Abstract
Lateral cephalograms and orthopantomograms (OPGs) are often taken prior to the commencement of orthodontic treatment to assist in diagnosis and treatment planning. Further radiographs may be taken during treatment to monitor progress. It is the responsibility of the practitioner to carefully and thoroughly assess all aspects of the radiographs, both orthodontic and non-orthodontic. In the case presented, a radiolucency in the right mandible was identified in a mid-treatment OPG. Following referral to an oral maxillofacial surgeon for opinion and management, the lesion was biopsied and a specimen sent for histological examination. This case highlights the need for the orthodontic clinician to assess not only the state of orthodontic treatment, but also the overall clinical presentation and any radiographs that may be taken.