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Review: measuring red cell survival and determining the clinical significance of red cell antibodies Cover

Review: measuring red cell survival and determining the clinical significance of red cell antibodies

By: S. Nance  
Paid access
|Nov 2020

References

  1. Ashby W. The determination of the length of life of transfused blood corpuscles in man. J Exp Med 1919;29:267.10.1084/jem.29.3.267
  2. Postoway N, Nance S. O’Neill P, Garratty G. Comparison of a practical differential agglutination procedure to flow cytometry in following the survival of transfused red cells (abstract). Transfusion 1985;25:453.
  3. Nance ST. Flow cytometry as a diagnostic tool in transfusion medicine. In: Anderson K, Ness P, eds. Scientific basis of transfusion medicine. Philadelphia, PA: WB Saunders, in press.
  4. International Committee for Standardization in Haematology: recommended method for radioisotope red cell survival studies. BrJ Haematol 1980;45:659–66.10.1111/j.1365-2141.1980.tb07189.x
  5. Valinsky JE. The analysis of red cells by flow cytometry: applications in immunohematology. CPC Press 1989:169–90.
  6. Nance S, Amdt P, Garratty G. Predicting the clinical significance of red cell alloantibodies using a monocyte monolayer assay. Transfusion 1987;27:449–52.10.1046/j.1537-2995.1987.27688071692.x
  7. Schanfield MS. Schoeppner SL, Stevens JO. New approaches to detecting clinically significant antibodies in the laboratory. In: Sandler SG, Nusbacher J, Schanfield. MS, eds. Immunobiology of the erythrocyte. New York: Alan R. Liss, 1980:305–23.
  8. Branch DR, Gallagher MT, Mison AP, Sy Siok Hian AL, Petz LD. In vitro determination of red cell alloantibody significance using an assay of monocyte-macrophage interaction with sensitized erythrocytes. Br J Haematol 1984;56:19–29.10.1111/j.1365-2141.1984.tb01268.x
  9. van der Meulen FW, van der Hart M, Fleer A, von dem Borne AEG Kr, Engeifriet CP, van Loghem JJ. The role of adherence to human mononuclear phagocytes in the destruction of red cells sensitized with non-complement-binding IgG antibodies. BrJ Haematol 1978;38:541–9.10.1111/j.1365-2141.1978.tb01079.x
  10. Urbaniak SJ. Lymphoid cell-dependent (K-cell) lysis of human erythrocytes sensitized with rhesus alloantibodies. Br J Haematol 1976:33:409.10.1111/j.1365-2141.1976.tb03558.x
  11. Molthan L, Wick RW Jr, Gross BM. Extravascular hemolytic transfusion reactions due to anti-Yka + Csa. Rev Franc Transfus Immunohematol 1981;24:263–1.10.1016/S0338-4535(81)80205-X
  12. Davey RJ. Red cell radiolabeling in transfusion medicine. In: Davey RT, Wallace ME, eds. Diagnostic and investigational uses of radiolabeled blood elements. Arlington, VA: American Association of Blood Banks, 1987:39–66.
  13. Jones J, Mollison PL. A simple and efficient method of labelling red cells with 99mTc for determination of red cell volume. Br J Haematol 1978;38:141–8.10.1111/j.1365-2141.1978.tb07116.x638059
  14. Holt JT, Spitalnik SL, McMican AE, Wilson G, Blumberg N, A. technetium-99m red cell survival technique for in vivo compatibility testing. Transfusion 1983;23:148–51.10.1046/j.1537-2995.1983.23283172854.x6301115
  15. Marcus CS, Myhre BA. Angulo ML, Salk RD, Essex CE, Demianew SH. Radiolabeled red cell viability. I. Comparison of 51Cr, 99mTc, and 111In for measuring the viability of autologous stored red cells. Transfusion 1987;27:415–9.10.1046/j.1537-2995.1987.27587320536.x3629673
  16. Marcus CS, Myhre BA, Angulo MC, Salk RD, Essex CE, Demianew SH. Radiolabeled red cell viability. II 99mTc and 111In for measuring the viability of heterologous red cells in vivo. Transfusion 1987;27:420–4.10.1046/j.1537-2995.1987.27587320537.x
  17. Sioufi HA, Button LN, Jacobson MS, Kevy SV. Non-radioactive chromium technique for red cell labeling. Vox Sang 1990;58:204–6.10.1111/j.1423-0410.1990.tb02091.x
  18. Mollison PL, Engelfriet CP, Contreras M. Blood transfusion in clinical medicine. 9th ed. Oxford: Blackwell Scientific Publications, 1993.
