Loss and reappearance of Rho(D) antigen on the red blood cells of an individual with acute myelogenous leukemia

K. Mohandas; V. Najfield; H. Gilbert; P. Azar; D. Skerrett

doi:10.21307/immunohematology-2019-940

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Loss and reappearance of Rho(D) antigen on the red blood cells of an individual with acute myelogenous leukemia

Immunohematology

Volume 10 (1994): Issue 4 (December 1994)

By: K. Mohandas, V. Najfield, H. Gilbert, P. Azar and D. Skerrett

Paid access

|Nov 2020

Abstract

Complete loss of Rh_o(D) antigen from red blood cells (RBCs) of individuals with hematologic disorders, though not frequent, has been reported. This case reports the loss of D antigen on the RBCs of a patient with acute myelogenous leukemia and its reappearance when he was in remission. Loss of D antigen expression coincided with worsening clinical and cytogenetic disease. At the time of D antigen loss, the patient also had cytogenetic abnormalities in the bone marrow cells. When he was in remission, the chromosomal abnormalities were no longer detectable, and his RBCs regained D antigen expression. Immunohematology 1994;10:134–135.

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Articles in this issue

DOI: https://doi.org/10.21307/immunohematology-2019-940 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X

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Language: English

Page range: 134 - 135

Published on: Nov 30, 2020

Published by: American National Red Cross

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Related subjects:

Medicine,

Clinical medicine,

Laboratory medicine

© 2020 K. Mohandas, V. Najfield, H. Gilbert, P. Azar, D. Skerrett, published by American National Red Cross
This work is licensed under the Creative Commons License.

Volume 10 (1994): Issue 4 (December 1994)