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Evaluation of monoclonal anti-A reagents by salivary inhibition studies Cover

Evaluation of monoclonal anti-A reagents by salivary inhibition studies

Paid access
|Dec 2020

Abstract

Ten commercially available monoclonal and polyclonal anti-A reagents were evaluated for use in the test for ABH secretor status after finding unexpected inhibition with a monoclonal anti-A (reagent Z). Two of the available monoclonal reagents were from different batches from the same clone as reagent Z. Those two reagents, as well as reagent Z, appeared to be partially neutralized by salivary substances from group A non-secretor individuals. This finding suggests that when a saliva inhibition test is done, a nonsecretor control saliva of the same ABO group as the saliva to be tested should be used.

DOI: https://doi.org/10.21307/immunohematology-2019-1109 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X
Language: English
Page range: 75 - 78
Published on: Dec 29, 2020
Published by: American National Red Cross
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 S.M. Henry, Benny A.G., D.G. Woodfield, published by American National Red Cross
This work is licensed under the Creative Commons License.