  19. Silvergleid AJ, Wells RF, Hafleigh EB, Korn G, Kellner JJ, Grumet FC. Compatibility test using 51chromium-labeled red blood cells in crossmatch-positive patients. Transfusion 1978;18:8–14.10.1046/j.1537-2995.1978.18178118571.x
  20. Gray SJ, Sterling K. The tagging of red cells and plasma proteins with radioactive chromium. J Clin Invest 1950;29:1604–13.10.1172/JCI102403
  21. Ebaugh FG, Emerson CP, Ross JF. The use of radioactive chromium-51 as erythrocyte-tagging agent for the determination of red cell survival in vivo. J Clin Invest I953;32:1260–76.10.1172/JCI102855
  22. Mollison PL, Cutbush M. The use of isotope labelled red cells to demonstrate incompatibility in vivo. Lancet 1955;i:1290–5.10.1016/S0140-6736(55)92057-2
  23. Ebaugh FG, Ross JF. The radioactive sodium chromate method for erythrocyte survival. Vox Sang 1985;49:304–7.10.1111/j.1423-0410.1985.tb01126.x3904208
  24. Mollison PL. Survival curves of incompatible red cells, an analytical review. Transfusion 1986;26:43–50.10.1046/j.1537-2995.1986.26186124030.x3511574
  25. Evans RS, Turner E, Bingham M. Chronic hemolytic anemia due to cold agglutinins: the mechanism of resistance of red cells to C hemolysis by cold agglutinins. J Clin Invest 1967;46:1461–74.10.1172/JCI1056382928924166664
  26. Evans RS, Turner E, Bingham M, Woods R. Chronic hemolytic anemia due to cold agglutinins. II. The role of C′ in red cell destruction. J Clin Invest 1968;47:691–701.10.1172/JCI1057642972205641611
  27. Strumia MM, Colwell LS, Dugan A. The measure of erythropoiesis in anemias. I. The mixing time and immediate post-transfusion disappearance of T-1824 dye and of 51Cr-tagged erythrocytes in relation to blood volume determination. Blood 1958;13:128–45.10.1182/blood.V13.2.128.128
  28. Pineda AA, Dharker DD, Wahner HW, Clinical evaluation of a 51Cr-labeled red blood cell survival test for in vivo blood compatibility testing. Mayo Clin Proc 1984;59:25–30.10.1016/S0025-6196(12)60338-3
  29. Bentley SA, Collins ML, Miller DT. Interpretation of red cell survival data for in vivo compatibility testing: a normal value study. Br J Haematol 1987;67:241–4.10.1111/j.1365-2141.1987.tb02334.x3676111
  30. Myhre BA, Marcus CS, Wheeler NC. The prediction of autologous red cell survival. Ann Ciin Lab Sci 1990;20:258–62.
  31. Inam-ur-Rahman A, Siraj QH, Waqar A, Rathore S, Munir T, Ahmed SA. Patterns in 51chromium red cell survival and sequestration studies. JPMA 1990:40:283–8.
  32. Baldwin ML, Ness PM, Barrasso C, et al. In vivo studies of the long-term 51Cr red cell survival of serologically incompatible red cell units. Transfusion 1985;25:34–8.10.1046/j.1537-2995.1985.25185116499.x3969699
  33. Chaplin H, Hunter VL, Malecek AC, Kilzer P, Rosche ME. Clinically significant allo-anti-I in an I-negative patient with massive hemorrhage. Transfusion 1986;26:57–61.10.1046/j.1537-2995.1986.26186124032.x3946005
  34. Claflin AJ. Three members of one family with the phenotype in one with anti-I antibody. Transfusion 1963;3:216–9.10.1111/j.1537-2995.1963.tb04628.x14021467
  35. Schmidt PJ, McGinniss MH, Pappas NJ. Injection of incompatible red cell stroma in a patient with iso-antibody to I. In: 1964 Proc Int Soc Blood Transfusion, 1965:776–80.10.1159/0003843654160208
  36. Levy GJ, Selset G, McQuiston D, et al. Clinical significance of anti-Ytb. Report of a case using a 51chromium red cell survival study. Transfusion 1988;28:265–7.10.1046/j.1537-2995.1988.28388219157.x3285526
  37. AuBuchon JP, Brightman A, Anderson HJ, Kim B. An example of anti-Yta demonstrating a change in its clinical significance. Vox Sang 1988;55:171–5.
