Severe intravascular hemolysis due to autoantibodies stimulated by blood transfusion

D. Chan; G.D. Poole; M. Binney; M.D. Hamon; J.A. Copplestone; A.G. Prentice

doi:10.21307/immunohematology-2019-751

Severe intravascular hemolysis due to autoantibodies stimulated by blood transfusion

Immunohematology

Volume 12 (1996): Issue 2 (June 1996)

By: D. Chan, G.D. Poole, M. Binney, M.D. Hamon, J.A. Copplestone and A.G. Prentice

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Abstract

Autoantibodies may cause severe hemolytic anemia, but only rarely are they the cause of a hemolytic transfusion reaction due to the destruction of transfused allogeneic blood. In two patients, autoantibody was detected shortly after blood transfusion. The first case was a D-negative patient who produced an autoanti-Ce and subsequently developed hemoglobinuria and hyperbilirubinemia. The second case was a patient who developed an autoanti-Wr^b that caused severe hemolysis that resulted in death. Immunohematology 1996;12:80–83.

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Articles in this issue

DOI: https://doi.org/10.21307/immunohematology-2019-751 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X

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Language: English

Page range: 80 - 83

Published on: Nov 10, 2020

Published by: American National Red Cross

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Related subjects:

Medicine,

Clinical medicine,

Laboratory medicine

© 2020 D. Chan, G.D. Poole, M. Binney, M.D. Hamon, J.A. Copplestone, A.G. Prentice, published by American National Red Cross
This work is licensed under the Creative Commons License.

Volume 12 (1996): Issue 2 (June 1996)