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Small Colony Variants – The Cause Of Chronic Infections Cover

Small Colony Variants – The Cause Of Chronic Infections

Open Access
|Sep 2021

References

  1. Askar M., Bloch B., Bayston R.: Small-colony variant of Staphylococcus lugdunensis in prosthetic joint infection. Arthroplasty Today, 4, 257–260 (2018)
  2. Becker K., Heilmann Ch., Peters G.: Coagulase-Negative Staphylococci. Clin Microbiol Rev. 27, 870–926 (2014)
  3. Bhattacharyya S., Roy S., Mukhopadhyay P.K., Rit K., Dey J.B., Ganguly U., Ray R.: Small Colony variants of Staphylococcus aureus isolated from a patient with infective endocarditis: a case report and review of the literature. Iran J. Microbiol. 4, 98–99 (2012)
  4. Bogut A., Niedźwiadek J., Kozioł-Montewka M., Strzelec-Nowak D., Blacha J., Mazurkiewicz T., Marczyński W., Plewik D.: Characterization of Staphylococcus epidermidis and Staphyloccocus warneri small-colony variants associated with prosthetic-joint infections. J. Med. Microbiol. 63, 176–185 (2014)
  5. Cao S., Huseby D.L., Brandis G., Hughes D.: Alternative evolutionary pathways for drug-resistant small colony variant mutants in Staphylococcus aureus. Mbio, 8, e00358–17 (2017)
  6. Cheung G.Y.C., Bae J.S., Otto M.: Pathogenicity and virulence of Staphylococcus aureus. Virulence, 12, 547–569 (2021)
  7. Churkina L.N., Bidnenko S.I., Lopes dos Santos Santiago G., Vaneechoutte M., Avdeeva L.V., Lutko O.B., Oserjanskaja N.M.: Application of the antibiotic batumin for accurate and rapid identification of staphylococcal small colony variants. BMC Res. Notes. 5, DOI: 10.1186/1756-0500-5-374 (2012)
  8. de Vor L., Rooijakkers S.H.M., van Strijp J.A.G.: Staphylococci evade the innate immune response by disarming neutrophils and forming biofilms. FEBS Letters, 594, 2556–2569 (2020)
  9. Egido S.H., Ruiz M.S., Inés Revuelta S., García I.G., Bellido J.L.: Enterococcus faecium small colony variant endocarditis in an immunocompetent patient. New Microbes New Infect. 14, 47–49 (2015)
  10. Farnia P., Farnia P., Ghanavi J., Zhavnerko G.K., Poleschuyk N.N., Velayati A.A.: A review on the shape changes in pathogenic bacteria with emphasis on Mycobacterium tuberculosis. Biomed. Biotechnol. Res. J. 2, 242–246 (2018)
  11. Garcia L.G., Lemaire S., Kahl B.C., Becker K., Proctor R.A., Denis O., Tulkens P.M., Van Bambeke F.: Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data. J. Antimicrob. Chemother. 68, 1455–1464 (2013)
  12. Häußler S., Tümmler B., Weißbrodt H., Rohde M., Steinmetz I.: Small-Colony Variants of Pseudomonas aeruginosa in Cystic Fibrosis, Clin. Infect. Dis. 29, 621–625 (1999)
  13. Ierardi E., Losurdo G., Mileti M., Paolillo R., Giorgio F., Principi M., Di Leo A.: The puzzle of coccoid forms of Helicobacter pylori: beyond basic science. Antibiotics, 9, DOI: 10.3390/antybiotyki9060293
  14. Irvine S., Bunk B., Bayes H.K., Spröer C., Connolly J.P.R., Six A., Evans T.J., Roe A.J., Overmann J., Walker D.: Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model. Microb. Genom. 5, DOI: 10.1099/mgen.0.000262 (2019)
  15. Jiang B., Hu X.: i wsp. Clinical Staphylococcus argenteus Develops to Small Colony Variants to Promote Persistent Infection. Front. Microbiol. 9, DOI: 10.3389/fmicb.2018.01347 (2018)
