, G. Efficacy of glucomannancontaining yeast product (Mycosorb®) and hydrated sodium calcium aluminosilicate in preventing the individual and combined toxicity of alfatoxin and T-2 toxin in commercial broilers.2006;19:877-83.
    Open DOISearch in Google Scholar
  20. Ademoyero AA, Hamilton PB. Mouth lesions in broiler chickens caused by scirpenol mycotoxins.1991;70:2082-9.
    Open DOISearch in Google Scholar
  21. Ademoyero AA, Hamilton PB. Influence of degree of acetylation of scirpenol mycotoxins on feed refusal by chickens.1989;68:854-6.
    Open DOISearch in Google Scholar
  22. Konjević D, Srebočan E, Gudan A, Lojkić I, Severin K, Sokolović M. A pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report.2004;33:377-80.
    Open DOISearch in Google Scholar
  23. Wyatt RD, Harris JR, Hamilton PB, Burmeister HR. Possible outbreaks of fusariotoxicosis in avians.1972;16:1123-30.
    Open DOISearch in Google Scholar
  24. Chi MS, Mirocha CJ. Necrotic oral lesions in chickens fed diacetoxyscirpenol, T-2 toxin and crotocin.1978;57:807-8.
    Open DOISearch in Google Scholar
  25. Brake J, Hamilton PB, Kittrell RS. Effects of the trichothecene mycotoxin diacetoxyscirpenol on feed consumption, body weight and oral lesions of broiler breeders.2000;79:856-63.
    Open DOISearch in Google Scholar
  26. Chi MS, Robison TS, Mirocha CJ, Swanson SP, Shimoda W. Excretion and tissue distribution of radioactivity from tritium-labeled T-2 toxin in chicks.1978;45:391-402.
    Open DOISearch in Google Scholar
  27. Yoshizawa T, Swanson SP, Mirocha CJ. T-2 metabolites in the excreta of broiler chickens administered 3H-labeled T-2 toxin.1980;39:1172-7.
    Open DOISearch in Google Scholar
  28. Prelusky DB, Hamilton RMG, Trenholm HL, Miller JD. Tissue distribution and excretion of radioactivity following administration ofC-labeled deoxynivalenol to White Leghorn hens.1986;7:635-45.
    Open DOISearch in Google Scholar
  29. Young JC, Zhou T, Yu H, Zhu H, Gong J. Degradation of trichothecene mycotoxins by chicken intestinal microbes.2007;45:136-43.
    Open DOISearch in Google Scholar
  30. Smith TK. Recent Advances in the Understanding of Fusarium trichothecene mycotoxicoses.1992;70:3989-93.
    Open DOISearch in Google Scholar
  31. Wang J, Fitzpatrick DW, Wilson JR Effects of T-2 toxin on blood-brain barrier permeability monamine oxidase activity and protein synthesis in rats.1998;36:955-61.
    Open DOISearch in Google Scholar
  32. Wyatt RD, Colwell WM, Hamilton PB, Burmeister HR. Neural disturbances in chickens caused by dietary T-2 toxin.1973;26:757-61.
    Open DOISearch in Google Scholar
  33. Wyatt RD, Hamilton PB, Burmeister HR. Altered feathering of chicks caused by T-2 toxin.1975;54:1042-45.
    Open DOISearch in Google Scholar
  34. Chi MS, Mirocha CJ, Kurtz HF, Weaver G, Bates F, Shimoda W. Effects of T-2 toxin on reproductive performance and health of laying hens.1977;56:628-37.
    Open DOISearch in Google Scholar
  35. Tobias S, Rajic I, Vanyi A. Effect of T-2 toxin on egg production and hatchability in laying hens.1992;40:47-54.
    Search in Google Scholar
  36. Pier AC, Richard JL, Cysewski SJ. The implications of mycotoxins in animal disease.1980;176:719-24.
    Search in Google Scholar
  37. Food and Agriculture Organization (FAO). Report of the 33Session of the Codex Committee on Food Additives and Contaminants, 2001 [displayed 23 November 2007]. Available at
    Search in Google Scholar
  38. European Commission (EC). Commission recommendation of 17 August 2006 on the presence of deoxynivalenol, zearalenone, ochratoxin A, T-2 and HT-2 and fumonisins in products intended for animal feeding No 576, 2006 [displayed 23 November 2007]. Available at
    Search in Google Scholar
  39. Know Mycotoxins. Regulations [displayed 23 November 2007]. Available at
    Search in Google Scholar
  40. Pravilnik o nepoželjnim i zabranjenim tvarima u hrani za životinje [Act on undesirable and forbidden substances in animal feed, in Croatian]. Narodne Novine 118/2007.
