Report on anti-Dib encountered in two Hong Kong Chinese

Lin, C.K.; Mak, K.H.; Chan, N.K.; Yuen, C.M.Y.; Devenish, A.; Chan, H.B.; Au, K.L.; Szeto, S.C.

doi:10.21307/immunohematology-2019-695

Abstract

Two cases of anti-Di^b, a rarely encountered antibody, were identified in serum samples referred by hospital blood banks during the past 13 months. Case 1 is a 4l-year-old female who required blood for elective surgery. Case 2 is a premature infant suffering from mild neonatal jaundice on day 2 after birth. The anti-Di^b in both cases exhibited marked dosage effect. The titer/score against Di(a+b+) and Di(a-b+) red blood cells (RBCs) in case 1 was 8/10 and 32/32, respectively, and in case 2, 4/18 and 32/46. The monocyte monolayer assay (MMA) also gave a similar pattern of results, being l5 percent and 100 percent reactive when tested with Di(a+b+) and Di(a-b+) RBCs in case 1, and 0.4 percent (within normal range) and l4.4 percent in case 2. The patient in case 1 underwent her operation without blood transfusion. The infant in case 2 was treated by phototherapy and subsequently recovered without the need for exchange transfusion. Immunohematology 1997;13:17–19.

References

Daniels G. Human blood groups. Oxford: Blackwell Science, 1995:452-65.
Search in Google Scholar Back to article
Levine P, Robinson EA, Layrisse M, Arends T, Dominques SR. The Diego blood factor. Nature 1956;277:40-1.10.1038/177040b013288586
Search in Google Scholar Back to article
Thompson PR, Childers DM, Hatcher DE. Anti-Di^b—first and second examples. Vox Sang 1967;13:314-8.10.1111/j.1423-0410.1967.tb03114.x4104355
Search in Google Scholar Back to article
Mollison PL, Engelfriet CP, Contreras M. Blood transfusion in clinical medicine. 9th ed. Oxford: Blackwell Science, 1993: 268-9.
Search in Google Scholar Back to article
Lin-Chu M, Broadberry RE, Chang FC, Ting F. Haemolytic disease of the newborn (HDN) due to maternal anti-Di^b in a Chinese infant. In: Book of Abstracts of the Second Regional Congress, Western Pacific Region of International Society of Blood Transfusion, Hong Kong; 1991:32.
Search in Google Scholar Back to article
[6]Zafar M, Reid ME. Review: the Diego blood group system. Immunohematology 1993;9:35-40. 7.Mak KH, Cheng S, Yuen C, Chua E, Lin CK, Leong S. Survey of blood group distribution among Chinese blood donors in Hong Kong—an update. Vox Sang 1994;67:82-94.
Back to article
Walker RH, ed. Techical manual. 11th ed. Bethesda, MD: American Association of Blood Banks, 1993.
Search in Google Scholar Back to article
Marsh WL. Scoring of hemagglutination reactions. Transfusion 1972;12:352-3.10.1111/j.1537-2995.1972.tb04459.x5072588
Search in Google Scholar Back to article
Nance SJ, Arndt P, Garratty G. Predicting the clinical significance of red cell alloantibodies using a monocyte monolayer assay. Transfusion 1987;27:449-52.10.1046/j.1537-2995.1987.27688071692.x3686653
Search in Google Scholar Back to article
Schanfield MS, Schoeppner SL, Stevens JO. New approaches to detecting clinically significant antibodies in the laboratory. In: Sandler SG, Nusbacher J, Schanfield MS, eds. Immunobiology of the erythrocyte. New York: Alan R. Liss, 1980:305-23.
Search in Google Scholar Back to article
Habash J, Devenish A, Macdonald S, Garner S, Contreras M. A further example of anti-Di^b not causing haemolytic disease of the newborn. Vox Sang 1991;61:77.
Search in Google Scholar Back to article
Feller CW, Shenker L, Scott EP, Marsh WL. An anti-Diego (Di^b) antibody occurring during pregnancy. Transfusion 1970;10: 279-80.10.1111/j.1537-2995.1970.tb00743.x4990256
Search in Google Scholar Back to article
Uchikawa M, Shibata Y, Tohyama H, Mori H, Aisaka K, Nakagawa M. A case of haemolytic disease of the newborn due to anti-Di^b antibodies. Vox Sang 1982;42:91-2.10.1159/000460854
Search in Google Scholar Back to article
Issitt PD. Applied blood group serology. 3rd ed. Miami, FL: Montgomery Scientific Publications, 1985:387.
Search in Google Scholar Back to article
Orlina AR, Unger PJ. Hemolytic disease of the newborn due to anti-Di^b. Am J Clin Pathol 1979;71:713-4.10.1093/ajcp/71.6.713453088
Search in Google Scholar Back to article
Nance SJ, Nelson JM, Horenstein J, Arndt PA, Platt LD, Garratty G. Monocyte monolayer assay: an efficient noninvasive technique for predicting the severity of hemolytic disease of the newborn. Am J Clin Pathol 1989;92:89-92.10.1093/ajcp/92.1.892750714
Search in Google Scholar Back to article
Zupanska B, Brojer E, Richards Y, Lenkiewicz B, Seyfried H, Howell P. Serological and immunological characteristics of maternal anti-Rh(D) antibodies in predicting the severity of haemolytic disease of the newborn. Vox Sang 1989;56:247-53.10.1111/j.1423-0410.1989.tb02037.x2503936
Search in Google Scholar Back to article
Schanfield MS, Stevens JO, Bauman D. The detection of clinically significant erythrocyte alloantibodies using a human mononuclear phagocyte assay. Transfusion 1981;21:571-6.10.1046/j.1537-2995.1981.21582040822.x6794195
Search in Google Scholar Back to article
Branch DR, Gallagher MT. Correlation of in vivo alloantibody significance or insignificance with an in vivo monocytemacrophage phagocytosis assay. Br J Haematol 1986;62:783-5.10.1111/j.1365-2141.1986.tb04106.x3964567
Search in Google Scholar Back to article
Lucas GF, Hadley AG, Nance SJ, Garratty G. Predicting hemolytic disease of the newborn: a comparison of the monocyte monolayer assay and the chemiluminescence test. Transfusion 1993;33:484-7.10.1046/j.1537-2995.1993.33693296810.x8516790
Search in Google Scholar Back to article
Sacks DA, Nance SJ, Garratty G, Petrucha RA, Horenstein J, Fotheringham N. Monocyte monolayer assay as a prediction of severity of hemolytic disease of the fetus and newborn. Am J Perinatol 1993;10:428-31.10.1055/s-2007-9946238267805
Search in Google Scholar Back to article

Report on anti-Dib encountered in two Hong Kong Chinese

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