Immune hemolytic anemia following heart-lung transplantation

Perlman, E.J.; Shirey, R.S.; Farkosh, M.; Kickler, T.S.; Ness, R.M.

doi:10.21307/immunohematology-2019-981

Abstract

Immune hemolytic anemia due to minor ABO incompatibility between recipient and donor is a well-recognized occurrence in kidney and liver transplantation, In some cases, the responsible antibodies have been shown to be derived from the donor passenger lymphocytes using Gm allotyping. We report a case of acute, transient hemolysis following heart-lung transplantation in which serologic and Gm allotype studies confirmed the etiology of hemolysis. Immunohematalogy 1992;8:38–40

References

Allbrechtsen D, Solheim BG, Flatmark A, et al. Autoimmune hemolytic anemia in cyclosporine-treated organ allograft recipients. Transplant Proc 1988;20 (Suppl 3):959-62.
Search in Google Scholar Back to article
Angstadt J, Jarrell B, Maddrey W, et al. Hemolysis in ABO-incompatible liver transplantation. Transplant Proc 1987;19:4595-7.
Search in Google Scholar Back to article
Mangal AK, Growe GH, Sinclair M, Stillwell GF, Reeve CE, Naiman SC. Acquired hemolytic anemia due to “auto” anti-A or “auto” anti-B induced by group O homograft in renal transplant recipients. Transfusion 1982;24:201-5.10.1046/j.1537-2995.1984.24384225021.x6374996
Search in Google Scholar Back to article
Ramsey G, Nusbacher J, Starzl TE, Lindsay GD. Isohemagglutinins of graft origin after ABO-unmatched liver transplantation. N Eng J Med 1984;311:1167-70.10.1056/NEJM19841101311180729640686384786
Search in Google Scholar Back to article
Solheim BG, Allbrechtsen DA, Berg KJ, et al. Hemolytic anemia in cyclosporine-treated recipient of kidney or heart grafts from donors with minor incompatibility for ABO antigens. Transplant Proc 1987;19:4236-8.
Search in Google Scholar Back to article
Hunt BJ, Yacoub M, Amin S, Devenish A, Contreras M. Induction of red blood cell destruction by graft-derived antibodies after minor ABO-mismatched heart and lung transplantation. Transplantation 1988;46:246-9.10.1097/00007890-198808000-000123136561
Search in Google Scholar Back to article
Ramsey G. Red cell antibodies arising from solid organ transplants. Transfusion 1991;31:76-86.10.1046/j.1537-2995.1991.31191096190.x1986468
Search in Google Scholar Back to article
Bracey AW. Anti-A of donor lymphocyte origin in three recipients of organs from the same donor. Vox Sang 1987;53: 181-3.10.1111/j.1423-0410.1987.tb04946.x3318124
Search in Google Scholar Back to article
Swanson JL, Sastamoinen RM, Steeper TA, Sebring ES. Gm allotyping to determine the origin of red cell antibodies in recipients of solid organ transplant. Vox Sang 1987;52:75-8.10.1111/j.1423-0410.1987.tb02994.x3604171
Search in Google Scholar Back to article
Swanson J, Sebring E, Sastamoinen R, Chopek M. Gm allotyping to determine the origin of the anti-D causing hemolytic anemia in a kidney transplant recipient. Vox Sang 1987;52:228-30.10.1111/j.1423-0410.1987.tb03033.x3111092
Search in Google Scholar Back to article
Orchard J, Young NT, Smith C, Thomas S, Darke C. Severe intravascular hemolysis in a renal transplant recipient due to anti-B of donor origin. Vox Sang 1990;59:172-5.10.1111/j.1423-0410.1990.tb00853.x2264320
Search in Google Scholar Back to article
Walker RH, ed. Technical manual. 10th ed Arlington, VA: American Association of Blood Banks, 1990.
Search in Google Scholar Back to article
Bevan PC, Seaman M, Tolliday B, Chalmers DG. ABO hemolytic anemia in transplanted patients. Vox Sang 1985;49:42-8.10.1111/j.1423-0410.1985.tb00767.x3892896
Search in Google Scholar Back to article
Lundsgren G, Asaba H, Bergstrom J, et al. Fulminating anti-A autoimmune hemolysis with anuria in a renal transplant recipient: a therapeutic role of plasma exchange. Clinical Nephrology 1981;16:211-14.
Search in Google Scholar Back to article

Immune hemolytic anemia following heart-lung transplantation

Abstract

Paradigm

My account