    Search in Google Scholar
  41. Beaver RW. Decontamination of mycotoxin-containing foods and feedstuffs.1991;2:170-3.
    Open DOISearch in Google Scholar
  42. Peraica M, Domijan A, Jurjević Ž, Cvjetković B. Prevention of exposure to mycotoxins form food and feed.2002;53:229-37.
    Search in Google Scholar
  43. Diaz GJ, Cortes A, Roldan L. Evaluation of the efficacy of four feed additives against the adverse effects of T-2 toxin in growing broiler chickens.2005;14:226-31.
    Open DOISearch in Google Scholar
  44. Eriksen GS, Pettersson H. Toxicological evaluation of trichothecenes in animal feed.2004;114:205-39.
    Open DOISearch in Google Scholar
  45. Brlek V, Pavičić P, Vedrina J. Prisutnost fuzarijskih plijesni i nekih njihovih mikotoksina u žitaricama namijenjenih hranidbi životinja.1999;41:195-9.
    Search in Google Scholar
  46. Pavičić P, Brlek V, Nemanič A. Učestalost fuzarijskih mikotoksina u krmnim smjesama: 1989-1998.1999;41:183-8.
    Search in Google Scholar
  47. Pepeljnjak S, Šegvić M. An Overview of mycotoxins and toxigenic fungi in Croatia. In: Logrieco A, Visconti A, editors. An Overview on Toxigenic Fung and Mycotoxins in Europe. Dordrecht: Kluwer Academic Publishers; 2004. p. 33-50.
    Open DOISearch in Google Scholar
  48. Sokolović M, Šimpraga B. Survey of trichothecene mycotoxins in grains and animal feed in Croatia by thin layer chromatography.2006;17:733-40.
    Open DOISearch in Google Scholar
  49. Joint Expert Committee on Food Additives (JECFA). T-2 and HT-2 toxins. Monographs & Evaluations No. 47, 2001 [displayed 23 November 2007]. Available at
    Search in Google Scholar
  50. World Health Organization (WHO). Selected Mycotoxins: Ochratoxin, Trichothecenes, Ergot. Environmental Health Criteria 105, 1990 [displayed 23 November 2007]. Available at
    Search in Google Scholar
  51. World Health Organization (WHO). Evaluation of certain mycotoxins in food. WHO Techn Rep Ser 906. Geneva: WHO; 2002.
    Search in Google Scholar
  52. Meek IB, Peplow AW, Ake C, Phillips TD, Beremand MN. Tri1 encodes the cytochrome P450 monooxygenase for C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporotrichioides and resides upstream of another new tri gene.2003;69:1607-13.
    Open DOISearch in Google Scholar
  53. Ožegović L, Pepeljnjak S Mikotoksikoze. Zagreb: Školska knjiga; 1995.
    Search in Google Scholar
  54. Hoerr FJ, Carlton WW, Yagen B, Joffe AZ. Mycotoxicosis caused by either T-2 toxin or diacetoxyscirpenol in the diet of broiler chickens.1982;2:121-4.
    Open DOISearch in Google Scholar
  55. Beasley VR, Swanson SP, Corley RA, Buck WB, Koritz GD, Burmeister HR. Pharmacokinetics of the trichothecene mycotoxin, T-2 toxin, in swine and cattle.1986;24:13-23.
    Open DOISearch in Google Scholar
  56. International Agency for Research on Cancer (IARC). Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic Amines and Mycotoxins. Lyon: IARC Press; 1993.
