References
- 1. Newman DJ, Cragg GM. Natural Products as Sources of New Drugs from 1981 to 2014. J Nat Prod 2016; 79(3): 629-661.
- 2. De Sa Ferreira IC, Ferraro Vargas VM. Mutagenicity of medicinal plant extracts in Salmonella/microsome assay. Phytother Res 1998; 13(5): 397-400.
- 3. Celik TA, Aslanturk OS. Cytotoxic and genotoxic effects of Lavandula stoechas aqueous extracts. Biologia 2007; 62(3): 292-296.
- 4. Foster S, Duke JA. Eastern/Central Medicinal Plants and Herbs. Houghton Miflin Company, Boston 2000; 411.
- 5. Tita B, Abdel-Haq H, Vitalone A, Mazzanti G, Saso L. Analgesic properties of Epilobium angustifolium, evaluated by the hot plate test and the writhing test. Farmaco 2001; 56(5-7): 341-343.
- 6. Juan H, Sametz W, Hiermann A. Anti-inflammatory effects of a substance extracted from Epilobium angustifolium. Agents Actions 1988; 23(1-2): 106-107.10.1007/BF01967206
- 7. Hiermann A, Reidlinger M, Juan H, Sametz W. Isolation of the antiphlogistic principle from Epilobium angustifolium. Planta Med 1991;57(4): 357-360.10.1055/s-2006-960117
- 8. Vitalone A, Bordi F, Baldazzi C, Mazzanti G, Saso L, Tita B. Antiproliferative effect on a prostatic epithelial cell line (PZ-HPV-7) by Epilobium angustifolium L. Farmaco 2001; 56 (5-7): 483-489.
- 9. Vitalone A, Guizzetti M, Costa LG, Tita B. Extracts of various species of Epilobium inhibit proliferation of human prostate cells. J Pharm Pharmacol 2003; 55(5): 683-690.10.1211/002235703765344603
- 10. Stolarczyk M, Naruszewicz M, Kiss AK. Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating the mitochondrial pathway. J Pharm Pharmacol 2013; 65(7): 1044-1054.
- 11. Chuyeshov V, Hohlova L, Lyapunova O. Industrial technology of drugs. Kharkiv: Golden Pages 2003; 720.
- 12. Rashidinejad A, Birch EJ, Sun Waterhouse D, Everet DW. Effects of catechin on the phenolic content and antioxidant properties of low-fat cheese. Int J Food Sci Tech 2013; 48: 2448-2455.10.1111/ijfs.12234
- 13. Branciari R, Ranucci R, Trabalza-Marinucci M, Codini M, Orru M, Ortenzi R, Forte C, Ceccarini MR, Valiani A. Evaluation of the antioxidant properties and oxidative stability of Pecorino cheese made from the raw milk of ewes fed Rosmarinus officinalis L. leaves. Int J Food Sci Tech 2015; 50: 558-565.
- 14. Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch- Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORACFL) of plasma and other biological and food samples. J Agr Food Chem 2003; 51(11): 3273-3279.
- 15. Zulueta A, Maurizi A, Frigola A, Esteve MJ, Coli R, Burini G. Antioxidant capacity of cow milk, whey and deproteinized milk. Int Dairy J 2009; 19: 380-385.10.1016/j.idairyj.2009.02.003
- 16. Ceccarini MR, Vannini S, Cataldi S, Moretti M, Villarini M, Fioretti B, Albi E, Beccari T, Codini M. In Vitro Protective Effects of Lycium barbarum Berries Cultivated in Umbria (Italy) on Human Hepatocellular Carcinoma Cells. Biomed Res Int. 2016; 2016:7529521.
- 17. Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 1986; 89 (2): 271-277.