  16. Kahl B.C., Becker K., Löffler B.: Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections. Clin. Microbiol. Rev. 29, 401–427 (2016)
  17. Karauzum H., Datta S.K.: Adaptive immunity against Staphylococcus aureus. Curr Top. Microbiol. Immunol. 409, 419–439 (2017)
  18. Kołodyński J., Ledzińska M., Jankowski S.: Zakażenia bakteryjne a mukowiscydoza. Adv. Clin. Exp. Med. 13, 471–476 (2004)
  19. Kriegeskorte A., Lorè N.I., Bragonzi A., Riva C., Kelkenberg M., Becker K., Proctor R.A., Peters G., Kahl B.C.: Thymidine-dependent Staphylococcus aureus small-colony variants are induced by trimethoprim-sulfamethoxazole (SXT) and have increased fitness during SXT challenge. Antimicrob. Agents. Chemother. 59, 7265–7272 (2015)
  20. Krzyżek P., Grande R.: Review transformation of Helicobacter pylori into coccoid forms as a challenge for research determining activity of antimicrobial substances. Pathogens, 9, DOI: 10.3390/pathogens9030184 (2020)
  21. Lee J., Zilm P.S., Kidd S.P.: Novel research models for Staphylococcus aureus small colony variants (scv) development: co-pathogenesis and growth rate. Front. Microbiol. 11, DOI: 10.3389/fmicb.2020.00321 (2020)
  22. Lin Y.T., Tsai J.C., Yamamoto T., Chen H.J., Hung W.C., Hsueh P.R., Teng L.J.: Emergence of a small colony variant of vancomycin-intermediate Staphylococcus aureus in a patient with septic arthritis during long-term treatment with daptomycin. J Antimicrob. Chemother. 71, 1807–1814 (2016)
  23. Loss G., Laurent F.: i wsp. Staphylococcus aureus Small Colony Variants (SCVs): News from a chronic prosthetic joint infection. Front. Cell. Infect. Microbiol. 9, DOI: 10.3389/fcimb.2019.00363 (2019)
  24. Louise Cullen L., McClean S.: Bacterial Adaptation during Chronic Respiratory Infections. Pathogens, 4, 66–89 (2015)
  25. Magryś A., Deryło K., Bogut A., Olender A., Tchórzewski M.: Intraphagolysosomal conditions predispose to Staphylococcus epidermidis small colony variants persistence in macrophages. Plos One, 13, e0207312 (2018)
  26. Malone J.G.: Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs. Infect. Drug Resist. 8, 237–247 (2015)
  27. Mauch R.M., Jensen P.Ø., Moser C., Levy C.E., Høiby N.: Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis. J. Cyst. Fibros. 17, 143–152 (2018)
  28. Meriläinen L., Herranen A., Schwarzbach A., Gilbert L.: Morphological and biochemical features of Borrelia burgdorferi pleomorphic forms. Microbiology, 161, 516–527 (2015)
  29. Mirani Z.A., Urooj S., Zeesahn F., Kha M.N., Aziz M., Shaikh I.A., Khan A.B.: Role of phenotypic switching in stability and persistence of Pseudomonas aeruginosa biofilms. J. Microbiol. Infect. Dis. 10, 10–17 (2020)
  30. Müsken M., Klimmek K., Sauer-Heilborn A., Donnert M., Sedlacek L., Suerbaum S., Häussler S.: Towards individualized diagnostics of biofilm-associated infections: a case study. NPJ Biofilms Microbiomes, 28, DOI: 10.1038/s41522-017-0030-5 (2017)
  31. Nagano N., Kawakami Y., Matsumoto T., Tanimoto K., Kashihara M., Nagata M., Honjyo H., Yamamoto K., Takada A., Sugiura T.: Isolation of thymidine-dependent and extended-spectrum-β-lactamase-producing Escherichia coli small-colony variant from urine of a septuagenarian female patient with recurrent cystitis: A case report with genetic investigation. J. Infect. Chemother. 26, 1066–1069 (2020)