    Search in Google Scholar
  57. Rotter B, Prelusky DB, Petska JJ. Toxicology of deoxynivalenol (vomitoxin).1996;48:1-34.
    Open DOISearch in Google Scholar
  58. Kiessling KH. Biochemical mechanism of action of mycotoxins.1986;58:327-38.
    Open DOISearch in Google Scholar
  59. Ueno Y, Umemori K, Niimi EC, Tanuma S, Nagata SI, Sugamata M, Ihara T, Sekijima M, Kawai KI, Ueno I. Induction of apoptosis by T-2 toxin and other natural toxins in HL-60 human promyelotic leukemia cells.1995;3:129-37.
    Open DOISearch in Google Scholar
  60. Hoerr FJ. Mycotoxicoses. In: Saif YM, editor. Diseases of Poultry. 11ed. Ames, Iowa, USA: Iowa State University Press; 2003. p. 1103-32.
    Search in Google Scholar
  61. Smith KE, Cannon M, Cundliffe E. Inhibition at the initiation level of eukaryotic protein synthesis by T-2 toxin.1975;50:8-12.
    Open DOISearch in Google Scholar
  62. Cundliffe E, Davies JE. Inhibition of initiation, elongation, and termination of eukaryotic protein synthesis by trichothecene fungal toxins.1977;11:491-9.
    Open DOISearch in Google Scholar
  63. Jimenez A, Vazquez D. Quantitative binding of antibiotics to ribosomes from a yeast mutant altered on the peptidyl-transferase center.1975;54:483-92.
    Open DOISearch in Google Scholar
  64. Lafarge-Frayssinet C, Decloitre F, Mousset S, Martin M, Frayssinet C. Induction of DNA single strand breaks by T2 toxin, a trichothecene metabolite of Fusarium, effect on lymphoid organs and liver.1981;88:115-23.
    Open DOISearch in Google Scholar
  65. Venkatesh PK, Vairamuthu S, Balachandran C, Manohar BM, Raj GD. Induction of apoptosis by fungal culture materials containing cyclopiazonic acid and T-2 toxin in primary lymphoid organs of broiler chickens.2005;159:393-400.
    Open DOISearch in Google Scholar
  66. Wei CM, Hansen BS, Vaughan MH, McLaughlin CS. Mechanism of action of the mycotoxin trichodermin, a 12-13-epoxytrichothecene.1974;71:713-17.
    Open DOISearch in Google Scholar
  67. Corrier DE. Mycotoxicosis: mechanisms of immunosuppression.1991;30:73-87.
    Open DOISearch in Google Scholar
  68. Linnainmaa K, Sorsa M, Ilus T. Epoxytrichothecene mycotoxins as c-mitotic agents in Allium.1979;90:151-6.
    Open DOISearch in Google Scholar
  69. Sorsa M, Linssainmaa K, Paittela M, Ilus T. Evaluation of the mutagenicity of epoxytrichothecene mycotoxins in Drosophila melanogaster.1980;92:163-5.
    Open DOISearch in Google Scholar
  70. Norppa H, Penttila M, Sorsa M, Hintikka EL, Ilus T. Mycotoxin T-2 of Fusarium tricinctum and chromosome changes in Chinese hamster bone marrow.1980;93:329-32.
    Open DOISearch in Google Scholar
  71. Thust R, Kneist S, Huehne V. Genotoxicity of Fusarium mycotoxins (nivalenol, fusarenon-X, T-2 toxin and zearalenone) in Chinese hamster V79-E cells in vitro.1983;53:9-15.
    Search in Google Scholar
  72. Hsia CC, Gao Y, Wu JL, Tzian BL. Induction of chromosome aberrations by Fusarium T-2 toxin in cultured human peripheral blood lymphocytes and Chinese hamster fibroblasts.1986;129:65-72.
    Open DOISearch in Google Scholar
  73. Zhu GF, Cheng SJ, Li MH. The genotoxic effects of T-2 toxin, a trichothecene produced by Fusarium fungi.1987;20:129-34.
