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Use of standard laboratory methods to obviate routine dithiothreitol treatment of blood samples with daratumumab interference Cover

Use of standard laboratory methods to obviate routine dithiothreitol treatment of blood samples with daratumumab interference

Paid access
|Oct 2019

References

  1. Lonial S, Weiss BM, Usmani SZ, et al. Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial. Lancet 2016;387:1551–60.10.1016/S0140-6736(15)01120-4
  2. De Vooght KMK, Oostendorp M, Van Solinge WW. New mAb therapies in multiple myeloma: interference with blood transfusion compatibility testing. Curr Opin Hematol 2016;23:557–62.10.1097/MOH.000000000000027627389485
  3. Chapuy CI, Nicholson RT, Aguad MD, et al. Resolving the daratumumab interference with blood compatibility testing. Transfusion 2015;55:1545–54.10.1111/trf.1306925764134
  4. van de Donk NW, Moreau P, Plesner T, et al. Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma. Blood 2016;127:681–96.10.1182/blood-2015-10-64681026631114
  5. Mehta K, Shahid U. CD38: a cell-surface protein with multiple functions. FASEB J 1996;10:1408–17.10.1096/fasebj.10.12.89035118903511
  6. AABB Association Bulletin #16-02 Mitigating the Anti-CD38 Interference with Serologic Testing. 2016. Available from https://www.aabb.org/programs/publications/bulletins/Documents/ab16-02.pdf.
  7. Chapuy CI, Aguad MD, Nicholson RT, et al. International validation of a dithiothreitol (DTT)-based method to resolve the daratumumab interference with blood compatibility testing. Transfusion 2016;12: 2964–72.10.1111/trf.1378927600566
  8. Cooling L, Downs T. Immunohematology. In: Hutchinson R, McPherson R, Schexneider K, eds. Henry’s clinical diagnosis and management by laboratory methods. 22nd ed. Philadelphia, PA: Elsevier Saunders 2011:674–730.10.1016/B978-1-4377-0974-2.00035-X
  9. Schmidt AE, Kirkley S, Patel N, et al. An alternative method to dithiothreitol treatment for antibody screening in patients receiving daratumumab. Transfusion 2015;55:2292–3.10.1111/trf.1317426372917
  10. Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, eds. Technical manual. 18th ed. Bethesda, MD: AABB, 2014.
DOI: https://doi.org/10.21307/immunohematology-2019-005 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X
Language: English
Page range: 22 - 26
Published on: Oct 9, 2019
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2019 N.J. Lintel, D.K. Brown, D.T. Schafer, F.M. Tsimba-Chitsva, S.A. Koepsell, S.M. Shunkwiler, published by American National Red Cross
This work is licensed under the Creative Commons License.