  32. Noble S.M., Gianetti B.A., Witchley J.N.: Candida albicans cell type switches and functional plasticity in the mammalian host. Nat. Rev. Microbiol. 15, 96–108 (2017)
  33. Onyango L.A., Hugh Dunstan R., Roberts T.K., Macdonald M.M., Gottfries J.: Phenotypic variants of staphylococci and their underlying population distributions following exposure to stress. Plos One, 8, e77614 (2013)
  34. Ou J.J.J., Drilling A.J., Cooksley C., Bassiouni A., Kidd S.P., Psaltis A.J., Wormald P.J., Vreugde S.: Reduced innate immune response to a Staphylococcus aureus small colony variant compared to its wild-type parent strain. Front. Cell. Infect. Microbiol. 6, DOI: 10.3389/fcimb.2016.00187 (2016)
  35. Park Y.J., Le Phuong N., Pinto N.A., Kwon M.J., D’Souza R., Byun J.H., Sung H., Yong D.: Urinary tract infection caused by a small colony variant form of capnophilic Escherichia coli leading to misidentification and non-reactions in antimicrobial susceptibility tests. Antimicrob. Resist. Infect. Control. 20, DOI: 10.1186/s13756-018-0438-6 (2018)
  36. Pestrak M.J., Chaney S.B., Eggleston H.C., Dellos-Nolan S., Dixit S., Mathew-Steiner S.S., Roy S., Parsek M.R., Sen Ch.K., Wozniak D.J.: Pseudomonas aeruginosa rugose small colony variants evade host clearance, are hyperinflammatory, and persist in multiple host environments. Plos Pathog. 14, e1006842 (2018)
  37. Podgórska B., Kędzia D.: From a commensal to a pathogen – two faces of Staphylococcus epidermidis. Post. Mikrobiol. 57, 338–348 (2018)
  38. Proctor R.A., van Langevelde P., Kristjansson, M., Maslow J.N., Arbeit R.D.: Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus. Clin Infect Dis. 20, 95–102 (1995)
  39. Proctor R.A., von Eiff C., Kahl B.C., Becker K., McNamara P., Herrmann M., Peters G.: Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections. Nat. Rev. Microbiol. 4, DOI: 10.1038/nrmicro1384 (2006)
  40. Riquelme S.A., Wong Fok Lung T., Prince A.: Pulmonary Pathogens Adapt to Immune Signaling Metabolites in the Airway. Front. Immunol. 11, DOI: 10.3389/fimmu.2020.00385 (2020)
  41. Rit K.: A case report of Small Colony variant of Staphylococcus aureus isolated from a patient with chronic oesteomyelitis in a tertiary care hospital of eastern India. Adv. Biomed. Res. 3, DOI: 10.4103/2277-9175.124683 (2014)
  42. Rudenko N., Golovchenko M., Kybicova K., Vancova M.: Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters. Parasites Vectors, 12, DOI: 10.1186/s13071-019-3495-7 (2019)
  43. Schneider M., Muhlemann K., Droz S., Couzinet S., Casaulta C., Zimmerli S.: Clinical characteristics associated with isolation of small-colony variants of Staphylococcus aureus and Pseudomonas aeruginosa from respiratory secretions of patients with cystic fibrosis. J. Clin. Microbiol. 46, 1832–1834 (2008)
  44. She P., Liu Y., Luo Z., Chen L., Zhou L., Hussain Z., Wu Y.: PA2146 Gene knockout is associated with Pseudomonas aeruginosa pathogenicity in macrophage and host immune response. Front. Cell. Infect. Microbiol. 10, DOI: 10.3389/fcimb.2020.559803 (2020)
  45. Stoneham S.M., Cantillon D.M., Waddell S.J., Llewelyn M.J.: Spontaneously occurring small-colony variants of Staphylococcus aureus show enhanced clearance by THP-1 macrophages. Front. Microbiol. 11, DOI: 10.3389/fmicb.2020.01300 (2020)