  38. Alderson G, Gray LS, Mintz PD. Red cell survival studies in a patient with anti-Tca. Am J Clin Pathol 1991;95:87–90.10.1093/ajcp/95.1.871987756
  39. Smith KJ, Coonce LS. South SF, Troup GM. Anti-Cra: family study and survival of chromium-labeled incompatible red cells in a Spanish-American patient. Transfusion 1983;23:167–9.10.1046/j.1537-2995.1983.23283172860.x6836696
  40. Whitsett CF, Oxendine SM. Survival studies with another example of anti-Cra. Transfusion 1991;31:782–3.10.1046/j.1537-2995.1991.31892023513.x
  41. Znojil V. An ignored error in the mathematical formulation of erythrocyte survival curves. J Theor Biol 1983;102:625–8.10.1016/0022-5193(83)90395-8
  42. Preisler HK. Computer-assisted red cell survival analysis. Computers and Biomedical Research 1984;17:509–23.10.1016/0010-4809(84)90016-8
  43. Kasfiki AG, Antipas SE, Dimitriou PA, Gritzali FA, Melissinos KG. Mathematical analysis of 51Cr-labeled red cell survival curves in congenital haemolytic anaemias. EurJ Nucl Med l982;7:181–3.10.1007/BF00443928
  44. Barosi G, Baraldi A, Bonomi F, et al. Competing models for the analysis of red cell survival obtained with 51Cr-labeling technique. Scand J Haematol 1983;31:381–8.10.1111/j.1600-0609.1983.tb00666.x
  45. Bonomi F, Stefanelli M. REDCE: a computer program for the analysis of red cell survival data. Computer Programs in Biomedicine 1980;12:172–82.10.1016/0010-468X(80)90063-X
  46. Davey RJ, Gustafson M, Holland PV. Accelerated immune red cell destruction in the absence of serologically detectable alloantibodies. Transfusion 1980;20:348–53.10.1046/j.1537-2995.1980.20380214905.x6770508
  47. Baldwin ML, Barrasso C, Ness PM, Garratty G. A clinically significant erythocyte antibody detectable only by 51Cr survival studies. Transfusion 1983;23:40–4.10.1046/j.1537-2995.1983.23183147303.x6402832
  48. Bode P, deBruin M, Oldenburg S, van der Wiel A, Wolterbeek B. A new technique for the study of erythrocyte survival by double labeling and use of a well-type Ge detector. Biological Trace Element Research 1990:111–8.10.1007/978-1-4612-0473-2_13
  49. de Vries RA, Oldenburg SJ, Thelosen T, deBruin M, Poortman J, van der Wiel A. New possibilities in erythrocyte survival studies with the application of a well-type germanium semiconductor detector. Nuclear Medicine Communications 1991;12:451–9.10.1097/00006231-199105000-000102067750
  50. Liddle CG, Putnam JP, Berman E, Fisher H, Ostby J. A comparison of chromium-51 and iron-59 for estimating erythrocyte survival in the cat. Lab Animal Science 1984;34:365–70.
  51. Cesareo R, Ciancarelli MG, Scarnati E. Determination of red cell survival in rabbits by fluorescent excitation analysis of stable rubidium. Med Phys 1980;7:97–100.10.1118/1.594671
  52. Valinsky JE, Marsh WL, Bianco C. Flow cytometric procedure for estimation of transfused erythrocyte survival “in vivo” (abstract). Transfusion 1985;25:478.
  53. DiNapoli J, Gingras A, Diggs E, Alicea-Tossas E, Kessler L. Survival of Ge+ red cells in a patient with anti-Gel,2: data from 51Cr. flow cytometry. IgG subclass, and macrophage erythrophagocytosis assays (abstract). Transfusion 1986;26:545.
  54. Issitt PD, ValinskyJ, Marsh WL, DiNapoli J, Gutgsell NS. In vivo destruction of antigen-positive red cells by anti-Lu6 (abstract). Transfusion 1987;27:548.
