Recommendations of the Polish Society of Epileptology for the treatment of epileptic seizure in adult patients in Poland: an update

Jędrzejczak, Joanna; Majkowska-Zwolińska, Beata; Ryglewicz, Danuta; Nagańska, Ewa; Mazurkiewicz-Bełdzińska, Maria

doi:10.21307/joepi-2019-002

Abstract

Introduction

In 2014, a group of Polish epilepsy experts published recommendations for antiepileptic drug (AED) use in adults with epilepsy. Selection of AEDs was based on the registration and reimbursement status in Poland, evidence of efficacy, and the personal views and experiences of the epilepsy practitioners.

Method

In 2018 previous recommendations were reviewed by the ad hoc group consisting of the authors of the original paper and additional epilepsy experts. As a result of joint work and reaching a consensus, an updated version of these recommendations has been prepared.

Discussion and recommendations

This update focuses on the epileptic seizure type treatment recommendations for initial monotherapy and add-on treatment in adult patients. Some new relevant aspects of treatment with AEDs are addressed, including information on the safety of valproic acid (VPA) in women of childbearing potential.

References

Berg A.T., Shinnar S.: The risk of seizure recurrence following a first unprovoked seizure: a quantitative review. Neurology, 1991, 41: 965–972.
Search in Google Scholar Back to article
Bromley R.L., Mawer G., Love J., Kelly J., Purdy L., McEwan L., Liverpool and Manchester Neurodevelopment Group [LMNDG].: Early cognitive development in children born to women with epilepsy: a prospective report. Epilepsia, 2010, 51: 2058–2065. doi: 10.1111/j.1528-1167.2010.02668.x.
Open DOI Search in Google Scholar Back to article
Chen Z., Brodie M., Liew D., Kwan P.: Treatment outcomes in patients with newly diagnosed epilepsy treated with established antiepileptic drugs: a 30-year longitudinal cohort study. JAMA Neurol., 2018, 75: 279–286.
Search in Google Scholar Back to article
Commission on Classification and Terminology of the International League Against Epilepsy: Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia, 1981, 22: 489–501.
Search in Google Scholar Back to article
De Boer H., Mula M., Sander J.W.: The global burden and stigma of epilepsy. Epilepsy Behav., 2008, 12: 540–546.
Search in Google Scholar Back to article
Devinsky O., Cross J.H., Laux L., Marsh E., Miller I., Nabbout R., et al.: Trial of cannabidiol for drug-resistant seizures in the Dravet Syndrome. N. Engl. J. Med., 2017, 376: 2011–2020. doi: 10.1056/NEJMoa1611618.
Open DOI Search in Google Scholar Back to article
European Medicines Agency: New measures to avoid valproate exposure in pregnancy. EMA/145600/2018. https://www.ema.europa.eu/documents/preelease/new-measures-avoid-valproate-exposure-pregnancy-endorsed_en.
Search in Google Scholar Back to article
Fisher R.S., van Emde Boas W., Blume W., Elger C., Genton P., Lee P., Engel J. Jr.: Epileptic seizure and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia, 2005, 46: 470–472.
Search in Google Scholar Back to article
Fisher R.S., Acevedo C., Arzimanoglou A., Bogacz A., Cross J.H., Elger C.E. et al.: ILAE oficial report: a practical clinical definition of epilepsy. Epilepsia, 2014, 55: 475–482.
Search in Google Scholar Back to article
Fisher R.S., Cross J.H., French J.A., Higurashi N., Hirsch E., Jansen F.E. et al.: Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia, 2017a, 58: 522–530. doi: 10.1111/epi.13670
Open DOI Search in Google Scholar Back to article
Fisher R.S., Cross J.H., D’Souza C., French J.A., Haut S.R., Higurashi N. et al.: Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia, 2017b, 58: 531–542. doi: 10.1111/epi.13671.
Open DOI Search in Google Scholar Back to article
French J.A., Kanner A.M., Bautista J., Abou-Khalil B., Browne T., Harden C.L. et al.: Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia, 2004a, 45: 401–409.
Search in Google Scholar Back to article
French J.A., Kanner A.M., Bautista J., Abou-Khalil B., Browne T., Harden C.L. et al.: Efficacy and tolerability of the new antiepileptic drugs, II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology, 2004b, 62: 1261–1273.
Search in Google Scholar Back to article
Glauser T., Ben-Menachem E., Bourgeois B., Cnaan A., Chadwick D., Guerreiro C. et al.: ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia, 2006, 47: 1094–1120.
Search in Google Scholar Back to article
Harden C.L., Maroof A., Nikolov B., Fowler K., Sperling M., Liporace J. et al.: The effect of seizure severity on quality of life in epilepsy. Epilepsy Behav., 2007, 11: 208–211. doi. org/10.1016/j.yebeh.2007.05.002.
