Comparison of characteristics of newborns treated with phototherapy and/or blood transfusion by blood group (N = 72)
| Characteristic | Blood group A (n = 41) | Blood group B (n = 31) | p |
|---|---|---|---|
| Sex | |||
| M | 17 | 20 | 0.061 |
| F | 24 | 11 | |
| Mother’s D status | |||
| D+ | 28 | 18 | 0.459 |
| D– | 13 | 13 | |
| Delivery | |||
| Vaginal | 34 | 29 | 0.283 |
| Caesarean section | 7 | 2 | |
| Pregnancy order | |||
| First | 18 | 4 | NA |
| Second | 13 | 10 | |
| Third | 2 | 10 | |
| Fourth or more | 7 | 7 | |
| DAT+ | 39 | 29 | 1.000 |
| DAT+, number of hours from delivery | 19 (0–35.5) | 21 (8.75–36) | 0.773 |
| Beginning of hyperbilirubinemia, number of hours from delivery | 26.5 (18–38) | 28.5 (22.5–43) | 0.372 |
| Beginning of jaundice, day of life | 1.5 (1–2) | 2 (1–2) | 0.511 |
| Bilirubin, μmol/L* | |||
| Initial | 196 ± 50 | 197 ± 50 | 0.924 |
| Last | 198.5 (170–225.5) | 206 (173–229) | 0.736 |
| Hb, g/L† | |||
| Initial | 179 ± 24 | 177 ± 30 | 0.803 |
| Last | 157 ± 25 | 162 ± 29 | 0.587 |
| Days of phototherapy | 3 (2–4.5) | 2 (2–3) | 0.072 |
| Transfusion, % | 2 (5) | 0 | NA |
| IVIG, % | 1 (2.4) | 1 (3.2) | NA |
| Days of hospitalization | 6 (5–7) | 5 (4–6) | 0.067 |
Cases of ABO-incompatible siblings
| Case | Mother | Newborn | ||||||
|---|---|---|---|---|---|---|---|---|
| Identifier | ABO/D | Identifier | Year born | Sex | ABO/D | DAT | Treatment | |
| 1 | M1 | O,D– | N1-1 | 2017 | M | B, D– | Positive | None |
| N1-2 | 2019 | M | B, D– | Positive | Phototherapy | |||
| 2 | M2 | O, D– | N2-1 | 2018 | M | A, D+ | Positive | None |
| N2-2 | 2020 | F | A, D+ | Positive | None | |||
| 3 | M3 | O, D– | N3-1 | 2016 | M | A, D+ | Positive | None |
| N3-2 | 2018 | M | B, D– | Positive | Phototherapy | |||
| 4 | M4 | O, D+ | N4-1 | 2016 | F | B, D+ | Positive | Phototherapy |
| N4-2 | 2018 | M | B, D+ | Positive | Phototherapy | |||
| 5 | M5 | O, D+ | N5-1 | 2017 | F | B, D+ | Positive | Phototherapy |
| N5-2 | 2019 | M | B, D+ | Positive | Phototherapy | |||
| 6 | M6 | O, D– | N6-1 | 2018 | F | A, D+ | Positive | Phototherapy |
| N6-2 | 2020 | F | A, D+ | Positive | Phototherapy | |||
| 7 | M7 | O, D+ | N7-1 | 2016 | M | A, D– | Positive | Phototherapy |
| N7-2 | 2018 | F | A, D+ | Positive | Phototherapy | |||
| 8 | M8 | O, D– | N8-1 | 2016 | F | B, D– | Positive | Phototherapy |
| N8-2 | 2018 | M | A, D– | Positive | Phototherapy | |||
| 9 | M9 | O, D+ | N9-1 | 2016 | M | A, D+ | Positive | Phototherapy |
| N9-2 | 2018 | F | A, D+ | Positive | Phototherapy | |||
| N9-3 | 2020 | M | A, D+ | Positive | None | |||
| 10 | M10 | O, D+ | N10-1 | 2016 | F | B, D+ | Positive | Phototherapy |
| N10-2* | 2019 | F | Not tested | Not tested | Phototherapy | |||
Comparison of characteristics of treated and untreated newborns with maternal ABO incompatibility (N = 184)
| Characteristic | Untreated (n = 112) | Treated (n = 72) | p |
|---|---|---|---|
| Blood group | |||
| A | 75 | 41 | 0.115 |
| B | 34 | 31 | |
| AB | 3 | 0 | |
| DAT+ | 105 | 68 | 1.000 |
| DAT– | 7 | 4 | |
| Delivery | |||
| Vaginal | 77 | 63 | 0.004 |
| Caesarean section | 34 | 9 | |
| Unknown | 1 | 0 | |
| Sex | |||
| M | 57 | 37 | 1.000 |
| F | 55 | 35 | |
| Gestational age, weeks | 39 (39–40) | 39 (38–40) | 0.958 |
| Birth weight, g | 3425 | 3505 | 0.575 |
| DAT+, number of hours from delivery | 0 (0–16) | 20.5 (2.5–36) | <0.001 |
| Mother’s D status | |||
| D+ | 17 | 46 | <0.001 |
| D– | 95 | 26 | |