- 18. Ceccarini MR, Codini M, Cataldi S, Vannini S, Lazzarini A, Floridi A, Moretti M, Villarini M, Fioretti B, Beccari T, Albi E. Acid sphingomyelinase as target of Lycium Chinense: promising new action for cell health. Lipids Health Dis. 2016;15(1): 183.10.1186/s12944-016-0351-z
- 19. Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. Single cell gel/ comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen. 2000; 35(3): 206-221.10.1002/(SICI)1098-2280(2000)35:3<;206::AID-EM8>3.0.CO;2-J
- 20. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 1988; 175(1): 184-191.
- 21. Moretti M, Marcarelli M, Villarini M, Fatigoni C, Scassellati-Sforzolini G, Pasquini R. In vitro testing for genotoxicity of the herbicide terbutryn: cytogenetic and primary DNA damage. Toxicol In Vitro. 2002; 16(1):81-88.10.1016/S0887-2333(01)00092-3
- 22. Dominici L, Moretti M, Villarini M, Vannini S, Cenci G, Zampino C, Traina G. In vivo antigenotoxic properties of a commercial probiotic supplement containing bifidobacteria. Int J Probiotics and Prebiotics 2011; 6 (3-4): 179-186.
- 23. Collins A R. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol. 2004; 26(3): 249-261.10.1385/MB:26:3:249
- 24. Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997; 411(1): 77-82.
- 25. Villarini M, Pagiotti R, Dominici L, Fatigoni C, Vannini S, Levorato S, Moretti M. Investigation of the cytotoxic, genotoxic, and apoptosis-inducing effects of estragole isolated from fennel (Foeniculum vulgare). J Nat Prod. 2014; 77(4):773-778.
- 26. Nagata S. Apoptotic DNA fragmentation. Exp Cell Res 2000; 256(1): 12-18.
- 27. Nagata S, Nagase H, Kawane K, Mukae N, Fukuyama H. Degradation of chromosomal DNA during apoptosis. Cell Death Differ 2003; 10(1): 108-116.10.1038/sj.cdd.4401161
- 28. Kajstura M, Halicka HD, Pryjma J, Darzynkiewicz Z. Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete „sub-G1“ peaks on DNA content histograms. Cytometry A 2007; 71(3): 125-131.
- 29. Schepetkin IA, Ramstead AG, Kirpotina LN, Voyich JM, Jutila MA, Quinn MT. Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). Phytother Res 2016; 30(8): 1287-1297.
- 30. Kiss AK, Bazylko A, Filipek A, Granica S, Jaszewska E, Kiarszys U, Kośmider A, Piwowarski J. Oenothein B’s contribution to the anti-inflammatory and antioxidant activity of Epilobium sp. Phytomedicine 2011; 18(7): 557-560.10.1016/j.phymed.2010.10.016
- 31. Kiss A, Kowalski J, Melzig MF. Effect of Epilobium angustifolium L. extracts and polyphenols on cell proliferation and neutral endopeptidase activity in selected cell lines. Pharmazie 2006; 61(1): 66-69.
- 32. Kiss A, Kowalski J, Melzig MF. Compounds from Epilobium angustifolium inhibit the specific metallopeptidases ACE, NEP and APN. Planta Med 2004; 70(10): 919-923.
- 33. Kiss A, Kowalski J, Melzig MF. Induction of neutral endopeptidase activity in PC-3 cells by an aqueous extract of Epilobium angustifolium L. and oenothein B. Phytomedicine 2006; 13(4): 284-289.10.1016/j.phymed.2004.08.002
- 34. Dehn PF, White CM, Conners DE, Shipkey G, Cumbo TA. Characterization of the human hepatocellular carcinoma (HepG2) cell line as an in vitro model for cadmium toxicity studies. In Vitro Cell Dev Biol Anim 2004; 40(5-6): 172-182.
- 35. Xia JF, Gao JJ, Inagaki Y, Kokudo N, Nakata M, Tang W. Flavonoids as potential anti-hepatocellular carcinoma agents: recent approaches using HepG2 cell line. Drug Discov Ther 2013; 7(1): 1-8.