Quantifying the loss of ABO antigenicity in a patient with acute myeloid leukemia by flow cytometric analysis

Popp, H.J.; Nelson, M.; Forsyth, C.; Falson, M.; Kronenberg, H.

doi:10.21307/immunohematology-2019-777

.blurhash-client-img { display: none !important; }

Quantifying the loss of ABO antigenicity in a patient with acute myeloid leukemia by flow cytometric analysis

Immunohematology

Volume 11 (1995): Issue 1 (March 1995)

By: H.J. Popp, M. Nelson, C. Forsyth, M. Falson and H. Kronenberg

Paid access

|Nov 2020

Abstract

The loss of B antigenicity from the red blood ceils of a patient with acute myeloid leukemia is reported. The patient had normal B transferase levels, but had reduced levels of H transferase. Flow cytometry was used to quantify the loss of B antigenicity and monitor the expression of the B antigen throughout the progression of the disease.

References

Issitt PD. Applied blood group serology. 3rd ed. Miami: Montgomery Scientific Publications, 1985.
Search in Google Scholar Back to article
Kuhns WJ, Oliver RTD, Watkins WM, Greenwell P. Leukaemia-induced alterations of serum glycosyltransferase enzymes. Cancer Res 1980:40:268–75.
Search in Google Scholar Back to article
Green REB, Ford DS, Condon JA, Lowe VA. Basic blood grouping techniques and procedures. 2nd ed. Melbourne. Australia: Victorian Immunohaematology Discussion Group, 1992.
Search in Google Scholar Back to article
Badet J, Ropars C, Salmon C. α-N-acetyl-D-galactosaminyl and α-D-galactosyltransferase activities in sera of cis AB blood group individuals. J Immunogenet 1978:5:221–31.10.1111/j.1744-313X.1978.tb00650.x
Search in Google Scholar Back to article
Chester MA, Yates AD, Watkins WM. Phenyl-D-galactopyranoside as an acceptor substrate for the blood group H gene-associated guanosine diphosphate-L-fucose; β-D-galactosyl α-2-L-fucosyitransferase. Eur J Biochem 1976;69:583–92.10.1111/j.1432-1033.1976.tb10944.x
Search in Google Scholar Back to article
Marsden KA, Pearse AM, Collins GG, Ford DS, Heard S, Kimber R. Acute leukemia with t{1;3}{p36;q21}, t{14; 17}{q32;q21}, and loss of red cell A and Le^b antigens. Cancer Genet Cytogenet 1992;64:80–5.10.1016/0165-4608(92)90328-6
Search in Google Scholar Back to article

DOI: https://doi.org/10.21307/immunohematology-2019-777 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X

Journal RSS Feed

Language: English

Page range: 5 - 7

Published on: Nov 17, 2020

Published by: American National Red Cross

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Related subjects:

Medicine,

Clinical medicine,

Laboratory medicine

© 2020 H.J. Popp, M. Nelson, C. Forsyth, M. Falson, H. Kronenberg, published by American National Red Cross
This work is licensed under the Creative Commons License.

Previous article Volume 11 (1995): Issue 1 (March 1995)Next article