Figure 1.
Figure 2.
Demographics
| Gender | Male 47 (49.5%) | Female 48 (50.5%) |
|---|---|---|
| Type of epilepsy | Temporal 49 (51.6%) | Extra-temporal 46 (48.4%) |
| Length of stay | Mean 3.57 days | Range 3–16 days |
| Age | Mean 43.3 years | Range 21–85 years |
| Weaning strategy | Remain on medications | n = 6 |
| Cutting doses | n = 12 | |
| Stop one by one | n = 57 | |
| Abrupt cessation | n = 20 |
Factors associated with time to first seizure: abrupt cessation of medications was used as a reference, this was compared to other withdrawal methods
| Time to first seizure | Hazard ratio (95%CI) | p-value |
|---|---|---|
| Years of seizures | 0.99 (0.98–1.01) | 0.42 |
| Seizure frequency | 1.00 (0.99–1.00) | 0.38 |
| Abrupt cessation | 1.0 (reference) | |
| Cut doses | 1.67 (0.74–3.77) | 0.22 |
| Stop one-by-one | 2.79 (1.53–5.09) | 0.00084 |
| Remain on medications | 7.01 (2.46–20) | 0.00027 |