  55. Valinsky JE, Marsh WL, Bianco C. Estimation of the survival of transfused red cells in vivo by flow cytometry. International Society for Blood Transfusion (abstract). 1986:419.
  56. Nance S, Gonzales B, Postoway N, Vengelen-Tyler V, Garratty G. Clinical significance of a primarily complement-dependent anti-Jka in a patient who received Jk(a+) red cells (abstract). Transfusion 1985;25:482.
  57. Ratcliff D, Fiorenza S, Culotta E, Arndt P, Garratty G. Hydrops fetalis (HF) and a maternal hemolytic transfusion reaction associated with anti-Jsb (abstract). Transfusion 1987;27:534.
  58. Read EJ, Crabill HE, Davey RJ. Flow cytometric determination of transfused red blood cell (RBC) survival in a patient with autoimmune hemolytic anemia (AIHA) (abstract). Transfusion 1985:25:451.
  59. Pepkowitz S, Nance S, McQuiston D, Smith L, Capon S, Garratty G. Determining the volume of blood contained in transplanted organs using manual and flow cytometric methods. ISBT/ AABB Joint Congress (abstract). 1990:55.
  60. Crabill H, Davey R, AuBuchon J, Anderson G, Cupp J. Application of flow cytometry in the identification of minor cell populations (abstract). Transfusion 1985;25:474.
  61. Read EJ, Cardine L, Yu M. Flow cytometric detection of human red cells labeled with a fluorescent membrane label: potential application to in vivo survival studies. Transfusion 1991;31:502–8.10.1046/j.1537-2995.1991.31691306246.x
  62. Nance S, Garratty G. Applications of flow cytometry to immunohematology. J Immunol Methods 1987;101:127–31.10.1016/0022-1759(87)90225-0
  63. Kruskall M. Clinical management of transfusion to patients with red cell antibodies. In: Nance SJ, ed. Immune destruction of red blood cells. Arlington. VA: American Association of Blood Banks, 1989:263–84.
  64. Garratty G. Predicting the clinical significance of allo-antibodies and determining the in vivo survival of transfused red cells. In: Judd WJ, Barnes A, eds. Clinical and serological aspects of transfusion reactions: a technical workshop. Arlington, VA: American Association of Blood Banks, 1982:91–119.
  65. Engelfriet CP, von dem Borne AEG Kr, Beckers D, et al. Immune destruction of red cells. In: Bell CA, ed. A seminar on immune mediated cell destruction. Washington, DC: American Association of Blood Banks, 1981:93–130.
  66. Ouwehand WH. The activity of IgG1 and IgG3 antibodies in immune-mediated destruction of red cells; clinical significance in rhesus haemolytic disease of the newborn [Academic Thesis]. Amsterdam: Rodipi, 1984.
  67. Lucas GF, Hadley AG, Nance SJ, Garretty G. Predicting haemolytic disease of the newborn: a comparison of the monocyte monolayer assay and the chemiluminescence test. Transfusion 1993;3 3:484–7.10.1046/j.1537-2995.1993.33693296810.x8516790
  68. Archer GT. Erythrophagocytosis. Mod Med Aust 1964;7:55.
  69. Archer GT. Phagocytosis by human monocytes of red cells coated with Rh antibodies. Vox Sang 1965;10:590–8.10.1111/j.1423-0410.1965.tb01413.x4955862
  70. Brouwers HA. ABO haemolytic disease of the newborn. Immune mechanisms of red cell destruction and prognostic parameters [Academic Thesis]. The Netherlands: Offsetdrukkerij Kanters Alblasserdam, 1988.
  71. Nance S, Garratty G. Correlation between an in vitro monocyte monolayer assay and autoimmune hemolytic anemia (AIHA) (abstract). Transfusion 1982:22:410.
  72. Nance S, Nelson J, O’Neill P, Garratty G. Correlation of monocyte monolayer assays maternal antibody titers, and clinical course in hemolytic disease of the newborn (HDN) (abstract). Transfusion 1981:24:415.
