Abstract
Introduction: Although there is no clear scientific evidence justifying antibiotic prophylaxis in operative treatment of hand and wrist bone fractures, it is commonly used, mostly due to the concern about possible medicolegal problems caused by bone infection after surgery.
The objective of this study was review of literature on the justification for the use of antibiotic prophylaxis in surgical treatment of hand and wrist fractures.
Results: For operative treatment of hand fractures 3 studies and 1 systematic review were found. All these articles indicate a lack of scientific evidence to justify the routine administration of antibiotics in these injuries. For operative treatment of distal radial fractures only 1 study was found suggesting that antibiotic prophylaxis does not affect risk of infection. Further literature review showed that redundant antibiotic use may be associated with harmful and adverse effects, as well as with substantial costs.
Conclusion: Current scientific evidence does not support routine use of antibiotic prophylaxis in operative treatment of hand and wrist bone fractures. Antibiotic administration in these operations has not effect for decreasing infection rate and therefore can be safely avoided.