  46. Strzelec-Nowak D., Bogut A., Niedźwiadek J., Kozioł-Montewka M., Sikora A.: Mikrobiologiczna diagnostyka zakażeń implantów stawu biodrowego. Post. Mikrobiol. 51, 219–225 (2012)
  47. Szosland-Fałtyn A., Bartodziejska B.: Campylobacter jejuni Kameleon wśród bakterii – formy morfologiczne oraz ich patogenność. Kosmos Problemy Nauk Biologicznych, 67, 591–595 (2018)
  48. Tan N.C., Cooksley C.M., Roscioli E., Drilling A.J., Douglas R., Wormald P.J., Vreugde S.: Small-colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis. Allergy, 69, 1364–1371, DOI: 10.1111/all.12457 (2014)
  49. Tande A.J., Osmon D.R., Greenwood-Quaintance K.E., Mabry T.M., Hanssen A.D., Patel R.: Clinical characteristics and outcomes of prosthetic joint infection caused by small colony variant staphylococci. mBio, 30, e01910-14 (2014)
  50. Trafny E.A.: Wewnątrzkomórkowe bakterie względnie chorobotwórcze w zakażeniach górnych dróg oddechowych i ucha. Post. Mikrobiol. 51, 277–290 (2012)
  51. Tuchscherr L., Heitmann V., Hussain M., Viemann D., Roth J., von Eiff Ch., Peters G., Becker K., Lo¨ffler B.: Staphylococcus aureus Small-Colony Variants Are Adapted Phenotypes for Intracellular Persistence. J. Infect. Dis. 202, 1031–1040 (2010)
  52. Tuchscherr L., Lo¨ffler B.: i wsp. Staphylococcus aureus develops increased resistance to antibiotics by forming dynamic small colony variants during chronic osteomyelitis. J. Antimicrob. Chemother. 71, 438–448 (2016)
  53. Tuchscherr L., Löffler B., Proctor R.A.: Persistence of Staphylococcus aureus: multiple metabolic pathways impact the expression of virulence factors in small-colony variants (SCVs). Front. Microbiol. 11, DOI: 10.3389/fmicb.2020.01028 (2020)
  54. Urbanowicz P., Gniadkowski M.: CIĘŻKOZBROJNY” Pseudomonas aeruginosa: maecahnizmy lekooporności i ich tło genetyczne. Kosmos. Problemy Nauk Biologicznych, 66, 11–29 (2017)
  55. von Eiff Ch., Becker K., Metze D., Lubritz G., Hockmann J., Schwarz T., Peters G.: Intracellular Persistence of Staphylococcus aureus Small-Colony Variants within Keratinocytes: A Cause for Antibiotic Treatment Failure in a Patient with Darier’s Disease.Clin. Infect. Dis. 32, 1643–1647 (2001)
  56. von Eiff Ch., Vaudaux P., Kahl B.C., Lew D., Emler S., Schmidt A., Peters G., Proctor R.A.: Bloodstream infections caused by small-colony variants of coagulase-negative staphylococci following pacemaker implantation. Clin. Infect. Dis. 29, 932–934 (1999)
  57. Wang X., Zheng X., Huang M., Liu L.: A comparative genomic analysis of small-colony variant and wild-type Burkholderia pseudomallei in a patient with bacterial liver abscess. J. Glob. Antimicrob. Res. 21, 16–21 (2020)
  58. Yagci S., Hascelik G., Dogru D., Ozceli U., Senar B.: Prevalence and genetic diversity of Staphylococcus aureus small-colony variants in cystic fibrosis patients. Clin. Microbiol. Infect. 19, 77–84 (2013)
DOI: https://doi.org/10.21307/PM-2021.60.3.14 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
Language: English, Polish
Page range: 183 - 194
Submitted on: Jun 1, 2021
Accepted on: Aug 1, 2021
Published on: Sep 23, 2021
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Joanna Nowicka, Elżbieta Piątkowska, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.