  73. Nance S, Nelson J, Horenstein J, Arndt P, Platt L, Garratty G. Monocyte monolayer assay—an efficient non-invasive technique for predicting the severity of hemolytic disease of the newborn. Am J Clin Patholol 1989;92:89–92.10.1093/ajcp/92.1.892750714
  74. Sacks DA, Garratty G, Nance SJ, Petrucha RA, Horenstein J, Fotheringham N. The monocyte monolayer assay as a predictor of severity of erythroblastosis fetalis. Am J Perinatology 1993;10:428–31.10.1055/s-2007-9946238267805
  75. Zupanska B, Thomson EE, Brogjer E, Merry AH. Phagocytosis of erythrocytes sensitized with known amounts of IgG1 and IgG3 anti-Rh antibodies. Vox Sang 1987;53:96–101.10.1159/000461705
  76. Zupanska B, Brogjer E, Richards Y, Lenkiewicz B, Seyfield H, Howell P. Serological and immunological characteristics of maternal anti-Rh(D) antibodies in predicting the severity of haemolytic disease of the newborn. Vox Sang 1989;56:247–53.10.1111/j.1423-0410.1989.tb02037.x2503936
  77. Zupanska B, Brogjer E, Thomson EE, Merry AH, Seyfried H. Monocyte-erythrocyte interaction in autoimmune haemolytic anaemia in relation 1:0 the number of erythrocyte-bound IgG molecules and subclass specificity of autoantibodies. Vox Sang 1987;52:212–8.10.1111/j.1423-0410.1987.tb03030.x3604180
  78. Brogjer E, Zupanska B, Michaelewska B. Adherence to human monocytes of red cells from autoimmune haemolytic anaemia and red cells sensitized with alloantibodies. Haematologia 1982:15:135–45.
  79. Schanfield MS. The role of mononuclear phagocytes in RBC destruction: in vitro test systems. In: Chaplin H Jr, ed. Immune hemolytic anemia. New York: Churchill Livingstone, 1985: 135-53.
  80. Schanfield MS, Stevens JO, Bauman D. The detection of clinically significant erythrocyte antibodies using a human mononuclear phagocyte assay. Transfusion 1981 ;21:571–6.10.1046/j.1537-2995.1981.21582040822.x
  81. Schoeppner-Esty S, Chin J, Mallory D, Davey R. A comparison of the MMA to the 51Cr RBC survival for determining the clinical significance of red cell alloantibodies. Blood 1986;68(Suppl 1):302A.
  82. Branch DR, Gallagher MT. Correlation of in vivo alloantibody significance or insignificance with an in vitro monocyte-monolayer assay. BrJ Haematol 1986;62:783–5.10.1111/j.1365-2141.1986.tb04106.x
  83. Abramson N, Schur PH. The IgG subclasses of red cell antibodies and relationship to monocyte binding. Blood 1972;40:500–8.10.1182/blood.V40.4.500.500
  84. Hunt JS, Beck ML, Hardman JT, Tegtmeier GE, Bayer WL. Characterization of human erythrocyte antibodies by IgG subclass and monocyte interaction. Am J Clin Pathol 1980;74:259–64.10.1093/ajcp/74.3.259
  85. Garratty G, Nance S, O’Neill P. Factors that affect interpretation of monocyte monolayer assays (abstract). Transfusion 1986;26:570.
  86. Garratty G. Predicting the clinical significance of red cell antibodies with in vitro cellular assays. Transfus Med Rev 1990;IV:297–312.10.1016/S0887-7963(90)70272-6
  87. Nance SJ, Arndt PA, Garratty G. The effect of fresh normal serum on monocyte monolayer assay reactivity. Transfusion 1988;28:398–9.10.1046/j.1537-2995.1988.28488265281.x3388490
  88. Judd WJ, Oberman HA, Silenicks A, et al. Clinical significance of anti-Lan (letter). Transfusion 1984:24:181.10.1046/j.1537-2995.1984.24284173358.x6585080
  89. Issitt PD, Gutgsell NS, Hervis L. Some stored antibodies give unreliable results in the monocyte monolayer assay. Transfusion 1988;28:399–400.10.1046/j.1537-2995.1988.28488265282.x3388491
  90. Branch DR, Gallagher MT. The importance of CO2 in short-term monocyte-macrophage assays (letter). Transfusion 1985;25:399.10.1046/j.1537-2995.1985.25485273829.x3927533
DOI: https://doi.org/10.21307/immunohematology-2019-784 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X
Language: English
Page range: 31 - 38
Published on: Nov 17, 2020
Published by: American National Red Cross
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 S. Nance, published by American National Red Cross
This work is licensed under the Creative Commons License.