Risk Assessment Criteria for Abnormal Glucose Metabolism as followed by CASA and other jurisdictions
| Aviation Authority | Diagnosis to be established | Tests to establish the diagnosis |
|---|---|---|
| ICAO | Diabetes | Oral glucose tolerance test (OGTT) |
| CASA | Abnormal glucose metabolism and cardiac risk | Fasting plasma glucose, OGTT, Cardiac risk index |
| Federal Aviation Authority (FAA) | Diabetes | Supporting Laboratory findings |
| Civil Aviation Authority, UK | Abnormal metabolism | Tests to establish abnormal glucose metabolism |
| European Aviation Safety Authority | Diabetes | OGTT |
| Transport Canada | Diabetes | Fasting plasma glucose, or HbA1c, or OGTT, or random plasma glucose |
| Civil Aviation Authority, New Zealand | Abnormal glucose metabolism | Acceptable biochemical criteria |
Risk estimates for cardiovascular disease among those with abnormal glucose tolerance test (Modified from Santaguida et_ al_ [30])
| Impaired Fasting Glucose (IFG) (95% CI* in parentheses) | Impaired Glucose Tolerance (IGT) (95% CI in parentheses) | |
|---|---|---|
| a. Risk for non-fatal CVD outcome | ||
| (i) Annualised risk estimates for any nonfatal CVD event | 0.63 – 9.68 | 11.58 – 12.39 |
| (ii) Unadjusted annualised relative risk | 1.24 (1.08 – 1.43) to 1.41 (1.17 – 1.69) | 2.43 (1.44 – 4.10) to 2.46 (1.46 – 4.12) |
| (iii) Attributable risk in the exposed group | 0% – 32.9% | 52.8% – 52.9% |
| b. Risk for fatal CVD outcome | ||
| (i) Annualised risk per 100 persons in the exposed groups | 01.10 – 1.54 | 0.06 – 0.76 |
| (ii) Unadjusted annualised relative risk | 1.32 (1.04 – 1.72) | 1.67 (1.23 – 2.26) to 3.08 (1.47 – 6.47) |
| (iii) Attributable risk in the exposed group. | 11.8% – 39.5% | 24.8% – 67.3% |
| c. Risk for mortality | ||
| (i) Annualised risk per 100 persons in the exposed groups | 0.56 – 1.39 | 0.09 – 2.44 |
| (ii) Unadjusted annualised relative risk | 1.18 (1.03 – 1.35) to 1.45 (1.27 – 1.66) | 1.36 (1.12 – 1.66) to 3.18 (1.79 – 5.63) |
| (iii) Attributable risk in the exposed group | 13.9% – 61.2% | 0% – 67.2% |