    Search in Google Scholar
  74. European Commission (EC). Opinion of the Scientific Committee on Food on Fusarium-toxins Part 5: T-2 toxin and HT-2 toxin, 2001 [displayed 23 November 2007] Available at
    Search in Google Scholar
  75. European Commission (EC). Reports on tasks for scientific co-operation. Collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU Member States, 2001 [displayed 23 November 2007]. Available at
    Search in Google Scholar
  76. Krska R, Baumgartner S, Josephs R. The state-of-the-art in the analysis of type-A and type-B tricothecene mycotoxins in cereals.2001;371:285-99.
    Open DOISearch in Google Scholar
  77. Rocha O, Ansari K, Doohan FM Effects of trichothecene mycotoxins on eukaryotic cells: a review.2005;22:369-78.
    Open DOISearch in Google Scholar
  78. Zöllner P, Mayer-Helm B. Trace mycotoxins analysis in complex biological and food matrices by liquid chromatography-atmospheric pressure ionisation mass spectrometry.2006;1136:123-69.
    Open DOISearch in Google Scholar
  79. Ueno Y. Trichothecenes: overview address. In: Rodricks JV, Hesseltine DW, Mehlman MA, editors. Mycotoxins in Human and Animal Health. Park Forest South, Illinois, USA: Pathotox Publishers; 1977. p. 189-207.
    Search in Google Scholar
  80. Leeson S, Diaz G, Summers JD Poultry Metabolic Disorders and Mycotoxins. Ontario, Canada: University Books; 1995.
    Search in Google Scholar
  81. Burmeister HR, Ellis JJ, Yates SG Correlation of biological to chromatographic data for two mycotoxins elaborated by Fusarium.1971;21:673-5.
    Open DOISearch in Google Scholar
  82. Desjardins AE, Plattner RD, Vandmiddlesworth F Trichothecene biosynthesis in Fusarium sporotrichioides: origin of the oxygen atoms of T-2 Toxin.1986;51:493-7.
    Open DOISearch in Google Scholar
  83. Wannemacher RW, Wiener SL. Trichothecene mycotoxins. In: Zajtchuk R, editor. Textbook Of Military Medicine. Washington DD, USA: Walter Reed Army Medical Center; 1997. p. 655-76.
    Search in Google Scholar
  84. Bottalico A, Perrone G. Toxigenic Fusarium species and mycotoxins associated with head blight in small-grain cereals in Europe.2002;108:611-24.
    Open DOISearch in Google Scholar
  85. Moss MO. Mycotoxin review - 2. Fusarium.2002;16:158-61.
    Search in Google Scholar
  86. Kosiak B, Torp N, Skjerve E, Thrane U The Prevalence and distribution ofspecies in Norwegian cereals: a survey.2003;53:168-76.
    Open DOISearch in Google Scholar
  87. Betina V. Mycotoxins, Production, Isolation, Separation and Purification. Amsterdam: Elsevier Science Publishers BV; 1984.
    Search in Google Scholar
  88. Shepard MJ, Gilbert J. Long-Term storage stability of deoxynivalenol standard reference solutions.1988;36:305-8.
    Open DOISearch in Google Scholar
  89. Beeton S, Bull AT. Biotransformation and detoxification of T-2 Toxin by soil and freshwater bacteria.1989;55:190-7.
    Open DOISearch in Google Scholar
  90. Jesenska Z, Sajbidorova J. T-2 toxin degradation by micromycetes.1991;35:41-9.
    Search in Google Scholar
  91. Mateo JJ, Mateo R, Jimenez M. Accumulation of type A trichothecenes in maize, wheat and rice by Fusarium sporotrichiides isolates under diverse culture conditions.2002;72:115-23.
    Open DOISearch in Google Scholar
  92. Rasmussen PH, Ghorbani F, Berg T. Deoxynivalenol and othertoxins in wheat and rye flours on the Danish market.2003;20:396-404.
    Open DOISearch in Google Scholar
  93. Bergers WWA, van der Stap JGMM, Kientz CE. Trichothecene production in liquid stationary cultures of Fusarium tricinctum NRRL 3299 (Synonym:comparison of quantitative brine shrimp assay with physicochemical analysis.1985;50:656-62.