Search in Google Scholar Back to article
Hauser W.A., Rich S.S., Lee J.R., Annegers J.F., Anderson V.E.: Risk of recurrent seizures after two unprovoked seizures. N. Engl. J. Med., 1998, 338: 429–434.
Search in Google Scholar Back to article
Hesdorffer D.C., Benn E.K., Cascino G.D., Hauser W.A.: Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure. Epilepsia, 2009, 50: 1102–1108.
Search in Google Scholar Back to article
Jędrzejczak J., Majkowska-Zwolińska B., Ryglewicz D.: Zalecenia Polskiego Towarzystwa Epileptologii dotyczące leczenia napadów padaczkowych u dorosłych. Journal of Epileptology, 2014, 22 (Suppl. 2): 3–11.
Search in Google Scholar Back to article
Kanner A.M., Ashman E., Gloss D., Harden C., Bourgeois B., Bautista J.F. et al.: Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs II: Treatment-resistant epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology, 2018a, 91: 82–90. doi: 10.1212/WNL.0000000000005756.
Open DOI Search in Google Scholar Back to article
Kanner A.M., Ashman E., Gloss D., Harden C., Bourgeois B., Bautista J.F. et al.: Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs II: Treatment-resistant epilepsy: Report of the American Epilepsy Society and the Guideline. Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Epilepsy Curr., 2018b, 18: 269–278. doi: 10.5698/1535-7597.18.4.269.
Open DOI Search in Google Scholar Back to article
Majkowska-Zwolińska B., Majkowski J., Kaciński M., Kaczyńska-Haładyj M.: Przewlekłe schorzenia współwystępujące u osób z padaczką. Epileptologia, 2008, 16: 5–25.
Search in Google Scholar Back to article
Majkowska-Zwolińska B., Jędrzejczak J., Majkowski J.: Clinical use of concommitant medicines in epileptic patients in Poland: a 12 month prospective multicentre study. Seizure, 2011, 20: 673–678.
Search in Google Scholar Back to article
Meador K.J., Baker G.A., Browning N., Clayton-Smith J., Combs-Cantrell D.T., Cohen M. and NEAD Study Group: Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N. Engl. J. Med., 2009, 360: 1597–1605. doi: 10.1056/NEJMoa0803531.
Open DOI Search in Google Scholar Back to article
Mula M., Cock H.R.: More than seizures: improving the lives of people with refractory epilepsy. Eur. J. Neurol., 2015, 22: 24–30.
Search in Google Scholar Back to article
NICE, 2004; 2018. www.nice.org.uk/guidance/cg137
Search in Google Scholar Back to article
Patsalos P.N., Froscher W., Pisani F., van Rijn C.: The importance of drug interactions in epilepsy therapy. Epilepsia, 2002, 43: 365–385.
Search in Google Scholar Back to article
SIGN, 2003. www.sign.ac.uk/sign-143-diagnosis-and-management-of-epilepsy-in-adults.
Search in Google Scholar Back to article
Tellez-Zenteno J.F., Matijevic S., Wiebe S.: Somatic comorbidity of epilepsy in the general population in Canada. Epilepsia, 2005, 46: 1955–1962.
Search in Google Scholar Back to article
Tellez-Zenteno J.F., Patten S.B., Jette N., Williams J., Wiebe S.: Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia, 2007, 48: 2336–2344.
Search in Google Scholar Back to article
Thiele, E.A., Marsh, E.D., French, J.A., Mazurkiewicz, M.B., Benbadis, S.R., Joshi, C. and GWPCARE4 Study Group.: Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet, 2018, 391: 1085–1096.
Search in Google Scholar Back to article
Villanueva V., López F.J., Serratosa J.M., González-Giraldez B., Campos D., Molins A. et al: Control of seizures in different stages of partial epilepsy: LACO-EXP, a Spanish retrospective study of lacosamide. Epilepsy Behav., 2013, 29: 349–356. doi: 10.1016/j.yebeh.2013.07.024.
Open DOI Search in Google Scholar Back to article
Villanueva V., Garcés M., López-Gomáriz E., Serratosa J.M., González-Giráldez B., Parra J. and REALLY Study Group.: Early add-on lacosamide in a real-life setting: results of the REALLY study. Clin. Drug Investig., 2015, 35: 121–131. doi: 10.1007/s40261-014-0255-5.
Open DOI Search in Google Scholar Back to article
Weston J., Bromley R., Jackson C.F., Adab N., Clayton-Smith J., Greenhalgh J. et al.: Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst. Rev., 2016, 11: CD010224.
Search in Google Scholar Back to article
Zadeh W.W., Escartin A., Byrnes W., Tennigkeit F., Borghs S., Li T. and SP0954 Study Group: Efficacy and safety of lacosamide as first add-on or later adjunctive treatment for uncontrolled partial-onset seizures: A multicentre open-label trial. Seizure, 2015, 31: 72–79. doi: 10.1016/j.seizure.2015.07.001.
Open DOI Search in Google Scholar Back to article

Recommendations of the Polish Society of Epileptology for the treatment of epileptic seizure in adult patients in Poland: an update

Abstract

Introduction

Method

Discussion and recommendations

Paradigm

My account