Sulfhydryl treatment of serum or plasma for the reduction of IgM antibodies
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Paid access
|Oct 2019Abstract
Dithiothreitol (DTT) and 2-mercaptoethanol (2-ME) are sulfhydryl compounds that can be used to treat serum or plasma to denature IgM antibody reactivity. By using sulfhydryl agents, IgG and IgM antibodies can be separated, the relative amount of IgM and IgG antibodies can be determined, and the risk of hemolytic disease of the fetus and newborn can be assessed. Immunohematology 2018;34:135–139.
DOI: https://doi.org/10.21307/immunohematology-2018-021 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X
Language: English
Page range: 135 - 139
Published on: Oct 16, 2019
Published by: American National Red Cross
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
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© 2019 L.N. Blagg, published by American National Red Cross
This work is licensed under the Creative Commons License.