    Open DOISearch in Google Scholar
  94. D'Mello JPF, Placinta CM, Macdonald AMC. Fusarium mycotoxins: a review of global implications for animal health, welfare and productivity.1999;80:183-205.
    Open DOISearch in Google Scholar
  95. Homdork S, Fehrmann H, Beck R. Influence of different storage conditions on the mycotoxin production and quality of Fusarium-infected wheat grain.2000;148:7-15.
    Open DOISearch in Google Scholar
  96. Cullen D, Smalley EB, Caldwell RW. New process for T-2 toxin production.1982;44:371-5.
    Open DOISearch in Google Scholar
  97. Park JJ, Chu FS. Immunochemical analysis of trichothecenes produced by various fusaria.1993;121:179-92.
    Open DOISearch in Google Scholar
  98. Park JJ, Smalley EB, Chu FS. Natural occurrence of Fusarium mycotoxins in field samples from the 1992 Wisconsin corn crop.1996;62:1642-8.
    Open DOISearch in Google Scholar
  99. Murphy PA, Hendrich S, Landgren C, Bryant CM. Food mycotoxins: an update.2006;71:R51-65.
    Open DOISearch in Google Scholar
  100. Gareis M, Bauer J, Enders C, Gedek B. Contamination of cereals and feed with Fusarium mycotoxins in European countries. In: Chelkowski J, editor.mycotoxins, taxonomy and pathogenicity. Vol. 2. Amsterdam: Elsevier Science Publishers BV; 1989. p. 441-72.
    Open DOISearch in Google Scholar
  101. Langseth W, Rundberget T. The occurrence of HT-2 toxin and other trichothecenes in Norwegian cereals.1999;147:157-65.
    Open DOISearch in Google Scholar
  102. Schollenberger M, Müller HM, Rüfle M, Suchy S, Plank S, Drochner W Natural occurence of 16 Fusarium toxins in grains and feedstuffs of plant origin from germany.2006;161:43-52.
    Open DOISearch in Google Scholar
  103. Kawamura O, Satoshi N, Sonomi S, Ohtani K, Yoshitugu S, Tanaka T, Ueno Y. Survey of T-2 toxin in cereals by an indirect enzyme linked immunosorbent assay.1990;2:173-80.
    Open DOISearch in Google Scholar
  104. Perkowski J, Basinski T. Natural contamination of oat with group A trichotecenes mycotoxins in Poland.2002;19:478-82.
    Open DOISearch in Google Scholar
  105. Haubruge E, Chasseur C, Suetens C, Mathieu F, Begaux F, Malaisse F. Mycotoxins in stored barley () in Tibet Autonomous Region (People's Republic of China).2003;23:284-7.
    Open DOISearch in Google Scholar
  106. Beker D. Prisutnost T-2 toksina i diacetoksiscirpenola u krmivima i smjesama za perad.1988;58:133-7.
    Search in Google Scholar
  107. Sudakin DL. Trichothecenes in the environment: relevance to human health.2003;143:97-107.
    Open DOISearch in Google Scholar
  108. Cundliffe E, Cannon M, Davies J Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins.1974;71:30-4.
    Open DOISearch in Google Scholar
  109. Bilgrami KS, Masood A, Rahman MF. Cumulative effect of T-2 toxin and vitamin C on chromosomal abnormalities in the bone marrow cells of mice (Mus musculus).1995;81:171-4.
    Search in Google Scholar
  110. Sokolovic M, Garaj-Vrhovac V, Ramic S, Simpraga B. Chicken nucleated blood cells as a cellular model for genotoxicity testing using the comet assay.2007;45:2165-70.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/10004-1254-59-2008-1843 | Journal eISSN: 1848-6312 (formerly 0004-1254) | Journal ISSN: 0004-1254
Journal RSS Feed
Language: English, Croatian
Page range: 43 - 52
Published on: Apr 11, 2008
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Keywords:
cytotoxicity,
genotoxicity,
trichothecene mycotoxins
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2008 Marijana Sokolović, Verica Garaj-Vrhovac, Borka ŠImpraga, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 59 (2008): Issue 1 (March 2008)
Previous article
Next article